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Obstructive Sleep Apnea in Adults

  • David P. White
  • Roger S. Smith
  • Mary Beauchamp
  • Regina P. Walker
  • Kenny Pang
  • Kenny Pang

Abstract

A computerized PubMed search of MEDLINE 1966–February 2006 was performed. The terms “CPAP” (continuous positive airway pressure) and “randomized clinical trial” were exploded and the resulting articles were cross-referenced, yielding 322 trials. These articles were then reviewed to identify those that met the following inclusion criteria: 1) patient population with obstructive sleep apnea of all severity levels, 2) intervention with CPAP for at least 1 month, and 3) used a realistic placebo methodology (subtherapeutic or sham CPAP [1, 2, 3]). All outcomes were examined. Articles in which a pill was used as the placebo were excluded [4, 5, 6, 7, 8]. The bibliographies of the articles that met these inclusion criteria were manually checked to ensure no further relevant articles could be identified. This process yielded three articles.

Keywords

Obstructive Sleep Apnea Sleep Apnea Continuous Positive Airway Pressure Obstructive Sleep Apnea Syndrome Epworth Sleepiness Scale 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • David P. White
    • 1
  • Roger S. Smith
    • 2
  • Mary Beauchamp
    • 3
  • Regina P. Walker
    • 4
  • Kenny Pang
    • 5
  • Kenny Pang
    • 5
  1. 1.Sleep Medicine DivisionBrigham and Women’s HospitalBostonUSA
  2. 2.Clinical Instructor in MedicineHarvard Medical SchoolBostonUSA
  3. 3.OtolaryngologyLoyola University Medical CenterMaywoodUSA
  4. 4.Department of Otolaryngology-Head and Neck Surgery, LoyolaUniversity Medical CenterMaywoodUSA
  5. 5.Department of OtolaryngologyTan Tock Seng HospitalSingapore

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