Adjustment of Antimicrobial Regimen in Critically III Patients Undergoing Continuous Renal Replacement Therapy
Infection is a common problem in the intensive care unit (ICU). Severe sepsis and septic shock are conditions at the end of the spectrum of human response to infection. Acute renal failure is increasingly seen as part of the multiple organ dysfunction syndrome, which is the most frequent cause of death in patients admitted to the ICU. However, severe sepsis and septic shock are the primary causes of the multiple organ dysfunction syndrome. In the past decades, continuous renal replacement therapy (CRRT) has been widely employed as an extracorporeal blood purification method in the management of septic patients with or without acute renal failure in the ICU, because it offers several advantages over conventional intermitant hemodialysis and peritoneal dialysis .
KeywordsAcute Renal Failure Continuous Renal Replacement Therapy Multiple Organ Dysfunction Syndrome Drug Clearance Drug Removal
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