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Prophylaxis in Head and Neck Surgery

  • Jennifer J. Shin
  • Jonas T. Johnson

Abstract

A computerized PubMed search of MEDLINE 1966-December 2005 was performed. Articles that mapped to the medical subject headings “antibiotic prophylaxis,” “anti-bacterial agents,” “lactams,” “fluoroquinolones,” “macrolides,” or “clindamycin” were collected into one group. A second group was created by identifying articles that mapped to the medical subject heading “head and neck neoplasms,” cross-referenced with those mapping to the medical subject heading “perioperative care” or the subheading “surgery.” These articles were then reviewed to identify those that met the following inclusion criteria: 1) patient population undergoing clean-contaminated surgery for head and neoplasm, 2) intervention with 1-day versus longer-course systemic antibiotic therapy, 3) outcome measured in terms of surgical-site wound infections, 4) randomized controlled trials (RCTs). Excluded were data from articles in which only clean, noncontaminated wounds, distant infections, and non-head and neck surgery were evaluated.

Keywords

Pulmonary Embolism Deep Vein Thrombosis Medical Subject Heading Subcutaneous Heparin Heparin Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Jennifer J. Shin
    • 1
  • Jonas T. Johnson
    • 2
  1. 1.Harvard Program in Otolaryngology-Head and Neck SurgeryMassachusetts Eye and Ear InfirmaryBostonUSA
  2. 2.Department of OtolaryngologyPittsburgh School of Medicine, Eye and Ear InstitutePittsburghUSA

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