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References
Birch, J. M., A. L. Hartley, et al. (1994). “Prevalence and diversity of constitutional mutations in the p53 gene among 21 Li–Fraumeni families.”Cancer Res 54(5): 1298–304.
Birch, J. M., V. Blair, et al. (1998). “Cancer phenotype correlates with constitutional TP53 genotype in families with the Li–Fraumeni syndrome.”Oncogene 17(9): 1061–8.
Bougeard, G., L. Brugieres, et al. (2003). “Screening for TP53 rearrangements in families with the Li–Fraumeni syndrome reveals a complete deletion of the TP53 gene.”Oncogene 22(6): 840–6.
Fisher, D. E. (2001). “The p53 tumor suppressor: critical regulator of life & death in cancer.”Apoptosis 6(1–2): 7–15.
Garber, J. E., A. M. Goldstein, et al. (1991). “Follow-up study of twenty-four families with Li–Fraumeni syndrome.”Cancer Res 51(22): 6094–7.
Hisada, M., J. E. Garber, et al. (1998). “Multiple primary cancers in families with Li–Fraumeni syndrome.”J Natl Cancer Inst 90(8): 606–11.
Hwang, S. J., G. Lozano, et al. (2003). “Germline p53 mutations in a cohort with childhood sarcoma: sex differences in cancer risk.”Am J Hum Genet 72(4): 975–83.
Kleihues, P., B. Schauble, et al. (1997). “Tumors associated with p53 germline mutations: a synopsis of 91 families.”Am J Pathol 150(1): 1–13.
Lane, D. P. (1992). “Cancer. p53, guardian of the genome.”Nature358(6381): 15–6.
Levine, A. J. (1997). “p53, the cellular gatekeeper for growth and division.”Cell 88(3): 323–31.
Li, F. P. and J. F. Fraumeni, Jr. (1969). “Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?”Ann Intern Med 71(4): 747–52.
Lynch, H. T. and A. de la Chapelle (1999). “Genetic susceptibility to non-polyposis colorectal cancer.”J Med Genet 36(11): 801–18.
Lynch, H. T. and A. de la Chapelle (2003). “Hereditary colorectal cancer.”N Engl J Med 348(10): 919–32.
Malkin, D., F. P. Li, et al. (1990). “Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms.”Science 250(4985): 1233–8.
Nichols, K. E., D. Malkin, et al. (2001). “Germ-line p53 mutations predispose to a wide spectrum of early-onset cancers.”Cancer Epidemiol Biomarkers Prev 10(2): 83–7.
Olivier, M., D. E. Goldgar, et al. (2003). “Li–Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype.”Cancer Res 63(20): 6643–50.
Varley, J. M., G. McGown, et al. (1995). “An extended Li–Fraumeni kindred with gastric carcinoma and a codon 175 mutation in TP53.”J Med Genet 32(12): 942–5.
Varley, J. M., D. G. Evans, et al. (1997). “Li–Fraumeni syndrome – a molecular and clinical review.”Br J Cancer 76(1): 1–14.
Walsh, T., S. Casadei, et al. (2006). “Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer.”JAMA 295(12): 1379–88.
Wong, P., S. J. Verselis, et al. (2006). “Prevalence of early onset colorectal cancer in 397 patients with classic Li–Fraumeni syndrome.”Gastroenterology 130(1): 73–9.
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Masciari, S., Syngal, S. (2009). The Role of p53 in Colorectal Cancer. In: Potter, J.D., Lindor, N.M. (eds) Genetics of Colorectal Cancer. Cancer Genetics. Springer, New York, NY. https://doi.org/10.1007/978-0-387-09568-4_14
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