Papillary Thyroid Carcinoma
A computerized PubMed search of MEDLINE 1966–May 2006 was performed. The terms “thyroid,” “papillary,” and “thyroidectomy” were exploded and the resulting articles were cross-referenced, yielding 2203 trials. An additional search was performed to identify those that mapped to the medical subject headings “thyroid neoplasms” and “thyroidectomy,” as well as the text word “papillary,” which yielded 1139 studies. These articles were then reviewed to identify those that met the following inclusion criteria: 1) patient population with “low risk papillary thyroid carcinoma,” 2) intervention with total thyroidectomy versus unilateral lobectomy, 3) outcome measured in terms of survival (cause specific, overall, or otherwise) and disease recurrence. Articles were excluded if they included mixed follicular and papillary groups or did not specifically analyze low-risk groups. Many related papers pooled papillary and follicular cancers together. Although these two cancers are similar, they are also separate entities with clearly different natural histories and patterns of spread.
KeywordsThyroid Cancer Thyroid Carcinoma Papillary Thyroid Carcinoma Total Thyroidectomy Differentiate Thyroid Cancer
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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