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Agarwal VR, Takayama K, Van Wyk JJ, et al. Molecular basis of severe gynecomastia associated with aromatase expression in fibrolamellar hepatocellular carcinoma. J Clin Endocrinol Metab 1998;83:1797–1800
Andreu V, Elizalde I, Mallafre C, et al. Plexiform neurofibromatosis and angiosarcoma of the liver in von Recklinghausen Disease. Am J Gastroenterol 1997;92:1229–1230
Baker ME, Paulson EK. Hepatic metastatic disease. In: Meyers MA (ed): Neoplasms of the Digestive Tract: Imaging, Staging and Management. Philadelphia: Lippincott-Raven; 1998:361–395
Bartolozzi C, Cioni D, Donati F, et al. Focal liver lesions: MR imaging-pathologic correlation. Eur Radiol 2001;11:1374–1388
Basilico R, Blomley MJ, Harvey CJ, et al. Which continuous US scanning mode is optimal for the detection of vascularity in liver lesions when enhanced with a second generation contrast agent? Eur J Radiol 2002;41:184–191
Berman MM, Libbey NP, Foster JH. Hepatocellular carcinoma. Polygonal cell type with fibrous stroma — an atypical variant with a favorable prognosis. Cancer 1980;46:1448–1455
Biemer JJ. Hepatic manifestation of lymphomas. Ann Clin Lab Sci1984;14:252–260
Bluemke DA, Soyer P, Fishman E. Helical (spiral) CT of the liver. Radiol Clin North Am 1995;33:863–886
Brady J, Liberatore F, Harper P, et al. Angiosarcoma of the liver: an epidemiology survey. J Natl Cancer Inst 1977;59:1383–1385
Brandt DJ, Johnson CD, Stephens DH, et al. Imaging of fibrolamellar hepatocellular carcinoma. AJR Am J Roentgenol 1988;151:295–299
Buetow PC, Buck JL, Ros PR, et al. Malignant vascular tumors of the liver: radiologic-pathologic correlation. Radiographics 1994;14:153–166
Caudana R, Morana G, Pirovano GP, et al. Focal Malignant hepatic lesions: MR imaging enhanced with gadolinium benzyloxypropionictetra-acetate (BOPTA)-preliminary results of phase II clinical application. Radiology 1996;199:513–520
Chen IY, Katz DS, Jeffrey RB, et al. Do arterial phase helical CT images improve detection or characterization of colorectal liver metastases? J Comput Assist Tomogr 1997;21(3):391–397
Chiao R, Mo L, Hall A, et al. B-mode blood flow imaging. AIUM Annual Convention, San Francisco, California, USA, April 2–5, 2000
Choi BI, Han JK, Hong SH, et al. Dysplastic nodules of the liver: imaging findings. Abdom Imaging 1999;24:250–257
Choi BI, Kim CW, Ham MC, et al. Sonographic characteristics of small hepatocellular carcinoma. Gastrointestinal Radiol 1989;14:255–261
Choi BI, Takayasu K, Han MC. Small hepatocellular carcinomas and associated nodular lesions of the liver: pathology, pathogenesis and imaging findings. AJR Am J Roentgenol 1993;160:1177–1187
Collier JD, Carpenter M, Burt AD, et al. Expression of mutant p53 protein in hepatocellular carcinoma. Gut 1994:35:98–100
Corrigan K, Semelka RC. Dynamic contrast-enhanced MR imaging of fibrolamellar hepatocellular carcinoma. Abdom Imaging 1995;20:122–125
Craig JR, Peters RL, Edmondson HA, et al. Fibrolamellar carcinoma of the liver: a tumor of adolescents and young adults with distinctive clincopathologic features. Cancer 1980;46:372–379
Fernandez MP, Redvanly RD. Primary hepatic malignant neoplasms. Radiol Clin North Am 1998;36:333–348
Enwonwu CO. The role of dietary aflatoxin in the genesis of hepatocellular cancer in developing countries. Lancet 1984;2:956–958
Enzinger FM, Weiss SW. Soft-tissue Tumors. Mosby Year-Book, St. Louis, 1983
