Abstract
Upon completion of the chapter, the student will be able to:
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1.
Differentiate between transient ischemic attack (TIA) and nonhemorrhagic and hemorrhagic stroke.
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2.
Understand the etiologies and diagnostic evaluation of stroke and cerebrovascular disease.
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3.
Appreciate the acute management, and primary and secondary preventive strategies in stroke.
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4.
Understand the principle behind the rehabilitation of the poststroke patient.
Material in this chapter is based on the following chapters in Cassel CK, Leipzig RM, Cohen HJ, Larson EB, Meier DE, eds. Geriatric Medicine: An Evidence-Based Approach, 4th ed. New York: Springer, 2003: Brummel-Smith K. Rehabilitation, pp. 259–277. Tuhrim S. Cerebrovascular Disease and Stroke, pp. 1123–1137. Selections edited by Daniel E. Wollman.
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Suggested Readings
Albers GW, Easton JD, Sacco RL, Teal P. Antithrombotic and thrombolytic therapy for ischemic stroke. Chest 1998;114:6385–6985. This paper provides an excellent overview of current treatment modalities in stroke.
Brummel-Smith K. Rehabilitation. In: Cassel CK, Leipzig RM, Cohen HJ, et al., eds. Geriatric Medicine, 4th ed. New York: Springer, 2003:259–277.
Fisher CM. Lacunar strokes and infarcts: a review. Neurology 1982;32:871–876. This is a classic paper describing much of what we continue to observe in the lacunar syndrome. Fisher also discusses the pathophysiology leading to small vessel thrombosis.
Gilman S. Medical progress: imaging the brain—first of two parts. N Engl J Med 1998;338:812–820.
Gilman S. Medical progress: imaging the brain—second of two parts. N Engl J Med 1998;338:889–896. These two papers provide an excellent overview of the appropriate use of neuroimaging in cerebrovascular disease and other neurological dysfunction.
Tuhrim S. Cerebrovascular disease and stroke. In: Cassel CK, Leipzig RM, Cohen HJ, et al., eds. Geriatric Medicine, 4th ed. New York: Springer, 2003:1123–1137.
References
American Heart Association. 1999 Heart and Stroke Statistical Update. Dallas: American Heart Association, 1998.
Murray CJL, Lopez AD. Mortality by cause for eight regions of the world: global burden of disease study. Lancet 1997;349:1269–1276.
Broderick J, Brott T, Kothari R, et al. The Greater Cincinnati/Northern Kentucky Stroke Study: preliminary first-ever and total incidence rates of stroke among blacks. Stroke 1998;29:415–421.
Gresham GE, Fitzpatrick TE, Wolf PA, et al. Residual disability in survivors of stroke—the Framingham Study. N Engl J Med 1975;293:954–956.
Black-Schaffer RM, Osberg JS. Return to work after stroke: development of a predictive model. Arch Phys Med Rehabil 1990;71:285–290.
Sacco RL, Boden-Albala B, Gan R, et al. Stroke incidence among white, black, and Hispanic residents of an urban community: the Northern Manhattan Stroke Study. Am J Epidemiol 1998;147:259–268.
Wolf PA, Abbott RD, Kannell AB. Atrial fibrillation as an independent risk factor for stroke: The Framingham Study. Stroke 1991;22:983–988.
Fisher CM. Lacunar strokes and infarcts: a review. Neurology 1982;32:871–876.
Bamford J, Sandercock P, Dennis M, Burn J, Warlow C. A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project—1981–86. 2. Incidence, case fatality rates and overall outcome at one year of cerebral infarction, primary intracerebral and subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry 1990;53:16–22.
Foulkes MA, Wolf PA, Price TR, Mohr JP, Hier DB. The Stroke Data Bank: design, methods, and baseline characteristics. Stroke 1988;19:547–554.
Gilbert JJ, Vinters HV. Cerebral Amyloid Angiopathy: incidence and complications in the aging brain. Stroke 1983;4:915–923.
Albers GW, Caplan LR, Easton JD, et al. Transient ischemic attack—proposal for a new definition. N Engl J Med 2002;347:1713–1716.
Roederer GO, Langlois YE, Jager KA, et al. The natural history of carotid arterial disease in asymptomatic patients with cervical bruits. Stroke 1984;15:605–613.
Caplan L. “Top of the basilar” syndrome. Neurology 1980;30:72–79.
Gilman S. Medical progress: imaging the brain—first of two parts. N Engl J Med 1998;338:812–820.
Gilman S. Medical progress: imaging the brain—second of two parts. N Engl J Med 1998;338:889–896.
Warach S, Dashe JF, Edelman RR. Clinical outcome in ischemic stroke predicted by early diffusion-weighted and perfusion magnetic resonance imaging: a preliminary analysis. J Cereb Blood Flow Metab 1996;16:53–59.
Alweiss GS, Goldman ME. Transesophageal echocardiography: diagnostic and clinical applications in the evaluation of the stroke patient. J Stroke Cerebrovasc Dis 1997;6:332–336.
Amarenco P, Cohen A, Tzoririo, et al. Atherosclerotic disease of the aortic-arch and the risk of ischemic stroke. N Engl J Med 1994;331:1474–1479.
