Adult Laryngopharyngeal Reflux
A computerized PubMed search of MEDLINE 1966-January 2006 was performed using the terms “laryngopharyngeal reflux” (LPR) and “supraesophageal reflux disease.” The resulting articles were combined into a first group and cross-referenced with a second group of articles using the keywords “treatment of reflux.” This process yielded 91 articles which were reviewed. Their references were manually cross-checked for any further relevant articles which yielded three additional pertinent studes. This search was reverified by cross-referencing studies that mapped to both the medical subject heading “gastroesophageal reflux” and “laryngeal disease.” All of these articles were reviewed to determine which met the following inclusion criteria: 1) distinct patient population of adults (>-18 years old) with symptoms and signs suggesting LPR, 2) intervention with a proton pump inhibitor (PPI) versus placebo, 3) outcome measured by patient questionnaire and video laryngoscopy.
KeywordsReflux Symptom Proton Pump Inhibitor Therapy Video Laryngoscopy Laryngopharyngeal Reflux Chronic Laryngitis
Unable to display preview. Download preview PDF.
- 5.Havas T, Huang S, Levy M, et al. Posterior pharyngolaryngitis double-blind randomised placebo-controlled trial of proton pump inhibitor therapy. Aust J Otolaryngol 1999; 3(3):243–246.Google Scholar