Transcription Regulation in Spermatogenesis

  • Wing-Yee LuiEmail author
  • C. Yan Cheng
Part of the Advances in Experimental Medicine and Biology book series (volume 636)


Spermatogenesis is a highly coordinated process in which diploid spermatogonia (2n) differentiate into mature haploid (1n) spermatozoa in the seminiferous epithelium. In this process, spermatogonia undergo several mitotic divisions and either enter a stem cell renewal pathway, or commit themsevles for further development. Diploid spermatocytes subsequently undergo two meiotic divisions and result in the production of haploid round spermatids. They then enter the process of spermiogenesis in which profound morphological and biochemical restructuring, such as the formation of acrosome and flagellum occur, and give rise to mature spermatozoa.


Germ Cell Androgen Receptor Sertoli Cell Retinoic Acid Receptor Male Germ Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Landes Bioscience and Springer Science+Business Media 2009

Authors and Affiliations

  1. 1.School of Biological SciencesThe University of Hong KongHong KongChina
  2. 2.Center for Biomedical ResearchThe Population CouncilNew YorkUSA

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