Freeny PC, Baron RL, Teefey SA. Hepatocellular carcinoma: reduced frequency of typical findings with dynamic contrast-enhanced CT in a non-Asian population. Radiology 1992;182:143–148
Friedman AC, Lichtenstein JE, Goodman Z, et al. Fibrolamellar hepatocellular carcinoma. Radiology 1985;157:583–587
Fukayama M, Nihei Z, Takizawa T, et al. Malignant epithelioid hemangioendothelioma of the liver, spreading through the hepatic veins. Virchows Arch A Pathol Anat Histopathol 1984;404:275–287
Furui S, Itai Y, Ohtomo K, et al. Hepatic epithelioid hemangioendothelioma: report of five cases. Radiology 1989;171:63–68
Gabata T, Matsui O, Kadoya M, et al. Delayed MR imaging of the liver: correlation of delayed enhancement of hepatic tumors and pathologic appearance. Abdom Imaging 1998;23:309–313
Gates LK Jr, Cameron AJ, Nagorney DM, et al. Primary leiomyosarcoma of the liver mimicking liver abscess. Am J Gastroenterol 1995;90:649–652
Goodman ZD. Nonparenchymal and metastatic malignant tumors of the liver. In: Haubrich WS, Schaffner F, Berk JE (eds): Bockus Gastroenterology. Philadelphia: WB Saunders, 1995;2488–2500
Grazioli L, Morana G, Caudana R, et al. Hepatocellular carcinoma: correlation between gadobenate dimeglumine-enhanced MRI and pathologic findings. Invest Radiol 2000;35:25–34
Grazioli L, Olivetti L, Fugazzola C, et al. The pseudocapsule in hepatocellular carcinoma: correlation between dynamic MR imaging and pathology. Eur Radiol 1999;9:62–67
Hagspiel KD, Neidl KF, Eichenberger AC, et al. Detection of liver metastases: comparison of superparamagnetic iron oxide-enhanced and unenhanced MR imaging at 1.5 T with dynamic CT, intraoperative US and percutanous US. Radiology 1995;196:471–478
Hammerstingl R, Vogl TJ Schwarz W,. Contrast-enhanced MRI of focal liver lesions: differentiation and detection of primary and secondary liver lesions using Resovist-enhanced versus gadoliniumenhanced MRI in the same patient. Acad Radiol 1998;5(Suppl 1):75–79
Hardell L, Bengtsson NO, Jonsson U, et al. Aetiological aspects of primary liver cancer with special regard to alcohol, organic solvents and acute intermittent porphyria-an epidemiological investigation. Br J Cancer 1984;50:389–397
Harris KM, Schwartz ML, Slasky BS, et al. Posttransplantation cyclosporine-induced lymphoproliferative disorders: clinical and radiologic manifestations. Radiology 1987;162;697–700
Hayashi M, Matsui O, Ueda K, et al. Correlation between the blood supply and grade of malignancy of hepatocellular nodules associated with liver cirrhosis: evaluation by CT during intraarterial injection of contrast medium. AJR Am J Roentgenol 1999;172:969–976
Hollett MD, Jeffrey RB Jr, Nino-Murcia M, et al. Dual-phase helical CT of the liver: value of arterial phase scans in the detection of small (< or = 1.5 cm) malignant hepatic neoplasms. AJR Am J Roentgenol 1995;164:879–884
Ichikawa T, Federle MP, Grazioli L, et al. Fibrolamellar hepatocellular carcinoma: imaging and pathologic findings in 31 recent cases. Radiology 1999;213:352–361
Imai Y, Murakami T, Yoshida S, et al. Superpara-magnetic iron oxide-enhanced magnetic resonance images of hepatocellular carcinoma: correlation with histological grading. Hepatology 2000;32:205–212
Ishak KG, Sesterhenn IA, Goodman ZD, et al. Epithelioid hemangioendothelioma of the liver: a clinicopathologic and follow-up study of 32 cases. Hum Pathol 1984;15:839–852
Ishak KG. Malignant mesenchymal tumors of the liver. In: Okuda K, Ishak KG (eds): Neoplasms of the liver. Springer Verlag, New York, 1988,121–156
