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Early Research on Brain Mechanisms of Sleep and Waking

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Abstract

During the final years of World War I and for a short time thereafter (1917–1919), a worldwide influenza epidemic was caused by one of the most deadly viruses ever known. The disease had a number of names, the best known being the Spanish flu. It has been estimated that between 25 and 40 million fatalities were due to the influenza epidemic—many more than the 9 million killed by the war. A variant of the disease was encephalitis lethargica, in which victims entered a coma that usually ended in death. Some of those who survived entered a rigid Parkinson-like state that was dramatically described by the neurologist Oliver Sacks, in his book Awakenings (1973), and strikingly portrayed in a Hollywood film of the same name.

Keywords

Brain Stem Brain Mechanism Anterior Hypothalamus Encephalitis Lethargica Mesencephalic Reticular Formation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York, Inc. 2002

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