Sacks FM, Svetkey LP, Vollmer WM, et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. N Engl J Med 2001;344:3–10.
Hacke W, Brott T, Caplan L, et al. Thrombolysis in acute ischemic stroke: controlled trials and clinical experience. Neurology 1999;53(suppl 7):S3–S14.
Furlan A, Higashida R, Wechsler L, et al. Intra-arterial prourokinase for acute ischemic stroke: The PROACT II study. JAMA 1999;282:2003–2011.
The International Stroke Trial (IST): a randomized trial of aspirin, subcutaneous heparin, both, or neither among 19,435 patients with acute ischemic stroke. Lancet 1997;349:1569–1581.
CAST (Chinese Acute Stroke Trial) Collaborative Group. CAST: randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischaemic stroke. Lancet 1997;349:1641–1649.
Adams HP, Bogousslavsky J, Baurathan E, et al. Abciximab in acute ischemic stroke—a randomized, double-blind, placebo-controlled, dose-escalation study. Stroke 2000;31:601–609.
Carlberg B, Asplund K, Hagg E. The prognostic value of admission blood pressure in patients with acute stroke. Stroke 1993;24:1372–1375.
Kuwata N, Kuroda K, Funayama M, Sato N, Kubo N, Ogawa A. Dysautoregulation in patients with hypertensive intracerebral hemorrhage. A SPECT study. Neurosurg Rev 1995;18:237–245.
Qureshi AI, Bliwise DL, Bliwise NG, Akbar MS, Uzen G, Frankel MR. Rate of 24-hour blood pressure decline and mortality after spontaneous intracerebral hemorrhage: a retrospective analysis with a random effects regression model. Crit Care Med 1999;27:480–485.
Broderick JP, Adams HP Jr, Barsan W, et al. Guidelines for the management of spontaneous intracerebral hemorrhage: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke 1999;30:905–915.
Tietjan CS, Hurn PD, Ulatowski JA, Kirsch JR. Treatment modalities for patients with intracranial pathology: options and risks. Crit Care Med 1996;24:311–322.
Goldstein LB. Should antihypertensive therapies be given to patients with acute ischemic stroke? Drug Saf 2000;22:13–18.
Lee J-M, Zipfel GJ, Choi DW. The changing landscape of ischaemic brain injury mechanisms. Nature 1999;399(suppl):A7–A14.
Albers GW, Easton JD, Sacco RL, Teal P. Antithrombotic and thrombolytic therapy for ischemic stroke. Chest 1998;114:6385–6985.
Dyken ML, Barnett HJ, Easton JD, Fields WS, Fuster V, et al. Low-dose aspirin and stroke. “It ain’t necessarily so.” Stroke 1992;23:1395–1399.
Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke in the Framingham Study. Stroke 1991;22:983–988.
Atrial Fibrillation Investigators. Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized trials. Arch Intern Med 1994;154:1449–1457.
Ezekowitz MD, Levine JA. Preventing stroke in patients with atrial fibrillation. JAMA 1999;281:1830–1835.
European Carotid Surgery Trialist’s Collaborative Group. MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70–99%) or with mild (0–19%) carotid stenosis. Lancet 1991;337:1235–1243.
North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in patients with high-grade carotid stenosis. N Engl J Med 1991;325:445–451.
Collaborative systematic review of the randomised trials of organised inpatient (stroke unit) care after stroke. Stroke Unit Trialists’ Collaboration. BMJ 1997;314:1151–1159.
Dombovy M, Sandok B, Basford J. Rehabilitation for stroke: a review. Stroke 1986;8:651–656.
Evans RL, Bishop DS, Haselkorn JK. Factors predicting satisfactory home care after a stroke. Arch Phys Med Rehabil 1991;72:144–147.
Kojima S, Omura T, Wakamatsu W, et al. Prognosis and disability of stroke patients after 5 years in Akita, Japan. Stroke 1990;21:72–77.
van de Weg FB, Kuik DJ, Lankhorst GJ. Post-stroke depression and functional outcome: a cohort study investigating the influence of depression on functional recovery from stroke. Clin Rehabil 1999;13:268–272.
Lazarus LW, Winemiller DR, Lingam VR, et al. Efficacy and side effects of methylphenidate for poststroke depression. J Clin Psychiatry 1992;53:447–449.
Burns A, Russell E, Stratton-Powell H, Tyrell P, O’Neill P, Baldwin R. Sertraline in stroke-associated liability of mood. Int J Geriatr Psychiatry 1999;14:681–685.
Mann G, Hankey GJ, Cameron D. Swallowing disorders following acute stroke: prevalence and diagnostic accuracy. Cerebrovasc Dis 2000;10:380–386.
Johnston MV, Wood K, Statson B, et al. Rehabilitative placement of post stroke patients—reliability of the clinical practice guideline of the Agency for Health Care Policy and Research. Arch Phys Med Rehabil 2000:81:539–548.
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Wollman, D.E. (2007). Transient Ischemic Attack and Stroke. In: Soriano, R.P., Fernandez, H.M., Cassel, C.K., Leipzig, R.M. (eds) Fundamentals of Geriatric Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-32326-8_15
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