Ishak KG. Mesenchymal tumors of the liver. In Okuda K, Peter RL (eds): Hepatocellular Carcinoma. John Wiley & Sons, New York, 1976,228–587
Ishak KG. Pathogenesis of liver iseases. In: Farber E, Philips MJ, Kaufman N (eds): International Academy of Pathology Monograph, No. 28, Williams & Wilkins, Baltimore, 1987,314–315
Itai Y, Matsui O. Blood flow and liver imaging. Radiology 1997;202:306–314
Ito Y, Kojiro M, Nakshima T, et al. Pathomorphologic characteristics of 102 cases of thorotrast-related hepatocellular carcinoma, cholangiocarcinoma, and hepatic angiosarcoma. Cancer 1988;62:1153–1162
Jaffe ES. Malignant lymphomas: pathology of hepatic involvement. Semin Liver Dis 1987;7:257–268
Jang HJ, Lim HK, Lee WJ, et al. Ultrasonographic evaluation of focal hepatic lesions: comparison of pulse inversion harmonic, tissue harmonic, and conventional imaging techniques. J Ultrasound Med 2000;19:293–299
Kew MC. Hepatic tumors and cysts. In: Feldman M, Scharschmidt BF, Sleisenger MH (eds): Sleisenger and Fordtran’s Gastrointestinal and Liver Disease (6th ed). WB Saunders, Philadelphia, 1998,1364–1387
Kim AY, Choi BI, Kim TK, et al. Hepatocellular carcinoma: power Doppler US with a contrast agent — preliminary results. Radiology 1998;209:135–140
Kim T, Murakami T, Takahashi S, et al. Optimal phases of dynamic CT for detecting hepatocellular carcinoma: evaluation of unenhanced and triplephase images. Abdom Imaging 1999;24:473–480
Kojiro M, Nakashima T. Pathology of hepatocellular carcinoma. In: Okuda K, Ishak KG (eds): Neoplasms of the Liver. Springer-Verlag, New York, 1987,81–104
Kojiro M. Hepatocellular nodular lesions. In: Kojiro M (ed): Pathology of Early Hepatocellular Carcinoma and Related Lesions. Medical Publishers, Tokyo, 1996;148–165
Krinsky GA, Lee VS, Theise ND, et al. Hepatocellular carcinoma and dysplastic nodules in patients with cirrhosis: prospective diagnosis with MR imaging and explanation correlation. Radiology 2001;219:445–454
Kuszyk BS, Bluemke DA, Urban BA, et al. Portalphase contrast-enhanced helical CT for the detection of malignant hepatic tumors: sensitivity based on comparison with intraoperative and pathologic findings. AJR Am J Roentgenol 1996;166:91–95
LaBrecque DR. Neoplasia of the liver: focal nodular hyperplasia. In: Kaplowitz N (ed): Liver and Biliary Diseases (2nd ed): Williams & Wilkins, Baltimore, 1996, 391–438
Lai C, Gregory PB, Wu P, et al. Hepatocellular carcinoma in Chinese males and females: Possible causes for male predominance. Cancer 1987;60:1107–1110
Lauffer JM, Zimmermann A, Krahenbuhl L, et al. Epithelioid hemangioendothelioma of the liver. Cancer 1996:78(11):2318–2327
Lencioni R, Pinto F, Armillotta N, et al. Assessment of tumor vascularity in hepatocellular carcinoma: comparison of power Doppler US and color Doppler US. Radiology 1996;201:353–358
Lewis KH, Chezmar JL. Hepatic metastases. Magn Reson Imaging Clin N Am 1997;5:319–330
Lim JH, Cho JM, Kim EY, et al. Dysplastic nodules in liver cirrhosis: evaluation of hemodynamics with CT during arterial portography and CT hepatic arteriography. Radiology 2000;214:869–874
Lim JH, Choi D, Cho SK, et al. Conspicuity if hepatocellular nodular lesions in cirrhotic livers at ferumoxides-enhanced MR imaging: importance of Kupffer cell number. Radiology 2001;220:669–676
Locker GY, Doroshow JH, Zwelling LA, et al. The clinical features of hepatic angiosarcoma: a report of four cases and a review of the English literature. Medicine, (Baltimore) 1979;58:48–64
