A Tribute to John Burden West

  • James S. Milledge
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 588)


John West is well known to the “Hypoxia” community for his many contributions to the physiology and Pathophysiology of high altitude and for his leadership of the 1981 American Medical Research Expedition to Everest. He is known to the wider medical world for his researches into respiratory physiology especially gas exchange in the lung and perhaps even more for his numerous books on these topics. His publication list numbers over 400 original papers. His research career started in the UK but since 1969 he has been Professor of Medicine at UCSD, leading a very productive team at La Jolla. He has been honoured by numerous prizes and named lectureships, the latest honour being to be elected to the Institute of Medicine, National Academies (USA).


biography gas exchange altitude physiology altitude pathology cardio-respiratory physiology space medicine 


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Selected References of John B. West


  1. 1.
    West, J.B. Respiratory Physiology-The Essentials. 7th edition. Philadelphia: Lippincott Williams & Wilkins, 2005.Google Scholar
  2. 2.
    West, J.B. Everest-The Testing Place. New York: McGraw-Hill, 1985.Google Scholar
  3. 3.
    West, J.B. High Life: A History of High-Altitude Physiology and Medicine. New York: Oxford University Press, 1998.Google Scholar


  1. 1.
    West, J.B. and C.T. Dollery. Distribution of blood flow and ventilation-perfusion ratio in the lung, measured with radioactive CO2. J. Appl. Physiol. 15: 405–410, 1960.PubMedGoogle Scholar
  2. 2.
    West, J.B. Diffusing capacity of the lung for carbon monoxide at high altitude. J. Appl. Physiol. 17: 421–426, 1962.PubMedGoogle Scholar
  3. 3.
    Pugh, L.G.C.E., M.B. Gill, S. Lahiri, J.S. Milledge, M.P. Ward, and J.B. West. Muscular exercise at great altitudes. J. Appl. Physiol. 19: 431–440, 1964.PubMedGoogle Scholar
  4. 4.
    West, J.B., C.T. Dollery and A. Naimark. Distribution of blood flow in isolated lung; relation to vascular and alveolar pressures. J. Appl. Physiol. 19: 713–724, 1964.PubMedGoogle Scholar
  5. 5.
    West, J.B. Ventilation-perfusion inequality and overall gas exchange in computer models of the lung. Resp. Physiol. 7: 88–110, 1969.CrossRefGoogle Scholar
  6. 6.
    Wagner, P.D., H.A. Saltzman and J.B. West. Measurement of continuous distributions of ventilation-perfusion ratios: theory. J. Appl. Physiol. 36: 588–599, 1974.PubMedGoogle Scholar
  7. 7.
    West, J.B. and P.D. Wagner. Predicted gas exchange on the summit of Mt. Everest. Resp. Physiol. 42: 1–16, 1980.CrossRefGoogle Scholar
  8. 8.
    West, J.B., PH. Hackett, K.H. Maret, J.S. Milledge, R.M. Peters, Jr., C.J. Pizzo and R.M. Winslow. Pulmonary gas exchange on the summit of Mt. Everest. J. Appl. Physiol.: Resp. Environ. Exercise Physiol. 55: 678–687, 1983.PubMedGoogle Scholar
  9. 9.
    West, J.B., S.J. Boyer, D.J. Graber, P.H. Hackett, K.H. Maret, J.S. Milledge, R.M. Peters, Jr., C.J. Pizzo, M. Samaja, F.H. Sarnquist, R.B. Schoene and R.M. Winslow. Maximal exercise at extreme altitudes on Mount Everest. J. Appl. Physiol.: Resp. Environ. Exercise Physiol. 55: 688–698, 1983.PubMedGoogle Scholar
  10. 10.
    Winslow, R.M., M. Samaja and J.B. West. Red cell function at extreme altitude on Mount Everest. J. Appl. Physiol.: Resp. Environ. Exercise Physiol. 56: 109–116, 1984.PubMedGoogle Scholar
  11. 11.
    West, J.B. Human physiology at extreme altitudes on Mount Everest. Science 223: 784–788, 1984.PubMedCrossRefGoogle Scholar
  12. 12.
    West, J.B. Highest inhabitants in the world. Nature 324: 517, 1986.PubMedCrossRefGoogle Scholar
  13. 13.
    West, J.B., K. Tsukimoto, O. Mathieu-Costello and R. Prediletto. Stress failure in pulmonary capillaries. J. Appl. Physiol. 70: 1731–1742, 1991.PubMedGoogle Scholar
  14. 14.
    Prisk, G.K., H.J.B. Guy, A.R. Elliott, R.A. Deutschman III and J.B. West. Pulmonary diffusing capacity, capillary blood volume and cardiac output during sustained microgravity. J. Appl. Physiol. 75: 15–26, 1993.PubMedGoogle Scholar
  15. 15.
    West, J.B., O. Mathieu-Costello, J.H. Jones, E.K. Birks, R.B. Logemann, J.R. Pascoe and W.S. Tyler. Stress failure of pulmonary capillaries in racehorses with exercise-induced pulmonary hemorrhage. J. Appl. Physiol. 75: 1097–1109, 1993.PubMedGoogle Scholar
  16. 16.
    West, J.B. Oxygen enrichment of room air to relieve the hypoxia of high altitude. Resp. Physiol. 99: 225–232, 1995.CrossRefGoogle Scholar
  17. 17.
    West, J.B. Snorkel breathing in the elephant explains the unique anatomy of its pleura. Resp. Physiol. 126: 1–8, 2001.CrossRefGoogle Scholar
  18. 18.
    West, J.B. Thoughts on the pulmonary blood-gas barrier. Am. J. Physiol.: Lung Cell. Mol. Physiol. 285: L501–L513, 2003.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • James S. Milledge
    • 1
  1. 1.International Society of Mountain MedicineHarrowUK

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