Abstract
Squamous cell carcinoma of the upper aerodigestive tract represents 90% of all malignant neoplasms developing in the head and neck. The main risk factors are alcohol and tobacco, and their effects are multiplicative (1). The age-standardized incidence rate of head and neck cancer (around 1990) in males exceeds 30/100,000 in regions of France, Hong Kong, the Indian subcontinent, Central and Eastern Europe, Spain, Italy, Brazil, and among US blacks. In women, high rates (>10/100,000) are found in the Indian subcontinent, Hong Kong, and the Philippines. The tongue is the most common site in the oral cavity, followed by the floor of the mouth, lip, gingival and retromolar trigone (1).
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Calabrese, L., Soutar, D., Werner, J., Bruschini, R., De Cicco, C., Chiesa, F. (2008). Sentinel Lymph Node Biopsy in Cancer of the Head and Neck. In: Mariani, G., Giuliano, A.E., Strauss, H.W. (eds) Radioguided Surgery. Springer, New York, NY. https://doi.org/10.1007/978-0-387-38327-9_12
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DOI: https://doi.org/10.1007/978-0-387-38327-9_12
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