Surgery pp 827-839 | Cite as

Malignant Tumors of the Esophagus

  • Gail Darling


Carcinoma of the esophagus is the 10th leading cause of cancer deaths in North America. The incidence varies considerably from 5 per 100,000 in most Western countries to as high as 100 per 100,000 in some countries such as Iran, Japan, China, and other countries in the “esophageal cancer belt.” The estimated 5-year survival for cancer of the esophagus is 10%. Adenocarcinoma, previously rare, is increasing in incidence in Western countries by approximately 5%–10% per year1,2 and is now the dominant cell type in patients in North America and Europe, although squamous cell carcinoma still dominates globally. In a recent series of patients with esophageal cancer from the Mayo Clinic,3 adenocarcinoma was present in 85.5%. Adenocarcinoma and squamous cell cancer account for almost all cases. Leiomyosarcoma, lymphoma, small-cell carcinoma, and melanoma occur rarely.


Esophageal Cancer Esophageal Carcinoma Preoperative Chemotherapy Radiation Therapy Oncology Group Thoracic Esophagus 
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© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Gail Darling
    • 1
  1. 1.Department of Thoracic SurgeryUniversity Health NetworkTorontoCanada

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