Surgery pp 2291-2304 | Cite as

Biomaterials and the Evolution of Hernia Repair I: The History of Biomaterials and the Permanent Meshes

  • Raul A. Cortes
  • Edward Miranda
  • Hanmin Lee
  • Michael E. Gertner


Increasingly, bioprosthetic materials are being used for a variety of surgical applications. In general surgery, for example, surgical techniques for hernia repair have been influenced directly by the development of different prosthetic meshes. As the field of biomaterial science advances, new insight into the physiological response to materials guides the development of newer classes of biomaterials including synthetic, partially synthetic, and natural tissue derivatives. This chapter, the first of three parts on materials for hernia repair, outlines historical aspects of bioprosthetic materials, details experimental (often animal) and clinical evidence for use of current materials, and establishes a framework for understanding the principles used for development of new prostheses. Although hernias serve as the model disease, the fundamentals of bio-prostheses interactions are applicable to many different genres in medicine.


Hernia Repair Incisional Hernia Inguinal Hernia Repair Ventral Hernia Polypropylene Mesh 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Raul A. Cortes
    • 1
  • Edward Miranda
    • 2
  • Hanmin Lee
    • 3
  • Michael E. Gertner
    • 4
  1. 1.Department of SurgeryUniversity of California, San FranciscoSan FranciscoUSA
  2. 2.Department of Plastic and Reconstructive SurgeryCalifornia-Pacific Medical CenterSan FranciscoUSA
  3. 3.Department of Surgery, Pediatrics, and OB-Gyn and Reproductive ServicesUniversity of California, San FranciscoSan FranciscoUSA
  4. 4.Department of SurgeryStanford UniversityStanfordUSA

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