5. Conclusions
The taurine-perfused isolated rat hearts recovered faster after normothermic 30-min ischemia induced while the hearts were beating. Lactic acid production was decreased and pyruvic acid production increased. The addition of taurine to St. Thomas Hospital cardioplegic solution decreased lactate and efflux of tissue injury markers, maintained CKMB activity and aerobic metabolism, and prevented DNA oxidation, markedly ameliorating LV function in the hearts stored cold for 6 hours
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Oriyanhan, W. et al. (2006). Taurine Addition to St Thomas’ Solution Prevents DNA Oxidative Stress and Maintains Contractile Function. In: Oja, S.S., Saransaari, P. (eds) Taurine 6. Advances in Experimental Medicine and Biology, vol 583. Springer, Boston, MA . https://doi.org/10.1007/978-0-387-33504-9_31
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