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Proteases and Their Cognate Inhibitors of the Serine and Metalloprotease Subclasses, in Testicular Physiology

  • Brigitte Le Magueresse-BattistoniEmail author
Part of the Advances in Experimental Medicine and Biology book series (volume 636)

Abstract

The testis is a highly dynamic organ not only in the fetal stage but also during postnatal development and in adult life. It is composed of two major compartments: the interstitium with the steroidogenic Leydig cells, and the seminiferous tubules. The seminiferous tubules are surrounded by peritubular cells. Tubules are composed of Sertoli cells and germ cells at different developmental stages. Sertoli cells play key roles in spermatogenesis. They are target cells for follicle stimulating hormone (FSH) and testosterone, responsible for the initiation and maintenance of spermatogenesis. They form the tubules and provide structural and nutritional support for the developing germ cells1, 2, 3, 4.

Keywords

Germ Cell Plasminogen Activator Follicle Stimulate Hormone Sertoli Cell Leydig Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Landes Bioscience and Springer Science+Business Media 2009

Authors and Affiliations

  1. 1.Inserm U418 and INRA UMR 1245 and Université Lyon 1Hopital DebrousseLyon cedex 05France

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