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A Tribute to John Burden West

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Hypoxia and Exercise

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 588))

Abstract

John West is well known to the “Hypoxia” community for his many contributions to the physiology and Pathophysiology of high altitude and for his leadership of the 1981 American Medical Research Expedition to Everest. He is known to the wider medical world for his researches into respiratory physiology especially gas exchange in the lung and perhaps even more for his numerous books on these topics. His publication list numbers over 400 original papers. His research career started in the UK but since 1969 he has been Professor of Medicine at UCSD, leading a very productive team at La Jolla. He has been honoured by numerous prizes and named lectureships, the latest honour being to be elected to the Institute of Medicine, National Academies (USA).

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Selected References of John B. West

Books

  1. West, J.B. Respiratory Physiology-The Essentials. 7th edition. Philadelphia: Lippincott Williams & Wilkins, 2005.

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  2. West, J.B. Everest-The Testing Place. New York: McGraw-Hill, 1985.

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  3. West, J.B. High Life: A History of High-Altitude Physiology and Medicine. New York: Oxford University Press, 1998.

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Articles

  1. West, J.B. and C.T. Dollery. Distribution of blood flow and ventilation-perfusion ratio in the lung, measured with radioactive CO2. J. Appl. Physiol. 15: 405–410, 1960.

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  2. West, J.B. Diffusing capacity of the lung for carbon monoxide at high altitude. J. Appl. Physiol. 17: 421–426, 1962.

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  3. Pugh, L.G.C.E., M.B. Gill, S. Lahiri, J.S. Milledge, M.P. Ward, and J.B. West. Muscular exercise at great altitudes. J. Appl. Physiol. 19: 431–440, 1964.

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  4. West, J.B., C.T. Dollery and A. Naimark. Distribution of blood flow in isolated lung; relation to vascular and alveolar pressures. J. Appl. Physiol. 19: 713–724, 1964.

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  5. West, J.B. Ventilation-perfusion inequality and overall gas exchange in computer models of the lung. Resp. Physiol. 7: 88–110, 1969.

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  6. Wagner, P.D., H.A. Saltzman and J.B. West. Measurement of continuous distributions of ventilation-perfusion ratios: theory. J. Appl. Physiol. 36: 588–599, 1974.

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  7. West, J.B. and P.D. Wagner. Predicted gas exchange on the summit of Mt. Everest. Resp. Physiol. 42: 1–16, 1980.

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  8. West, J.B., PH. Hackett, K.H. Maret, J.S. Milledge, R.M. Peters, Jr., C.J. Pizzo and R.M. Winslow. Pulmonary gas exchange on the summit of Mt. Everest. J. Appl. Physiol.: Resp. Environ. Exercise Physiol. 55: 678–687, 1983.

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  9. West, J.B., S.J. Boyer, D.J. Graber, P.H. Hackett, K.H. Maret, J.S. Milledge, R.M. Peters, Jr., C.J. Pizzo, M. Samaja, F.H. Sarnquist, R.B. Schoene and R.M. Winslow. Maximal exercise at extreme altitudes on Mount Everest. J. Appl. Physiol.: Resp. Environ. Exercise Physiol. 55: 688–698, 1983.

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  10. Winslow, R.M., M. Samaja and J.B. West. Red cell function at extreme altitude on Mount Everest. J. Appl. Physiol.: Resp. Environ. Exercise Physiol. 56: 109–116, 1984.

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  11. West, J.B. Human physiology at extreme altitudes on Mount Everest. Science 223: 784–788, 1984.

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  12. West, J.B. Highest inhabitants in the world. Nature 324: 517, 1986.

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  13. West, J.B., K. Tsukimoto, O. Mathieu-Costello and R. Prediletto. Stress failure in pulmonary capillaries. J. Appl. Physiol. 70: 1731–1742, 1991.

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  14. Prisk, G.K., H.J.B. Guy, A.R. Elliott, R.A. Deutschman III and J.B. West. Pulmonary diffusing capacity, capillary blood volume and cardiac output during sustained microgravity. J. Appl. Physiol. 75: 15–26, 1993.

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  15. West, J.B., O. Mathieu-Costello, J.H. Jones, E.K. Birks, R.B. Logemann, J.R. Pascoe and W.S. Tyler. Stress failure of pulmonary capillaries in racehorses with exercise-induced pulmonary hemorrhage. J. Appl. Physiol. 75: 1097–1109, 1993.

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  16. West, J.B. Oxygen enrichment of room air to relieve the hypoxia of high altitude. Resp. Physiol. 99: 225–232, 1995.

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  17. West, J.B. Snorkel breathing in the elephant explains the unique anatomy of its pleura. Resp. Physiol. 126: 1–8, 2001.

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  18. West, J.B. Thoughts on the pulmonary blood-gas barrier. Am. J. Physiol.: Lung Cell. Mol. Physiol. 285: L501–L513, 2003.

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Milledge, J.S. (2006). A Tribute to John Burden West. In: Roach, R.C., Wagner, P.D., Hackett, P.H. (eds) Hypoxia and Exercise. Advances in Experimental Medicine and Biology, vol 588. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-34817-9_1

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