QTL Mapping in Outbred Pedigrees
QTL mapping approaches were developed originally for experimental crosses, such as the backcross, double haploid, RILs, or F2, derived from inbred lines. Because of the homozygosity of inbred lines, the Mendelian (co)segregation of all markers with two alternative alleles in such crosses can be observed directly. In practice, there also is a group of species called outcrossing species, such as forest trees or large animals, in which it is difficult or impossible to generate inbred lines due to long generation intervals and high heterozygosity, although experimental hybrids can be commercially used for their genetic improvement.
KeywordsLinkage Group Wood Density Recombination Fraction Linkage Phase Epistatic QTLs
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