Deformable Models And Their Application In Segmentation Of Imaged Pathology Specimens
Microsopic evaluation of peripheral blood smears and stained tissue analysis are performed routinely in pathology departments worldwide for cancer diagnosis and/or early detection. Recently, there has been an increase in the number of institutions using digital imaging and analysis to assist in assesment before a dignosis is rendered. Before the computer can be used to index, achive, analyze, or classify an imaged specimen, it must first be delineated into “homogeneous” regions based on the similarity of pixel attributes. Deformable models, or snakes, have gained significant attention and have become popular image segmentation methods since their first introduction by Kass, Witkin, and Terzopoulus in 1989. In this chapter, we will review recent advances and improvements on deformable models. We will focus primarily on the application and performance of different types of deformable models for analyzing microscopic pathology specimens.
KeywordsSegmentation Result Active Contour Finite Difference Method Color Version Deformable Model
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