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Surgery pp 1827-1838 | Cite as

Transplantation of the Intestine

  • Fady M. Kaldas
  • Douglas G. Farmer

Abstract

The intestine was one of the last solid organs to be successfully transplanted. The reasons behind the barriers to successful intestinal transplantation (ITx) in humans are multifactorial. No doubt, the fact that the bowel is one of the largest and most active immune “organs” in the human body and the fact that bacteria and fungi reside in symbiosis within the lumen of the gut play a significant role. In fact, the immunogenicity of the intestine is so strong that successful transplantation was not possible without the advent of powerful immunosuppressive medications. This chapter outlines the development of this field, the surgical techniques used, the outcomes, as well as the major problems commonly seen after ITx.

Keywords

Transplant Proc Intestinal Transplantation Intestinal Failure Small Bowel Transplant Intestinal Graft 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Fady M. Kaldas
    • 1
  • Douglas G. Farmer
    • 2
    • 3
    • 4
    • 5
  1. 1.Department of SurgeryUniversity of CaliforniaLos AngelesUSA
  2. 2.Department of SurgeryDavid Geffen School of Medicine at UCLALos AngelesUSA
  3. 3.Intestinal Transplant ProgramDumont UCLA Transplant CenterLos AngelesUSA
  4. 4.Pediatric Liver Transplant ProgramDumont UCLA Transplant CenterLos AngelesUSA
  5. 5.Intestinal Failure Center, Division of Liver and Pancreas TransplantationDumont UCLA Transplant CenterLos AngelesUSA

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