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Chronic Rhinosinusitis in Adults

  • Stacey Gray
  • Jennifer J. Shin
  • Ralph Metson
  • Gregory W. Randolph

Abstract

A computerized PubMed search of MEDLINE 1966-April 2006 was performed. Articles mapping to the medical subject heading “sinusitis” and textwords “chronic” or “recurrent” were obtained, yielding 2503 studies. These articles were then cross-referenced with those publications mapping to the medical subject headings “anti-bacterial agents” or “quinolones” or “penicillins” or “macrolides” or “cephalosporins” or “clindamycin” or the textwords “antibiotics” or “antimicrobials.” This search strategy yielded 447 articles. These publications were then reviewed to identify those that met the following inclusion criteria: 1) adult patient population (>15 years old) with chronic or recurrent rhinosinusitis, 2) intervention with comparative oral antibiotic regimens, 3) outcome measured in terms of clinical improvement, 4) randomized controlled trials (RCTs). Articles focusing only on patients with acute rhinosinusitis were excluded.

Keywords

Chronic Rhinosinusitis Endoscopic Sinus Surgery Chronic Sinusitis Primary Ciliary Dyskinesia Compute Tomography Score 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Stacey Gray
    • 1
  • Jennifer J. Shin
    • 2
  • Ralph Metson
    • 1
  • Gregory W. Randolph
    • 1
  1. 1.Department of Otolaryngology-Head and Neck SurgeryMassachusetts Eye and Ear InfirmaryBostonUSA
  2. 2.Harvard Program in Otolaryngology-Head and Neck SurgeryMassachusetts Eye and Ear InfirmaryBostonUSA

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