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Introduction

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Book cover Shh and Gli Signalling and Development

Part of the book series: Molecular Biology Intelligence Unit ((MBIU))

Abstract

Although no real insights into the mechanisms of development were obtained until after 1880, when experimental approaches to embryology were established, descriptive studies of embryo development have been around for millennia. Aristotle (384–322 BC) wrote a very detailed description of mammalian embryogenesis, similar to the picture we accept today, inferring that the process was driven by an entekch, known as a “vital force” in later centuries. Descriptive studies continued after 1550 but there was no further serious discussion of the mechanisms of embryo development until the 18th and 19th centuries.

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  1. Immunobiology Group, MRC/UoE Centre for Inflammation Research, The Queen’s Medical Research Institute, Little France Crescent, Edinburgh, EH16 4TJ, Scotland, UK

    Carolyn E. Fisher & Sarah E.M. Howie

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  1. Carolyn E. Fisher
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Fisher, C.E., Howie, S.E. (2006). Introduction. In: Shh and Gli Signalling and Development. Molecular Biology Intelligence Unit. Springer, New York, NY. https://doi.org/10.1007/978-0-387-39957-7_1

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