Advertisement

Sudden Sensorineural Hearing Loss

  • Jennifer J. Shin
  • Steven D. Rauch

Abstract

A computerized Ovid search of MEDLINE 1970-March 2004 was performed. The terms “hearing loss,” “deafness,” “hearing loss, sensorineural,” and “hearing loss, sudden” were exploded and the resulting articles were combined. These articles were then cross-referenced with articles obtained by exploding the term “steroids.” This process yielded 320 publications. These studies were then reviewed to identify those that met the following inclusion criteria: 1) a discrete set of patients with idiopathic sensorineural hearing loss (SNHL) of “acute” or “sudden” onset or occurring over ≤3 days, 2) intervention with systemic steroids versus placebo or systemic steroids versus no intervention, 3) outcome measured with standard audiometry (i.e., pure tone and speech reception thresholds, speech discrimination scores). Studies with the following characteristics were excluded: a) patients with a known cause of SNHL, nonacute or repetitive SHNL, b) intervention with intratympanic steroids (see Section 13.D), c) comparison of steroids with another therapy, d) amalgamation of patients receiving other treatments with either the steroid or nonsteroid treatment groups.

Keywords

Hearing Loss Sensorineural Hearing Loss Systemic Steroid Pure Tone Average Sudden Sensorineural Hearing Loss 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Wilson WR, Byl FM, Laird N. The efficacy of steroids in the treatment of idiopathic sudden hearing loss. Arch Otolaryngol Head Neck Surg 1980;106:772–776.Google Scholar
  2. 2.
    Cinamon U, Bendet E, Kronenberg J. Steroids, carbogen, or placebo for sudden hearing loss: a prospective double-blind study. Eur Arch Otorhinolaryngol 2001;258:477–480.CrossRefPubMedGoogle Scholar
  3. 3.
    Chen CY, Halpin C, Rauch SD. Oral steroid treatment of sudden sensorineural hearing loss: a ten year retrospective analysis. Otol Neurotol 2003;24:728–733.CrossRefPubMedGoogle Scholar
  4. 4.
    Moskowitz D, Lee KJ, Smith HW. Steroid use in idiopathic sudden sensorineural hearing loss. Laryngoscope 1984;94: 664–666.CrossRefPubMedGoogle Scholar
  5. 5.
    Byl FM. Seventy-six cases of presumed hearing loss occurring in 1973: prognosis and incidence. Laryngoscope 1977; 87(5):817–825.CrossRefPubMedGoogle Scholar
  6. 6.
    Simmons FB. Sudden idiopathic sensorineural hearing loss: some observations. Laryngoscope 1973;83(8):1221–1227.CrossRefPubMedGoogle Scholar

References

  1. 1.
    Westerlaken BO, Stokroos RJ, Dhooge IJ, Wit HP, Albers FW. Treatment of idiopathic sudden sensorineural hearing loss with antiviral therapy: a prospective, randomized, double-blind clinical trial. Ann Otol Rhinol Laryngol 2003;112(11):993–1000.PubMedGoogle Scholar
  2. 2.
    Uri N, Doweck I, Cohen-Kerem R, Greenberg E. Acyclovir in the treatment of idiopathic sudden sensorineural hearing loss. Otolaryngol Head Neck Surg 2003;128(4):544–549.CrossRefPubMedGoogle Scholar
  3. 3.
    Stokroos RJ, Albers FW, Tenvergert EM. Antiviral treatment of idiopathic sudden sensorineural hearing loss: a prospective, randomized, double-blind clinical trial. Acta Otolaryngol 1998;118(4):488–495.CrossRefPubMedGoogle Scholar

References

  1. 1.
    Tucci DL, Farmer JC Jr, Kitch RD, Witsell DL. Treatment of sudden sensorineural hearing loss with systemic steroids and valcyclovir. Otol Neurotol 2002;23(3):301–308.CrossRefPubMedGoogle Scholar
  2. 2.
    Zadeh MH, Storper IS, Spitzer JB. Diagnosis and treatment of sudden-onset sensorineural hearing loss: a study of 51 patients. Otolaryngol Head Neck Surg 2003;128(1):92–98.CrossRefPubMedGoogle Scholar
  3. 3.
    Campbell DT, Fiske DW. Convergent and discriminant validation by the multitrait-multimethod matrix. Psychol Bull 1959;56:81–105.CrossRefPubMedGoogle Scholar
  4. 4.
    Trochim WM. Research Methods Knowledge Base. New York: Cornell University; 2000.Google Scholar

References

  1. 1.
    Lefebvre PP, Staecker H. Steroid perfusion of the inner ear for sudden sensorineural hearing loss after failure of conventional therapy: a pilot study. Acta Otolaryngol 2002; 122:698–702.CrossRefPubMedGoogle Scholar
  2. 2.
    Parnes LS, Sun AH, Freeman DJ. Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application. Laryngoscope 1999;109(Suppl 91):1–17.CrossRefPubMedGoogle Scholar
  3. 3.
    Kopke RD, Hoffer ME, Wester D, O’Leary MJ, Jackson RL. Targeted topic steroid therapy in sudden sensorineural hearing loss. Otol Neurotol 2001;22:475–479.CrossRefPubMedGoogle Scholar
  4. 4.
    Gianoli GJ, Li JC. Transtympanic steroids for treatment of sudden hearing loss. Otolaryngol Head Neck Surg 2001; 125:142–146.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Jennifer J. Shin
    • 1
  • Steven D. Rauch
    • 2
  1. 1.Harvard Program in Otolaryngology-Head and Neck SurgeryMassachusetts Eye and Ear InfirmaryBostonUSA
  2. 2.Department of OtolaryngologyMassachusetts Eye and Ear InfirmaryBostonUSA

Personalised recommendations