Abstract
Classical Alport’s syndrome is an X-linked disease and is the most common form of Alport’s syndrome (90% of patients), with an overall incidence of Alport’s syndrome in the United States of 1 : 5000 to 1 : 10,000 (1–4). Patients show hematuria in childhood with progressive hearing loss in one third, and ocular defects and progression to renal failure in 30% to 40% by early adulthood. Anterior lenticonus is the most common eye defect.
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Fogo, A.B. (2006). Thin Basement Membranes and Alport’s Syndrome. In: Fogo, A.B., Cohen, A.H., Jennette, J.C., Bruijn, J.A., Colvin, R.B. (eds) Fundamentals of Renal Pathology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-31127-2_7
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DOI: https://doi.org/10.1007/978-0-387-31127-2_7
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