Part of the Molecular Biology Intelligence Unit book series (MBIU)


Although no real insights into the mechanisms of development were obtained until after 1880, when experimental approaches to embryology were established, descriptive studies of embryo development have been around for millennia. Aristotle (384–322 BC) wrote a very detailed description of mammalian embryogenesis, similar to the picture we accept today, inferring that the process was driven by an entekch, known as a “vital force” in later centuries. Descriptive studies continued after 1550 but there was no further serious discussion of the mechanisms of embryo development until the 18th and 19th centuries.


Congenital Diaphragmatic Hernia Sonic Hedgehog Imaginal Disc Congenital Diaphragmatic Hernia Floor Plate 
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Copyright information

© Landes Bioscience and Springer Science+Business Media 2006

Authors and Affiliations

  1. 1.Immunobiology Group, MRC/UoE Centre for Inflammation ResearchThe Queen’s Medical Research Institute, Little France CrescentEdinburghUK

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