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Venous Disease and Pulmonary Embolism

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Surgery

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Abstract

Venous thromboembolism (VTE) is an important cause of preventable morbidity and mortality in the United States. Although precise figures are difficult to obtain as a consequence of undiagnosed cases, the annual incidence of VTE has been estimated at 71 and 117 per 100,000 by two different recent retrospective population-based studies (Worcester and Olmstead Counties).1,2 Their reported annual incidences for deep venous thrombosis were nearly identical (48 per 100,000), but for pulmonary embolus (PE) there was great disparity (23 versus 69 per 100,000). This difference was believed to be secondary to the threefold higher rate of autopsy acquisition in Olmstead County as compared to the U.S. average.2 In-hospital case-fatality rates were also different, 12% versus 28%, respectively. Based on the Worcester data, Anderson and Wheeler have estimated the prevalence of clinically significant VTE at 600,000 cases per year, with as many as two-thirds of these being undiagnosed.3 Deep venous thrombosis (DVT) poses not only the immediate threat of pulmonary embolus (PE) but chronic disability secondary to venous insufficiency as well. PE is estimated to be responsible for the deaths of 50,000 to 100,000 persons per year in U.S. hospitals who would not otherwise be expected to die of their underlying disease process.4–6 Despite this awareness and evidence for the efficacy of various forms of prophylaxis, attention toward prevention remains inadequate.7

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Authors and Affiliations

  1. Department of Vascular Surgery, Oregon Health and Science University, Portland, OR, USA

    Gregory L. Moneta MD (Professor and Chief)

  2. Legacy Columbia Vascular and Endovascular Division, Legacy Emanuel Hospital and Health Center, Portland, OR, USA

    Mathew I. Foley MD (Vascular Surgeon)

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Editors and Affiliations

  1. Department of Surgery, Stanford University Medical Center, Stanford, CA, USA

    Jeffrey A. Norton MD, FACS (Robert L. and Mary Ellenburg Professor, Chief) (Robert L. and Mary Ellenburg Professor, Chief)

  2. Divisions of Surgical Oncology and General Surgery, Department of Surgery, Stanford University Medical Center, Stanford, CA, USA

    Jeffrey A. Norton MD, FACS (Robert L. and Mary Ellenburg Professor, Chief) (Robert L. and Mary Ellenburg Professor, Chief)

  3. Departments of Surgery and Public Health, New York-Presbyterian Hospital/Weill Cornell Medical College, New York, NY, USA

    Philip S. Barie MD, MBA, FCCM, FACS (Professor, Chief) (Professor, Chief)

  4. Division of Critical Care and Trauma, NewYork-Presbyterian Hospital/Weill Cornell Medical College, New York, NY, USA

    Philip S. Barie MD, MBA, FCCM, FACS (Professor, Chief) (Professor, Chief)

  5. Departments of Surgery and Immunology, Duke University Medical Center, Durham, NC, USA

    R. Randal Bollinger MD, PhD, FACS (Professor) (Professor)

  6. Division of Surgical Oncology, Department of Surgery, University of Michigan, Comprehensive Cancer Center, Ann Arbor, MI, USA

    Alfred E. Chang MD, FACS (Chief, Hugh Cabot Professor of Surgery) (Chief, Hugh Cabot Professor of Surgery)

  7. Department of Surgery, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ, USA

    Stephen F. Lowry MD, MBA, FACS (Professor and Chairman) (Professor and Chairman)

  8. Robert Wood Johnson Medical School, New Brunswick, NJ, USA

    Stephen F. Lowry MD, MBA, FACS (Professor and Chairman) (Professor and Chairman)

  9. Department of Surgery, The University of Utah, Salt Lake City, UT, USA

    Sean J. Mulvihill MD, FACS (Professor and Chair, Senior Director of Clinical Affairs) (Professor and Chair, Senior Director of Clinical Affairs)

  10. Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT, USA

    Sean J. Mulvihill MD, FACS (Professor and Chair, Senior Director of Clinical Affairs) (Professor and Chair, Senior Director of Clinical Affairs)

  11. Departments of Cardiothoracic Surgery and Surgery, New York University Medical Center, New York, NY, USA

    Harvey I. Pass MD, FACS (Professor) (Professor)

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    Robert W. Thompson MD, FACS (Professor of Surgery (Section of Vascular Surgery), Vice-Chairman for Research) (Professor of Surgery (Section of Vascular Surgery), Vice-Chairman for Research)

  13. Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA

    Robert W. Thompson MD, FACS (Professor of Surgery (Section of Vascular Surgery), Vice-Chairman for Research) (Professor of Surgery (Section of Vascular Surgery), Vice-Chairman for Research)

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Moneta, G.L., Foley, M.I. (2008). Venous Disease and Pulmonary Embolism. In: Norton, J.A., et al. Surgery. Springer, New York, NY. https://doi.org/10.1007/978-0-387-68113-9_68

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