Abstract
The Japanese Consortium for an Artificial Retina has developed a new stimulating method named Suprachoroidal-Transretinal Stimulation (STS). Using STS, electrically evoked potentials (EEPs) were effectively elicited in Royal College of Surgeons (RCS) rats and in rabbits and cats with normal vision, using relatively small stimulus currents, such that the spatial resolution appeared to be adequate for a visual prosthesis. The histological analysis showed no damage to the rabbit retina when electrical currents sufficient to elicit distinct EEPs were applied. It was also shown that transcorneal electrical stimulation (TES) to the retina prevented the death of retinal ganglion cells (RGCs). STS, which is less invasive than other retinal prostheses, could be one choice to achieve artificial vision, and the optimal parameters of electrical stimulation may also be effective for the neuroprotection of residual RGCs.
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Fujikado, T., Sawai, H., Tano, Y. (2007). Artificial Vision: Vision of a Newcomer. In: Humayun, M.S., Weiland, J.D., Chader, G., Greenbaum, E. (eds) Artificial Sight. Biological and Medical Physics, Biomedical Engineering. Springer, New York, NY. https://doi.org/10.1007/978-0-387-49331-2_2
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