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Papillary Thyroid Carcinoma

  • Cristian Slough
  • Gregory W. Randolph

Abstract

A computerized PubMed search of MEDLINE 1966–May 2006 was performed. The terms “thyroid,” “papillary,” and “thyroidectomy” were exploded and the resulting articles were cross-referenced, yielding 2203 trials. An additional search was performed to identify those that mapped to the medical subject headings “thyroid neoplasms” and “thyroidectomy,” as well as the text word “papillary,” which yielded 1139 studies. These articles were then reviewed to identify those that met the following inclusion criteria: 1) patient population with “low risk papillary thyroid carcinoma,” 2) intervention with total thyroidectomy versus unilateral lobectomy, 3) outcome measured in terms of survival (cause specific, overall, or otherwise) and disease recurrence. Articles were excluded if they included mixed follicular and papillary groups or did not specifically analyze low-risk groups. Many related papers pooled papillary and follicular cancers together. Although these two cancers are similar, they are also separate entities with clearly different natural histories and patterns of spread.

Keywords

Thyroid Cancer Thyroid Carcinoma Papillary Thyroid Carcinoma Total Thyroidectomy Differentiate Thyroid Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Haigh PI, Urbach DR, Rotstein LE. Extent of thyroidectomy is not a major determinant of survival in low-or high-risk papillary thyroid cancer. Ann Surg Oncol 2005;12(1):81–89.CrossRefPubMedGoogle Scholar
  2. 2.
    Hay ID, Grant CS, Bergstralh EJ, Thompson GB, van Heerden JA, Goellner JR. Unilateral total lobectomy: is it sufficient surgical treatment for patients with AMES low-risk papillary thyroid carcinoma? Surgery 1998;124(6):958–964.PubMedGoogle Scholar
  3. 3.
    Hay ID, Thompson GB, Grant CS, et al. Papillary thyroid carcinoma managed at the Mayo Clinic during six decades (1940–1999): temporal trends in initial therapy and long-term outcome in 2444 consecutively treated patients. World J Surg 2002;26(8):879–885.CrossRefPubMedGoogle Scholar

References

  1. 1.
    Brierley J, Tsang R, Panzarella T, Bana N. Prognostic factor and the effect of treatment with radioactive iodine and external beam radiation on patients with differentiated thyroid cancer seen at a single institution over the 40 years. Clin Endocrinol 2005;63:418–427.CrossRefGoogle Scholar
  2. 2.
    Chow SM, Law SCK, Mendenhall WM, et al. Papillary thyroid carcinoma: prognostic factors and the role of radio-iodine and external radiotherapy. Int J Radiat Oncol Biol Phys 2002;52:784–795.CrossRefPubMedGoogle Scholar
  3. 3.
    Sanders LE, Cady B. Differentiated thyroid cancer: re-examination of risk groups and outcome of treatment. Arch Surg 1998;133:419–425.CrossRefPubMedGoogle Scholar
  4. 4.
    Greene FL, Page DL, Fleming ID, et al. AJCC Cancer Staging Manual. 6th ed. New York: Springer; 2002.Google Scholar
  5. 5.
    Cady B, Rossi R. An expanded view of risk-group definition in differentiated thyroid carcinoma. Surgery 1988;104:947–953.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Cristian Slough
    • 1
  • Gregory W. Randolph
    • 2
  1. 1.Department of OtolaryngologyOregon Health and Science UniversityPortlandUSA
  2. 2.Department of Otolaryngology-Head and Neck SurgeryMassachusetts Eye and Ear InfirmaryBostonUSA

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