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The Nuclear Localization Signal of the Prrs Virus Nucleocapsid Protein Modulates Viral Replication in vitro and Antibody Response in vivo

  • Changhee Lee
  • Douglas C. Hodgins
  • Jay G. Calvert
  • Siao-Kun Wan Welch
  • Rika Jolie
  • Dongwan Yoo
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 581)

Keywords

Nuclear Localization Signal Nucleocapsid Protein Respiratory Syndrome Virus Nuclear Localization Signal Sequence Protein Nuclear Localization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Wootton, S., Rowland, R. R., and Yoo, D., 2002, Phosphorylation of the porcine reproductive and respiratory syndrome virus (PRRSV) nucleocapsid protein, J. Virol. 76:10569-10576.CrossRefPubMedGoogle Scholar
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    Wootton, S. K., and Yoo, D., 2003, Homo-oligomerization of the porcine reproductive and respiratory syndrome virus nucleocapsid protein and the role of disulfide linkages, J. Virol. 77:4546-4557.CrossRefPubMedGoogle Scholar
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    Lee, C., Calvert, J. G., Welch, S. W., and Yoo, D., 2005, A DNA-launched reverse genetics system for porcine reproductive and respiratory syndrome virus reveals that homodimerization of the nucleocapsid protein is essential for virus infectivity, Virology 331:47-62.CrossRefPubMedGoogle Scholar
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    Rowland, R. R., Kervin, R., Kuckleburg, C., Sperlich, A., and Benfield, D. A., 1999, The localization of porcine reproductive and respiratory syndrome virus nucleocapsid protein to the nucleolus of infected cells and identification of a potential nucleolar localization signal sequence, Virus Res. 64:1-12.CrossRefPubMedGoogle Scholar
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    Rowland, R. R., Schneider, P., Fang, Y., Wootton, S., Yoo, D., and Benfield, D. A., 2003, Peptide domains involved in the localization of the porcine reproductive and respiratory syndrome virus nucleocapsid protein to the nucleolus, Virology 316:135-145.CrossRefPubMedGoogle Scholar
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    Yoo, D., Wootton, S. K., Li, G., Song, C., and Rowland, R. R., 2003, Colocalization and interaction of the porcine arterivirus nucleocapsid protein with the small nucleolar RNA-associated protein fibrillarin, J. Virol. 77:12173-12183.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Changhee Lee
    • 1
  • Douglas C. Hodgins
    • 2
  • Jay G. Calvert
    • 3
  • Siao-Kun Wan Welch
    • 4
  • Rika Jolie
    • 5
  • Dongwan Yoo
    • 6
  1. 1.University of GuelphGuelphCanada
  2. 2.University of GuelphGuelphCanada
  3. 3.Pfizer Animal HealthKalamazooUSA
  4. 4.Pfizer Animal HealthKalamazooUSA
  5. 5.Pfizer Animal HealthKalamazooUSA
  6. 6.University of GuelphGuelphCanada

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