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Survival Analysis

  • Sandra S. Stinnett

Abstract

Survival analysis is concerned with time to the occurrence of an event, such as death, recurrence or disease, or failure of an implanted medical device. Computing only the overall proportion surviving the event neglects the important aspect of time. We need a measure that accounts not only for whether patients die, but also for when they die. In other words, we want to look at the pattern of dying over time.

Keywords

Thyroid Carcinoma Survival Function Laryngeal Cancer Adenoid Cystic Carcinoma Oral Squamous Cell Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    SAS/STAT® User’s Guide. Version 8. Cary, NC: SAS Institute; 1999 (Procedures LIFETEST and PHREG).Google Scholar
  2. 2.
    Norman GR, Streiner DL. Biostatistics. The Bare Essentials. Hamilton, Ontario: BC Decker; 2000: Chapter 24.Google Scholar
  3. 3.
    Dawson B, Trapp RG. Basic and Clinical Biostatistics. 4th ed. New York: McGraw-Hill; 2004: Chapters 9 and 10.Google Scholar
  4. 4.
    Bhattacharyya N. Contemporary staging and prognosis for primary tracheal malignancies: a population-based analysis. Otolaryngol Head Neck Surg 2004;131(5):639–642.CrossRefPubMedGoogle Scholar
  5. 5.
    Bhattacharyya N, Nayak VK. Survival outcomes for second primary head and neck cancer: a matched analysis. Otolaryngol Head Neck Surg 2004;131(2):P62–P63.CrossRefGoogle Scholar
  6. 6.
    Gallo O, Sarno A, Baroncelli R, Bruschini L, Boddi V. Multivariate analysis of prognostic factors in T3 N0 laryngeal carcinoma treated with total laryngectomy. Otolaryngol Head Neck Surg 2003;128(5):654–662.CrossRefPubMedGoogle Scholar
  7. 7.
    Bhattacharyya N. A population-based analysis of survival factors in differentiated and medullary thyroid carcinoma. Otolaryngol Head Neck Surg 2003;128(1):115–123.CrossRefPubMedGoogle Scholar
  8. 8.
    Carinci F, Farina A, Pulicchi S, et al. Stage grouping reliability: TNM’ 97 versus TANIS in laryngeal cancer. Otolaryngol Head Neck Surg 1999;120(4):499–501.CrossRefPubMedGoogle Scholar
  9. 9.
    Marshak G, Rakowsky E, Schachter J, et al. Is the delay in starting postoperative radiotherapy a key factor in the outcome of advanced (T3 and T4) laryngeal cancer? Otolaryngol Head Neck Surg 2004;131(4):489–493.CrossRefPubMedGoogle Scholar
  10. 10.
    Bernaldez R, García-Pallarés M, Morera E, Lassaletta L, del Palacio A, Gavilán J. Oncologic and functional results of near-total laryngectomy. Otolaryngol Head Neck Surg 2003;128(5):700–705.CrossRefPubMedGoogle Scholar
  11. 11.
    Lassaletta L, García-Pallarés M, Morera E, Bernáldez R, Gavilan J. T3 glottic cancer: oncologic results and prognostic factors. Otolaryngol Head Neck Surg 2001;124(5):556–560.CrossRefPubMedGoogle Scholar
  12. 12.
    Bockmühl U, Ishwad CS, Ferrell RE, Gollin SM. Association of 8p23 deletions with poor survival in head and neck cancer. Otolaryngol Head Neck Surg 2001;124(4):451–455.CrossRefPubMedGoogle Scholar
  13. 13.
    Lima RA, Freitas EQ, Kligerman J, et al. Supracricoid laryngectomy with CHEP: functional results and outcome. Otolaryngol Head Neck Surg 2001;124(3):258–260.CrossRefPubMedGoogle Scholar
  14. 14.
    Ortiz S, Rodríguez JM, Soria T, et al. Extrathyroid spread in papillary carcinoma of the thyroid: clinicopathological and prognostic study. Otolaryngol Head Neck Surg 2001; 124(3):261–265.CrossRefPubMedGoogle Scholar
  15. 15.
    De Stefani A, Magnano M, Cavalot A, et al. Adjuvant radiotherapy influences the survival of patients with squamous carcinoma of the head and neck who have poor prognoses. Otolaryngol Head Neck Surg 2000;123(5):630–636.CrossRefPubMedGoogle Scholar
  16. 16.
    Peretti G, Nicolai P, de Zinis LOR, et al. Endoscopic CO laser excision for Tis, T1, and T2 glottic carcinomas: cure rate and prognostic factors. Otolaryngol Head Neck Surg 2000;123(1):124–131.CrossRefPubMedGoogle Scholar
  17. 17.
    Schwartz SR, Yueh B, McDougall JK, Daling JR, Schwartz SM. Human papillomavirus infection and survival in oral squamous cell cancer: a population-based study. Otolaryngol Head Neck Surg 2001;125(1):1–9.CrossRefPubMedGoogle Scholar