Manfredi R, Maresca G, Baron RL, et al. Delayed MR imaging of hepatocellular carcinoma enhanced by gadobenate dimeglumine (Gd-BOPTA). J Magn Reson Imaging 1999;9:704–710
Marti-Bonmati L, Ferrer D, Menor F, et al. Hepatic mesenchymal sarcoma: MRI findings. Abdom Imaging 1993;18:176–179
McLarney JK, Rucker PT, Bender GN et al. Fibrolamellar carcinoma of the liver: radiologic-pathologic correlation. Radiographics 1999;19:453–471
Miller WJ, Dodd GD 3rd, Federle MP, et al. Epithelioid hemangioendothelioma of the liver: imaging findings with pathologic correlation. AJR Am J Roentgenol 1992;159:53–57
Murakami T, Baron RL, Peterson MS, et al. Hepatocellular carcinoma: MR imaging with mangafodipir trisodium (Mn-DPDP). Radiology 1996;200:69–77
Murakami T, Kim T, Takamura M, et al. Hepatitis, cirrhosis and hepatoma. J Magn Reson Imaging 1998;8:346–358
Murakami T, Kim T, Takamura M, et al. Hypervascular hepatocellular carcinoma: detection with double arterial phase multi-detector row helical CT. Radiology 2001;218:763–767
Nakashima T, Kojiro M. Hepatocellular carcinoma: An Atlas of its Pathology. Springer-Verlag, Tokyo, 1987
Nerlich AG, Majewski S, Hunzelmann N, et al. Excessive collagen formation in fibrolamellar carcinoma of the liver: a morphological and biochemical study. Mod Pathol 1992;5:580–585
Noguchi S, Yamamoto R, Tatsuta M, et al. Cell features and patterns in fine-needle aspirates of hepatocellular carcinoma. Cancer 1986;58:321–328
Nzeako UC, Goodman ZD, Ishak KG. Hepatocellular carcinoma in cirrhotic and noncirrhotic livers: a clinico-histopathologic study of 804 North American patients. Am J Clin Pathol 1996;105:65–75
Ohsawa M, Aozasa K, Horiuchi K, et al. Malignant lymphoma of the liver. Report of five cases and review of the literature. Dig Dis Sci 1992;37:1105–1109
Oliver JH 3rd, Baron RL, Federle MP, et al. Detecting hepatocellular carcinoma: value of unenhanced or arterial phase CT imaging or both used in conjunction with conventional portal venous phase contrastenhanced CT imaging. AJR Am J Roentgenol 1996;167:71–77
Orsatti G, Hytiroglou P, Thung SN, et al. Lamellar fibrosis in the fibrolamellar variant of hepatocellular carcinoma: a role for transforming growth factor beta. Liver 1997;17:152–156
Parker SL, Tong T, Bolden S, et al. Cancer statistics. CA Cancer J Clin 1997;47:5–27
Paulson EK. Evaluation of the liver for metastatic disease. Semin Liver Dis 2001;21(2):225–236
Peterson MS, Baron RL, Marsh JW, et al. Pretransplantation surveillance for possible hepatocellular carcinoma in patients with cirrhosis: epidemiology and CT-based tumor detection rate in 430 cases with surgical pathologic correlation. Radiology; 2000;217:743–749
Peterson MS, Baron RL, Rankin SC, et al. Hepatic angiosarcoma: findings on multiphasic contrast-enhanced helical CT do not mimic hepatic hemangioma. AJR Am J Roentgenol 2000;175:165–170
Peterson MS, Murakami T, Baron RL. MR imaging patterns of gadolinium retention within liver neoplasms. Abdom Imaging 1998;23:592–599
Pinson CW, Lopez RR, Ivancev K, et al. Resection of primary hepatic malignant fibrous histiocytoma, fibrosarcoma and leiomyosarcoma. South Med 1994;87:384–391
Rizzi EB, Schinina V, Cristofaro M, et al. Nonhodgkin’s lymphoma of the liver in patients with AIDS: sonographic, CT and MRI findings. J Clin Ultrasound 2001;29:125–129
Rofsky NM, Earls JP. Mangafodipir trisodium injection (Mn-DPDP). A contrast agent for abdominal MR imaging. Magn Reson Imaging Clin N Am 1996;4:73–85
Ros PR, Murphy BJ, Buck JL, et al. Encapsulated hepatocellular carcinoma: radiologic findings and pathologic correlation. Gastrointest Radiol 1990;15:233–237
