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Multiple Roles for Hedgehog Signalling in Zebrafish Eye Development

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Shh and Gli Signalling and Development

Part of the book series: Molecular Biology Intelligence Unit ((MBIU))

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Abstract

The Hedgehog signalling pathway is important in a large number of developmental contexts. In this review, several functions of this pathway for vertebrate eye formation and differentiation will be discussed, with an emphasis on information derived from the zebrafish model. The highlighted roles for Hedgehog signalling include those in photoreceptor development, ganglion cell development, retinal cell proliferation and cell death, and the initiation of retinal neurogenesis.

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© 2006 Landes Bioscience and Springer Science+Business Media

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Stenkamp, D.L. (2006). Multiple Roles for Hedgehog Signalling in Zebrafish Eye Development. In: Shh and Gli Signalling and Development. Molecular Biology Intelligence Unit. Springer, New York, NY. https://doi.org/10.1007/978-0-387-39957-7_6

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