Abstract
A computerized PubMed search of MEDLINE 1966-December 2005 was performed. Articles that mapped to the medical subject headings “antibiotic prophylaxis,” “anti-bacterial agents,” “lactams,” “fluoroquinolones,” “macrolides,” or “clindamycin” were collected into one group. A second group was created by identifying articles that mapped to the medical subject heading “head and neck neoplasms,” cross-referenced with those mapping to the medical subject heading “perioperative care” or the subheading “surgery.” These articles were then reviewed to identify those that met the following inclusion criteria: 1) patient population undergoing clean-contaminated surgery for head and neoplasm, 2) intervention with 1-day versus longer-course systemic antibiotic therapy, 3) outcome measured in terms of surgical-site wound infections, 4) randomized controlled trials (RCTs). Excluded were data from articles in which only clean, noncontaminated wounds, distant infections, and non-head and neck surgery were evaluated.
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References
Righi M, Manfredi R, Farneti G, Pasquini E, Romei Bugliari D, Cenacchi V. Clindamycin/cefonicid in head and neck oncoiogic surgery: one-day prophylaxis is as effective as a three-day schedules. J Chemother 1995;7(3):216–220.
Righi M, Manfredi R, Farneti G, Pasquini E, Cenacchi V. Short-term versus long-term antimicrobial prophylaxis in oncologic head and neck surgery. Head Neck. 1996 Sep–Oct; 18(5):399–404. In head and neck oncologic surgery: one-day prophylaxis is as effective as a three-day schedule. J Chemother. 1995 Jun; 7(3):216–220.
Johnson JT, Schuller DE, Silver F, et al. Antibiotic prophylaxis in high-risk head and neck surgery: one-day versus five-day therapy. Otolaryngol Head Neck Surg 1986;95: 554.
Carroll WR, Rosenstiel D, Fix JR, et al. Three-dose vs extended-course clindamycin prophylaxis for free-flap reconstruction of the head and neck. Arch Otolaryngol Head Neck Surg 2003;129(7):771–774.
Brand B, Johnson JT, Myers EN, Thearle PB, Sigler BA. Prophylactic perioperative antibiotics in contaminated head and neck surgery. Otolaryngol Head Neck Surg 1982;90(3 Pt 1): 315–318.
Bhathena HM, Kavarana NM. Prophylactic antibiotics administration head and neck cancer surgery with major flap reconstruction: 1-day cefoperzone versus 5-day cefotaxime. Acta Chir Plast 1998;40(2):36–40.
Piccart M, Dor P, Klastersky J. Antimicrobial prophylaxis of infections in head and neck cancer surgery. Scand J Infect Dis Suppl 1983;39:92–96.
Mombelli G, Coppens L, Dor P, Klastersky J. Antibiotic prophylaxis in surgery for head and neck cancer. Comparative study of short and prolonged administration of carbenicillin. J Antimicrob Chemother 1981;7(6):665–671.
References
Abraham-Inpijn L. Critical evaluation of low-dose heparin in laryngectomy. Arch Chir Neerl 1979;31(1):9–15.
Moreano EH, Hutchison JL, McCulloch TM, Graham SM, Funk GF, Hoffman HT. Incidence of deep venous thrombosis and pulmonary embolism in otolaryngology-head and neck surgery. Otolaryngol Head Neck Surg 1998;118(6):777–784.
Graham JM, Robinson JM, Ashcroft PB, Glennie R. Deep vein thrombosis in ear, nose and throat surgery. J Laryngol Otol 1976;90(5):427–432.
References
Ginzburg E, Cohn SM, Lopez J, Jackowski J, Brown M, Hameed SM. Deep Vein Thrombosis Study Group. “Randomized clinical trial of intermittent pneumatic compression and low molecular weight heparin in trama”. Br J Surg. 2003 Nov; 90(11):1338–44.
