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Rotary Motor

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E. coli in Motion

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

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Abstract

The structure of the rotary motor was described in Chapter 9 (Fig. 9.3) and its assembly was discussed in Chapter 10. Here, I will say more about function. Given that the diameter of the motor is less than one-tenth the wavelength of light and that it contains more than 20 of different kinds of parts (Appendix, Table A.3), it is a nanotechnologist’s dream (or nightmare).

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References

  • Asai, Y., T. Yakushi, I. Kawagishi, and M. Homma. 2003. Ion-coupling determinants of Na+-driven and H+-driven flagellar motors. J. Mol. Biol. 327:453–463.

    Article  Google Scholar 

  • Berg, H. C. 1976. Does the flagellar rotary motor step? In: Cell Motility, Cold Spring Harbor Conferences on Cell Proliferation. R. Goldman, T. Pollard, J. Rosenbaum, editors. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY., pp. 47–56.

    Google Scholar 

  • Berg, H. C. 2000. Constraints on models for the flagellar rotary motor. Philos. Trans. R. Soc. Lond. B 355:491–501.

    Article  Google Scholar 

  • Berg, H. C. 2003. The rotary motor of bacterial flagella. Anna. Rev. Biochem, 72:19–54.

    Article  Google Scholar 

  • Berg, H. C., and L. Turner. 1979. Movement of microorganisms in viscous environments. Nature 278:349–351.

    Article  ADS  Google Scholar 

  • Berg, H. C., and L. Turner. 1993. Torque generated by the flagellar motor of Escherichia coli. Biophys. J. 65:2201–2216.

    Article  ADS  Google Scholar 

  • Berry, R. B. 2000. Theories of rotary motors. Philos. Trans. R. Soc. Lond. B 355:503–509.

    Article  Google Scholar 

  • Berry, R. B. 2003. The bacterial flagellar motor. In: Molecular Motors. M. Schliwa, editor. Wiley-VCH, Weinheim, pp. 111–140.

    Google Scholar 

  • Berry, R. B., and J. P. Armitage. 1999. The bacterial flagella motor. Adv. Microbiol. Physiol. 41:291–337.

    Article  Google Scholar 

  • Berry, R. M., and H. C. Berg. 1997. Absence of a barrier to backwards rotation of the bacterial flagellar motor demonstrated with optical tweezers. Proc. Natl. Acad. Sci. USA 94:14433–14437.

    Article  ADS  Google Scholar 

  • Berry, R. M., and H. C. Berg. 1999. Torque generated by the flagellar motor of Escherichia coli while driven backward. Biophys. J. 76: 580–587.

    Article  ADS  Google Scholar 

  • Blair, D. F. 2003. Flagellar movement driven by proton translocation. FEBS Lett. 545:86–95.

    Article  Google Scholar 

  • Blair, D. F., and H. C. Berg. 1988. Restoration of torque in defective flagellar motors. Science 242:1678–1681.

    Article  ADS  Google Scholar 

  • Block, S. M., D. F. Blair, and H. C. Berg. 1989. Compliance of bacterial flagella measured with optical tweezers. Nature 338:514–517.

    Article  ADS  Google Scholar 

  • Braun, T. F., and Blair, D. F. 2001. Targeted disulfide cross-linking of the MotB protein of Escherichia coli: evidence for two H+ channels in the stator complex. Biochemistry 40:13051–13059.

    Article  Google Scholar 

  • Braun, T. F., S. Poulson, J. B. Gully, et al. 1999. Function of proline residues of MotA in torque generation by the flagellar motor of Escherichia coli. J. Bacteriol. 181:3542–3551. Bustamante, C., D. Keller, and G. Oster. 2001. The physics of molecular motors. Acc. Chem. Res. 34:412–420.

    Google Scholar 

  • Caplan, S. R., and M. Kara-Ivanov. 1993. The bacterial flagellar motor. Int. Rev. Cytol. 147:97–164.

    Article  Google Scholar 

  • Chen, X., and H. C. Berg. 2000a. Torque-speed relationship of the flagellar rotary motor of Escherichia coli. Biophys. J. 78:1036–1041.

    Article  ADS  Google Scholar 

  • Chen, X., and H. C. Berg. 2000b. Solvent-isotope and pH effects on flagellar rotation in Escherichia coli. Biophys. J. 78:2280–2284.

    Article  ADS  Google Scholar 

  • Fung, D. C., and H. C. Berg. 1995. Powering the flagellar motor of Escherichia coli with an external voltage source. Nature 375:809–812.

    Article  ADS  Google Scholar 

  • Gabel, C.V., and H. C. Berg. 2003. The speed of the flagellar rotary motor of Escherichia coli varies linearly with protonmotive force. Proc. Natl. Acad. Sci. USA 100:8748–8751.

    Article  ADS  Google Scholar 

  • Garcia de la Torre, J., and V. A. Bloomfield. 1981. Hydrodynamic properties of complex, rigid, biological macromolecules: theory and applications. Q. Rev. Biophys. 14:81–139.

    Article  Google Scholar 

  • Harold, F. M., and P. C. Maloney. 1996. Energy transduction by ion currents. In: Escherichia coli and Salmonella: Cellular and Molecular Biology. F. C. Neidhardt, R. Curtiss, J. L. Ingraham, et al., editors. ASM Press, Washington DC, pp. 283–306.

