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Rotary Motor

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Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)

Abstract

The structure of the rotary motor was described in Chapter 9 (Fig. 9.3) and its assembly was discussed in Chapter 10. Here, I will say more about function. Given that the diameter of the motor is less than one-tenth the wavelength of light and that it contains more than 20 of different kinds of parts (Appendix, Table A.3), it is a nanotechnologist’s dream (or nightmare).

Keywords

Duty Ratio Latex Bead Load Line Rotary Motor Torque Generator 
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References

  1. Asai, Y., T. Yakushi, I. Kawagishi, and M. Homma. 2003. Ion-coupling determinants of Na+-driven and H+-driven flagellar motors. J. Mol. Biol. 327:453–463.CrossRefGoogle Scholar
  2. Berg, H. C. 1976. Does the flagellar rotary motor step? In: Cell Motility, Cold Spring Harbor Conferences on Cell Proliferation. R. Goldman, T. Pollard, J. Rosenbaum, editors. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY., pp. 47–56.Google Scholar
  3. Berg, H. C. 2000. Constraints on models for the flagellar rotary motor. Philos. Trans. R. Soc. Lond. B 355:491–501.CrossRefGoogle Scholar
  4. Berg, H. C. 2003. The rotary motor of bacterial flagella. Anna. Rev. Biochem, 72:19–54.CrossRefGoogle Scholar
  5. Berg, H. C., and L. Turner. 1979. Movement of microorganisms in viscous environments. Nature 278:349–351.CrossRefADSGoogle Scholar
  6. Berg, H. C., and L. Turner. 1993. Torque generated by the flagellar motor of Escherichia coli. Biophys. J. 65:2201–2216.ADSCrossRefGoogle Scholar
  7. Berry, R. B. 2000. Theories of rotary motors. Philos. Trans. R. Soc. Lond. B 355:503–509.CrossRefGoogle Scholar
  8. Berry, R. B. 2003. The bacterial flagellar motor. In: Molecular Motors. M. Schliwa, editor. Wiley-VCH, Weinheim, pp. 111–140.Google Scholar
  9. Berry, R. B., and J. P. Armitage. 1999. The bacterial flagella motor. Adv. Microbiol. Physiol. 41:291–337.CrossRefGoogle Scholar
  10. Berry, R. M., and H. C. Berg. 1997. Absence of a barrier to backwards rotation of the bacterial flagellar motor demonstrated with optical tweezers. Proc. Natl. Acad. Sci. USA 94:14433–14437.CrossRefADSGoogle Scholar
  11. Berry, R. M., and H. C. Berg. 1999. Torque generated by the flagellar motor of Escherichia coli while driven backward. Biophys. J. 76: 580–587.CrossRefADSGoogle Scholar
  12. Blair, D. F. 2003. Flagellar movement driven by proton translocation. FEBS Lett. 545:86–95.CrossRefGoogle Scholar
  13. Blair, D. F., and H. C. Berg. 1988. Restoration of torque in defective flagellar motors. Science 242:1678–1681.CrossRefADSGoogle Scholar
  14. Block, S. M., D. F. Blair, and H. C. Berg. 1989. Compliance of bacterial flagella measured with optical tweezers. Nature 338:514–517.CrossRefADSGoogle Scholar
  15. Braun, T. F., and Blair, D. F. 2001. Targeted disulfide cross-linking of the MotB protein of Escherichia coli: evidence for two H+ channels in the stator complex. Biochemistry 40:13051–13059.CrossRefGoogle Scholar
  16. Braun, T. F., S. Poulson, J. B. Gully, et al. 1999. Function of proline residues of MotA in torque generation by the flagellar motor of Escherichia coli. J. Bacteriol. 181:3542–3551. Bustamante, C., D. Keller, and G. Oster. 2001. The physics of molecular motors. Acc. Chem. Res. 34:412–420.Google Scholar
  17. Caplan, S. R., and M. Kara-Ivanov. 1993. The bacterial flagellar motor. Int. Rev. Cytol. 147:97–164.CrossRefGoogle Scholar
  18. Chen, X., and H. C. Berg. 2000a. Torque-speed relationship of the flagellar rotary motor of Escherichia coli. Biophys. J. 78:1036–1041.ADSCrossRefGoogle Scholar
  19. Chen, X., and H. C. Berg. 2000b. Solvent-isotope and pH effects on flagellar rotation in Escherichia coli. Biophys. J. 78:2280–2284.ADSCrossRefGoogle Scholar
  20. Fung, D. C., and H. C. Berg. 1995. Powering the flagellar motor of Escherichia coli with an external voltage source. Nature 375:809–812.CrossRefADSGoogle Scholar
  21. Gabel, C.V., and H. C. Berg. 2003. The speed of the flagellar rotary motor of Escherichia coli varies linearly with protonmotive force. Proc. Natl. Acad. Sci. USA 100:8748–8751.CrossRefADSGoogle Scholar
