Multiple Roles for Hedgehog Signalling in Zebrafish Eye Development

Part of the Molecular Biology Intelligence Unit book series (MBIU)


The Hedgehog signalling pathway is important in a large number of developmental contexts. In this review, several functions of this pathway for vertebrate eye formation and differentiation will be discussed, with an emphasis on information derived from the zebrafish model. The highlighted roles for Hedgehog signalling include those in photoreceptor development, ganglion cell development, retinal cell proliferation and cell death, and the initiation of retinal neurogenesis.


Amacrine Cell Sonic Hedgehog Neural Retina Retinal Pigment Epithelium Retinal Progenitor Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Landes Bioscience and Springer Science+Business Media 2006

Authors and Affiliations

  1. 1.Department of Biological SciencesUniversity of IdahoMoscowUSA

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