A Template-Based Mixed-Integer Linear Programming Sequence Alignment Model

  • Scott R. McAllister
  • Rohit Rajgaria
  • Christodoulos A. Floudas
Part of the Optimization and Its Applications book series (SOIA, volume 4)


The similarity of DNA or protein sequences between species is an approximate measure of the evolutionary distance between them. By identifying and aligning pairs of sequences, knowledge of the genetic importance of a gene or protein of one species can be extended to a second, relatively unknown species with a similar sequence.


Optimal Alignment Alignment Problem Bovine Pancreatic Trypsin Inhibitor Bovine Rhodopsin Pairwise Sequence Alignment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Scott R. McAllister
    • 1
  • Rohit Rajgaria
    • 1
  • Christodoulos A. Floudas
    • 1
  1. 1.Department of Chemical EngineeringPrinceton UniversityPrincetonUSA

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