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Tissue Engineering pp 261–276Cite as

Non-Invasive Monitoring of Tissue-Engineered Pancreatic Constructs by NMR Techniques

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 585))

Abstract

Tissue engineering is an expanding field that combines the principles of engineering and the life sciences towards the fundamental understanding of structure/function relationships in normal and pathological mammalian tissues, and the development of biological substitutes to restore, maintain, or improve function (1). There are several critical issues that hamper the development of tissue engineered constructs. These include, but may not be limited to: (i) the source and function of cells employed within the constructs; (ii) the biomaterials used to build the constructs; (iii) the ability to scale up production to a medically relevant scale; (iv) the immune acceptance of a construct; (v) the preservation and subsequent off-the-shelf availability of the construct, and (vi) the ability to monitor the function and integrity of the construct in vivo. In this review we will focus on the issue of non-invasive monitoring.

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Author information

Authors and Affiliations

  1. University of Florida, Gainesville, FL, 32610, USA

    Stephen J. Blackband

  2. Emory University, Atlanta, GA, 30322, USA

    Robert C. Long Jr.

  3. Georgia Institute of Technology, Atlanta, GA, 30320, USA

    Athanassios Sambanis

  4. Department of Medicine, University of Florida, Gainesville, Florida, USA

    Ioannis Constantinidis, Nicholas E. Simpson & Samuel C. Grant

Authors
  1. Ioannis Constantinidis
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  2. Nicholas E. Simpson
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  3. Samuel C. Grant
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  4. Stephen J. Blackband
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  5. Robert C. Long Jr.
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  6. Athanassios Sambanis
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Editor information

Editors and Affiliations

  1. University of Maryland, College Park, MD, 20742, USA

    John P. Fisher

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Constantinidis, I., Simpson, N.E., Grant, S.C., Blackband, S.J., Long, R.C., Sambanis, A. (2006). Non-Invasive Monitoring of Tissue-Engineered Pancreatic Constructs by NMR Techniques. In: Fisher, J.P. (eds) Tissue Engineering. Advances in Experimental Medicine and Biology, vol 585. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-34133-0_18

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  • DOI: https://doi.org/10.1007/978-0-387-34133-0_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-32664-1

  • Online ISBN: 978-0-387-34133-0

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