Warwick D, Harrison J, Glew D, Mitchelmore A, Peters TJ, Donovan J. Comparison of the use of a foot pump with the use of low-molecular-weight heparin for the prevention of deep-vein thrombosis after total hip replacement. A prospective, randomized trial. J Bone Joint Surg Am. 1998 Aug; 80(8):1158–66.
Nicolaides AN, Fernandes e Fernandes J, Pollock AV. “Intermittent sequential pneumatic compression of the legs in the prevention of venous stasis and postoperative deep venous thrombosis.” Surgery. 1980 Jan; 87(1): 69–76.
Rasmussen A, Hansen PT, Lindholt J, Poulsen TD, Toftdahl DB, Gram J, Toftgaard C, Jespersen J. “Venous thrombosis after abdominal surgery. A comparison between subcutaneous heparin and antithrombotic stockings, or both.” J Med. 1988;19(3–4):193–201.
Maxwell GL, Synan I, Dodge R, Carroll B, Clarke-Pearson DL. “Pneumatic compression versus low molecular weight heparin in gynecologic oncology surgery: a randomized trial.” Obstet Gynecol. 2001 Dec;98(6):989–95.
Clarke-Pearson DL, Synan IS, Dodge R, Soper JT, Berchuk A, Coleman RE. “A Randomized Trial of Low-Dose Heparin and Intermittent Pneumatic Calf Compression for the prevention of deep venous thrombosis after gynecologic oncology surgery. Am J Obstet Gynec. 1993; 168(4):1146–1154.
Pitto RP, Hamer H, Heiss-Dunlop W, Kuehle J. Mechanical prophylaxis of deep-vein thrombosis after total hip replacement a randomised clinical trial. J Bone Joint Surg Br. 2004 Jul;86(5):639–42.
Kosir MA, Schmittinger L, Barno-Winarski L, Duddella P, Pone M, Perales A, Lange P, Brish LK, McGee K, Beleski K, Pawlak J, Mammen E, Sajahan NP, Kozol RA. “Prospective double-arm study of fibrinolysis in surgical patients.” J Surg Res. 1998 Jan;74(1):96–101.
Kurtoglu M, Yanar H, Bilsel Y, Guloglu R, Kizilirmak S, Buyukkurt D, Granit V. “Venous thromboembolism prophylaxis after head and spinal trauma: intermittent pneumatic compression devices versus low molecular weight heparin” World J Surg. 2004 Aug;28(8):807–11. Epub 2004 Aug 3.
Blanchard J, Meuwly JY, Leyvraz PF, Miron MJ, Bounameaux H, Hoffmeyer P, Didier D, Schneider PA. “Prevention of deep-vein thrombosis after total knee replacement. Randomised comparison between a low-molecular-weight heparin (nadroparin) and mechanical prophylaxis with a foot-pump system.“ J Bone Joint Surg Br. 1990 Jul;81(4): 654–9.
Nicolaides AN, Miles C, Hoare M, Jury P, Helmis E, Venniker R. “Intermittent sequential pneumatic compression of the legs and thromboembolism-deterrent stockings in the prevention of postoperative deep venous thrombosis.” Surgery. 1983 Jul;94(1):21–5.
Coe NP, Collins RE, Klein LA, Bettmann MA, Skillman JJ, Shapiro RM, Salzman EW. “Prevention of deep vein thrombosis in urological patients: a controlled, randomized trial of low-dose heparin and external pneumatic compression boots.” Surgery. 1978 Feb;83(2): 230–4.
Santori FS, Vitullo A, Stopponi M, Santori N, Ghera S. “Prophylaxis against deep-vein in total hip replacement. Comparison of heparin and foot impulse pump.” J Bone Joint Surg Br. 1994 Jul;76(4):579–583.
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Shin, J.J., Johnson, J.T. (2008). Prophylaxis in Head and Neck Surgery. In: Shin, J.J., et al. Evidence-Based Otolaryngology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-49979-6_27
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DOI: https://doi.org/10.1007/978-0-387-49979-6_27
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