For Further Study

  1. 1.
    Kirkwood BR, Sterne AC. Essential Medical Statistics. 2nd ed. Oxford UK: Blackwell Science; 2003: Chapter 26.Google Scholar
  2. 2.
    Banerjee A. Medical Statistics Made Clear: An Introduction to Basic Concepts. London: Royal Society of Medicine Press; 2003: Chapter 10.Google Scholar
  3. 3.
    Rosner B. Fundamentals of Biostatistics. 5th ed. Pacific Grove, CA: Duxbury; 2000: Chapter 14.Google Scholar
  4. 4.
    Aviva P, Sabin C. Medical Statistics at a Glance. Oxford, UK: Blackwell Science; 2000: Chapter 41.Google Scholar
  5. 5.
    Chang KP, Hao SP, Tsang NM. The 30-bp deletion from LMP-1 gene in the clinicopathological manifestation of NPC tumors. Otolaryngol Head Neck Surg 2004;131(2):P113–P114.CrossRefGoogle Scholar
  6. 6.
    Ow TJ, Lin SJ, Mittal B, et al. Adenoid cystic carcinoma in the head and neck: an updated survival analysis. Otolaryngol Head Neck Surg 2004;131(2):P242–P243.Google Scholar
  7. 7.
    Ozdek A, Sarac S, Akyol MU, Sungur A, Yilmaz T. c-myc and bcl-2 expression in supraglottic squamous cell carcinoma of the larynx. Otolaryngol Head Neck Surg 2004; 131(1):77–83.CrossRefPubMedGoogle Scholar
  8. 8.
    Nathan CAO, Amirghahari N, Rong X, Zhou H, Harrison L. EIF4E overexpression may confer radioresistance in a head and neck cancer cell line. Otolaryngol Head Neck Surg 2004;131(2):P178–P179.CrossRefGoogle Scholar
  9. 9.
    Arora A, Mutairy AA, Harmer C, Rhys-Evans P. Comparison of surgery versus combined modality treatment in pt4 thyroid cancer. Otolaryngol Head Neck Surg 2004;131(2):P182.CrossRefGoogle Scholar
  10. 10.
    Arora A, Powles J, Vini L, et al. The long-term outcome of patients with locally advanced thyroid carcinoma. Otolaryngol Head Neck Surg 2004;131(2):P183.CrossRefGoogle Scholar
  11. 11.
    Kazi RA, Rhys Evans PH. A retrospective analysis of surgery for the oral cavity and oropharyngeal squamous cell carcinoma. Otolaryngol Head Neck Surg 2004;131(2):P234.CrossRefGoogle Scholar
  12. 12.
    Ozdek A, Sarac S, Akyol MU, Sungur A, Yilmaz T. c-myc and bcl-2 expression in supraglottic squamous cell carcinoma of the larynx. Otolaryngol Head Neck Surg 2004; 131(1):77–83.CrossRefPubMedGoogle Scholar
  13. 13.
    Paleri V, Pearson JP, Bulmer D, Jeannon JP, Wight RG, Wilson JA. Expression of mucin gene products in laryngeal squamous cancer. Otolaryngol Head Neck Surg 2004; 131(1):84–88.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Sandra S. Stinnett
    • 1
  1. 1.Department of OtolaryngologyDuke University Medical CenterDurhamUSA

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