  22. Garcia de la Torre, J., and V. A. Bloomfield. 1981. Hydrodynamic properties of complex, rigid, biological macromolecules: theory and applications. Q. Rev. Biophys. 14:81–139.CrossRefGoogle Scholar
  23. Harold, F. M., and P. C. Maloney. 1996. Energy transduction by ion currents. In: Escherichia coli and Salmonella: Cellular and Molecular Biology. F. C. Neidhardt, R. Curtiss, J. L. Ingraham, et al., editors. ASM Press, Washington DC, pp. 283–306.Google Scholar
  24. Howard, J. 2001. Mechanics of Motor Proteins and the Cytoskeleton. Sinaur Associates, Sunderland, MA.Google Scholar
  25. Imae, Y. 1991. Use of Na+ as an alternative to H+ in energy transduction. In: New Era of Bioenergetics. Y. Mukohata, editor. Academic Press, Tokyo, pp. 197–221.Google Scholar
  26. Imae, Y., and T. Atsumi. 1989. Na+-driven bacterial flagellar motors. J. Bioenerg. Biomembr. 21:705–716.CrossRefGoogle Scholar
  27. Jeffery, G. B. 1915. On the steady rotation of a solid of revolution in a viscous fluid. Proc. Lond. Math. Soc. 14:327–338.Google Scholar
  28. Khan, S. 1997. Rotary chemiosmotic machines. Biochim. Biophys. Acta 1322:86–105.CrossRefGoogle Scholar
  29. Khan, S., and H. C. Berg. 1983. Isotope and thermal effects in chemiosmotic coupling to the flagellar motor of Streptococcus. Cell 32:913–919.CrossRefGoogle Scholar
  30. Khan, S., M. Meister, and H. C. Berg. 1985. Constraints on flagellar rotation. J. Mol. Biol. 184:645–656.CrossRefGoogle Scholar
  31. Kojima, S., and D. F. Blair 2001. Conformational change in the stator of the bacterial flagellar motor. Biochemistry 40:13041–13050.CrossRefGoogle Scholar
  32. Larsen, S. H., J. Adler, J. J. Gargus, and R. W. Hogg. 1974. Chemomechanical coupling without ATP: the source of energy for motility and chemotaxis in bacteria. Proc. Natl. Acad. Sci. USA 71:1239–1243.CrossRefADSGoogle Scholar
  33. Läuger, P., and B. Kleutsch. 1990. Microscopic models of the bacterial flagellar motor. Comments Theor. Biol. 2:99–123.Google Scholar
  34. Lloyd, S. A., and D. F. Blair. 1997. Charged residues of the rotor protein FliG essential for torque generation in the flagellar motor of Escherichia coli. J. Mol. Biol. 266:733–744.CrossRefGoogle Scholar
  35. Lowe, G., M. Meister, and H. C. Berg. 1987. Rapid rotation of flagellar bundles in swimming bacteria. Nature 325:637–640.CrossRefADSGoogle Scholar
  36. Macnab, R. M. 1996. Flagella and motility. In: Escherichia coli and Salmonella: Cellular and Molecular Biology. F. C. Neidhardt, R. Curtiss, J. L. Ingraham, et al., editors. ASM Press, Washington, DC, pp. 123–145.Google Scholar
  37. McCarter, L. L. 2001. Polar flagellar motility of the Vibrionaceae. Microbiol. Mol. Biol. Rev. 65:445–462.Google Scholar
  38. Meister, M., G. Lowe, and H. C. Berg. 1987. The proton flux through the bacterial flagellar motor. Cell 49:643–650.CrossRefGoogle Scholar
  39. Ravid, S., and M. Eisenbach. 1984. Minimal requirements for rotation of bacterial flagella. J. Bacteriol. 158:1208–1210.Google Scholar
  40. Samuel, A. D.T., and H. C. Berg. 1995. Fluctuation analysis of rotational speeds of the bacterial flagellar motor. Proc. Natl. Acad. Sci. USA 92: 3502–3506.CrossRefADSGoogle Scholar
  41. Samuel, A. D. T., and H. C. Berg. 1996. Torque-generating units of the bacterial flagellar motor step independently. Biophys. J. 71:918–923.ADSCrossRefGoogle Scholar
  42. Schuster, S. C., and S. Khan. 1994. The bacterial flagellar motor. Annu. Rev. Biophys. Biomol. Struct. 23:509–539.CrossRefGoogle Scholar
  43. van der Drift, C., J. Duiverman, H. Bexkens, and A. Krijnen. 1975. Chemotaxis of a motile Streptococcus toward sugars and amino acids. J. Bacteriol. 124:1142–1147.Google Scholar
  44. Washizu, M., Y. Kurahashi, H. Iochi, et al. 1993. Dielectrophoretic measurement of bacterial motor characteristics. IEEE Trans. Ind. Appl. 29:286–294.CrossRefGoogle Scholar
  45. Yorimitsu, T., and M. Homma. 2001. Na+-driven flagellar motor of Vibrio. Biochim. Biophys. Acta 1505:82–93.CrossRefGoogle Scholar
  46. Zhou, J., S. A. Lloyd, and D. F Blair. 1998a. Electrostatic interactions between rotor and stator in the bacterial flagellar motor. Proc. Natl. Acad. Sci. USA 95:6436–6441.CrossRefADSGoogle Scholar
  47. Zhou, J., L. L. Sharp, H. L. Tang, et al. 1998b. Function of protonatable residues in the flagellar motor of Escherichia coli: a critical role for Asp 32 of MotB. J. Bacteriol. 180:2729–2735.Google Scholar

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