The endemic treponematoses are a group of chronic diseases affecting primarily the skin of children and young adults who live in remote, impoverished areas between the tropics of Cancer and Capricorn. They are considered as a group because they have many clinical, pathological, and epidemiological features in common (see Table 1). They are also caused by spirochetes that are closely related to one another and to Treponema pallidum subsp. pallidum of venereal syphilis.(1) These diseases with their etiologic treponeme in order of their worldwide prevalence are yaws (T. pallidum subsp. pertenue), endemic syphilis (T. pallidum subsp. endemicum), and pinta (Treponema carateum).
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The authors would like to thank Peter L. Perine, MD, who passed away in 2003, for the initial groundwork of this chapter.
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Ahmed, A.M., Madkan, V., Brantley, J.S., Mendoza, N., Tyring, S.K. (2009). Syphilis. In: Brachman, P., Abrutyn, E. (eds) Bacterial Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-09843-2_37
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