Ros PR, Taylor HM. Malignant Tumors of the liver. Textbook of gastrointestinal radiology, Vol II, second edition. Saunders, Philadelphia, 2000,1523–1568
Ros PR. Malignant liver tumors. In: Gore RM, Levine MS, Laufer I (eds): Gastrointestinal radiology. Saunders, Philadelphia, 1994,1897–1946
Runge VM, Lee C, Williams NM. Detectability of small liver metastases with gadolinium BOPTA. Invest Radiol 1997;32:557–565
Sakamoto M, Hirohashi S, Shimosato Y. Early stages of multistep hepatocarcinogenesis: adenomatous hyperplasia and early hepatocellular carcinoma. Hum Pathol 1991;22:172–178
Senéterre E, Taourel P, Bouvier Y, et al. Detection of hepatic metastases: ferumoxides-enhanced MR Imaging versus unenhanced MR Imaging and CT during arterial portography. Radiology 1996; 200:785–792
Sherlock S, Dooley J. Diseases of the liver and Biliary System (9th ed). Blackwell Scientific Publications, Oxford, 1993, 44–61
Shirkhoda A, Ros PR, Farah J, et al. Lymphoma of the solid abdominal viscera. Radiol Clin North Am 1990;28:785–799
Siskin GP, Haller JO, Miller S, et al. AIDS-related lymphoma: radiologic features in pediatric patients. Radiology 1995;196:63–66
Smalley SR, Moertel CG, Hilton JF, et al. Hepatoma in the noncirrhotic liver. Cancer 1988;62:1414–1424
Soyer P, Roche A, Levesque M, et al. CT of fibrolamellar hepatocellular carcinoma. J Computed Assist Tomogr 1991;15:533–538
Stevens WR, Johnson CD, Stephens DH, et al. Fibrolamellar hepatocellular carcinoma: stage at presentation and results of aggressive surgical management. AJR Am J Roentgenol 1995; 164:1153–1158
Sussman EB, Nydick I, Gray GF. Hemangioendothelial sarcoma of the liver and hemochromatosis. Arch Pathol 1974;97:39–42
Tamburro CH. Relationship of vinyl monomers and liver cancers: angiosarcoma and hepatocellular carcinoma. Semin Liver Dis 1984;4:158–169
Van Beers B, Roche A, Mathieu D, et al. Epithelioid hemangioendothelioma of the liver: MR and CT findings. J Comput Assist Tomogr 1992;16:420–424
Wang C, Ahlstrom H, Ekholm S, et al. Diagnostic efficacy of MnDPDP in MR imaging of the liver. A phase III multicentre study. Acta Radiol 1997;38:643–649
Weiss SW, Enzinger FM. Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma. Cancer 1982;50:970–981
Wernecke K, Peters PE, Kruger KG. Ultrasonographic patterns of focal hepatic and splenic lesions in Hodgkin’s and non-Hodgkin’s lymphoma. Br J Radiol 1987;60:655–660
Winston CB, Schwartz LH, Fong Y, et al. Hepatocellular carcinoma: MR imaging findings in cirrhotic livers and noncirrhotic livers. Radiology 1999;210:75–79
Worawattanakul S, Semelka RC, Kelekis NL, et al. Angiosarcoma of the liver: MR imaging pre-and post chemotherapy. Magn Reson Imaging 1997;15:613–617
Yamashita Y, Fan ZM, Yamamoto H, et al. Spinecho and dynamic gadolinium-enhanced FLASH MR imaging of hepatocellular carcinoma: correlation with histopathologic findings. J Magn Reson Imaging 1994;4:83–90
Yu JS, Kim KW, Kim EK, et al. Contrast enhancement of small hepatocellular carcinoma: usefulness of three successive early image acquisitions during multiphase dynamic MR imaging. AJR Am J Roentgenol 1999;173:597–604
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Schneider, G., Grazioli, L., Saini, S. (2006). Imaging of Malignant Focal Liver Lesions. In: Schneider, G., Grazioli, L., Saini, S. (eds) MRI of the Liver. Springer, Milano. https://doi.org/10.1007/88-470-0469-1_6
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