    Google Scholar 

  • Howard, J. 2001. Mechanics of Motor Proteins and the Cytoskeleton. Sinaur Associates, Sunderland, MA.

    Google Scholar 

  • Imae, Y. 1991. Use of Na+ as an alternative to H+ in energy transduction. In: New Era of Bioenergetics. Y. Mukohata, editor. Academic Press, Tokyo, pp. 197–221.

    Google Scholar 

  • Imae, Y., and T. Atsumi. 1989. Na+-driven bacterial flagellar motors. J. Bioenerg. Biomembr. 21:705–716.

    Article  Google Scholar 

  • Jeffery, G. B. 1915. On the steady rotation of a solid of revolution in a viscous fluid. Proc. Lond. Math. Soc. 14:327–338.

    Google Scholar 

  • Khan, S. 1997. Rotary chemiosmotic machines. Biochim. Biophys. Acta 1322:86–105.

    Article  Google Scholar 

  • Khan, S., and H. C. Berg. 1983. Isotope and thermal effects in chemiosmotic coupling to the flagellar motor of Streptococcus. Cell 32:913–919.

    Article  Google Scholar 

  • Khan, S., M. Meister, and H. C. Berg. 1985. Constraints on flagellar rotation. J. Mol. Biol. 184:645–656.

    Article  Google Scholar 

  • Kojima, S., and D. F. Blair 2001. Conformational change in the stator of the bacterial flagellar motor. Biochemistry 40:13041–13050.

    Article  Google Scholar 

  • Larsen, S. H., J. Adler, J. J. Gargus, and R. W. Hogg. 1974. Chemomechanical coupling without ATP: the source of energy for motility and chemotaxis in bacteria. Proc. Natl. Acad. Sci. USA 71:1239–1243.

    Article  ADS  Google Scholar 

  • Läuger, P., and B. Kleutsch. 1990. Microscopic models of the bacterial flagellar motor. Comments Theor. Biol. 2:99–123.

    Google Scholar 

  • Lloyd, S. A., and D. F. Blair. 1997. Charged residues of the rotor protein FliG essential for torque generation in the flagellar motor of Escherichia coli. J. Mol. Biol. 266:733–744.

    Article  Google Scholar 

  • Lowe, G., M. Meister, and H. C. Berg. 1987. Rapid rotation of flagellar bundles in swimming bacteria. Nature 325:637–640.

    Article  ADS  Google Scholar 

  • Macnab, R. M. 1996. Flagella and motility. In: Escherichia coli and Salmonella: Cellular and Molecular Biology. F. C. Neidhardt, R. Curtiss, J. L. Ingraham, et al., editors. ASM Press, Washington, DC, pp. 123–145.

    Google Scholar 

  • McCarter, L. L. 2001. Polar flagellar motility of the Vibrionaceae. Microbiol. Mol. Biol. Rev. 65:445–462.

    Google Scholar 

  • Meister, M., G. Lowe, and H. C. Berg. 1987. The proton flux through the bacterial flagellar motor. Cell 49:643–650.

    Article  Google Scholar 

  • Ravid, S., and M. Eisenbach. 1984. Minimal requirements for rotation of bacterial flagella. J. Bacteriol. 158:1208–1210.

    Google Scholar 

  • Samuel, A. D.T., and H. C. Berg. 1995. Fluctuation analysis of rotational speeds of the bacterial flagellar motor. Proc. Natl. Acad. Sci. USA 92: 3502–3506.

    Article  ADS  Google Scholar 

  • Samuel, A. D. T., and H. C. Berg. 1996. Torque-generating units of the bacterial flagellar motor step independently. Biophys. J. 71:918–923.

    Article  ADS  Google Scholar 

  • Schuster, S. C., and S. Khan. 1994. The bacterial flagellar motor. Annu. Rev. Biophys. Biomol. Struct. 23:509–539.

    Article  Google Scholar 

  • van der Drift, C., J. Duiverman, H. Bexkens, and A. Krijnen. 1975. Chemotaxis of a motile Streptococcus toward sugars and amino acids. J. Bacteriol. 124:1142–1147.

    Google Scholar 

  • Washizu, M., Y. Kurahashi, H. Iochi, et al. 1993. Dielectrophoretic measurement of bacterial motor characteristics. IEEE Trans. Ind. Appl. 29:286–294.

    Article  Google Scholar 

  • Yorimitsu, T., and M. Homma. 2001. Na+-driven flagellar motor of Vibrio. Biochim. Biophys. Acta 1505:82–93.

    Article  Google Scholar 

  • Zhou, J., S. A. Lloyd, and D. F Blair. 1998a. Electrostatic interactions between rotor and stator in the bacterial flagellar motor. Proc. Natl. Acad. Sci. USA 95:6436–6441.

    Article  ADS  Google Scholar 

  • Zhou, J., L. L. Sharp, H. L. Tang, et al. 1998b. Function of protonatable residues in the flagellar motor of Escherichia coli: a critical role for Asp 32 of MotB. J. Bacteriol. 180:2729–2735.

    Google Scholar 

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(2004). Rotary Motor. In: Berg, H.C. (eds) E. coli in Motion. Biological and Medical Physics, Biomedical Engineering. Springer, New York, NY. https://doi.org/10.1007/978-0-387-21638-6_12

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  • DOI: https://doi.org/10.1007/978-0-387-21638-6_12

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-00888-2

  • Online ISBN: 978-0-387-21638-6

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