Prodrugs pp 1305-1312 | Cite as

Case Study: Olmesartan Medoxomil: A Prodrug of Olmesartan

  • Bianca M. Liederer
Part of the Biotechnology: Pharmaceutical Aspects book series (PHARMASP, volume V)


Olmesartan is a durable, specific, and competitive nonpeptide angiotensin II receptor antagonist used to treat hypertension. To achieve better oral bioavailability its ester prodrug, olmesartan medoxomil, was developed. Olmesartan medoxomil is suitable for once daily oral administration and is available in tablet form.


Olmesartan Medoxomil Antihypertensive Efficacy Ambulatory Blood Pressure Measurement Ester Prodrug Daily Oral Administration 
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Copyright information

© American Association of Pharmaceutical Scientists 2007

Authors and Affiliations

  • Bianca M. Liederer
    • 1
  1. 1.Department of Pharmaceutical ChemistryThe University of KansasLawrenceUSA

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