Advertisement

IBD: Cancer Risk and Surveillance

  • Gabriele Riegler
  • Ilaria Esposito

Keywords

Inflammatory Bowel Disease Ulcerative Colitis Adenomatous Polyposis Coli Primary Sclerosing Cholangitis Chronic Ulcerative Colitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Ekbom A, Helmick C, Zack M et al (1990) Increased risk of large bowel cancer in Crohn’s disease with colonic involvement. Lancet 336:357–359PubMedCrossRefGoogle Scholar
  2. 2.
    Langholz E, Munkholm P, Davidsen M et al (1992) Colorectal cancer risk and mortality in patients with ulcerative colitis. Gastroenterology 103:1444–1451PubMedGoogle Scholar
  3. 3.
    Choi PM, Zelig MP (1994) Similarity of colorectal cancer in CD and UC. Gut 35:950–954PubMedGoogle Scholar
  4. 4.
    Gyde S, Prior P, Dew MJ et al (1982) Mortality in ulcerative colitis. Gastroenterology 83:36–43PubMedGoogle Scholar
  5. 5.
    Munkholm P, Langholz E, Davidsen M, Binder V (1993) Intestinal cancer risk and mortality in patients with Crohn’s disease. Gastroenterology 105:1716–1723PubMedGoogle Scholar
  6. 6.
    Jess T, Winther KV, Munkholm P et al (2002) Mortality and causes of death in Crohn’s disease: follow-up of a population-based cohort in Copenhagen County, Denmark. Gastroenterology 122:1808–1814PubMedCrossRefGoogle Scholar
  7. 7.
    Eaden JA, Abrams KR, Mayberry JF (2001) The risk of colorectal cancer in ulcerative colitis: a meta analysis. Gut 48:526–535PubMedCrossRefGoogle Scholar
  8. 8.
    Ekbom A, Helmick C, Zack M, Ademi HO (1990) Ulcerative colitis and colorectal cancer. N Eng J Med 323:1228–1233CrossRefGoogle Scholar
  9. 9.
    Rutter M, Saunders B, Wilkinson K et al (2004) Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis. Gastroenterology 126:451–459PubMedCrossRefGoogle Scholar
  10. 10.
    Gyde SN, Prior P, Allan RN et al (1988) Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centers. Gut 29:206PubMedGoogle Scholar
  11. 11.
    Lennard-Jones JE (1985) Cancer risk in ulcerative colitis: surveillance or surgery. Br J Surg 72(Suppl):84Google Scholar
  12. 12.
    Collins RH, Feldman M, Fordtran JS (1987) Colon cancer, dysplasia and surveillance in patients with ulcerative colitis: a critical review. N Engl J Med 316:1654PubMedCrossRefGoogle Scholar
  13. 13.
    Levin B (1992) Inflammatory bowel disease and colon cancer. Cancer 70:1313PubMedCrossRefGoogle Scholar
  14. 14.
    Marchesa P, Lashner BA, Lavery IC et al (1997) The risk of cancer and dysplasia among ulcerative colitis patients with primary sclerosing cholangitis. Am J Gastroenterol 92:1285PubMedGoogle Scholar
  15. 15.
    Pinczowski D, Ekbom A, Baron J, et al (1994) Risk factors for colorectal cancer in patients with ulcertive colitis: a case-control study. Gastroenterology 107:117–120PubMedGoogle Scholar
  16. 16.
    Lashner BA, Provencher KS, Seidner DL et al (1997) The effect of folic acid supplementation on the risk for cancer or dysplasia in ulcerative colitis. Gastroenterology 112:29–32PubMedCrossRefGoogle Scholar
  17. 17.
    Lashner BA, Heindereich PA, Su GL et al (1989) Effect of folate supplementation on the incidence of dysplasia and cancer in chronic ulcerative colitis. Gastroenterology 97:255–259PubMedGoogle Scholar
  18. 18.
    Nuako KW, Ahlquist DA, Mahoney DW et al (1998) Familial predisposition for colorectal cancer in chronic ulcerative colitis: a case-control study. Gastroenterology 115:1079–1083PubMedCrossRefGoogle Scholar
  19. 19.
    Askling J, Dickman PW, Karlen P et al (2001) Colorectal cancer rates among first-degree relatives of patients with inflammatory bowel disease: a population-based study. Lancet 357:262–266PubMedCrossRefGoogle Scholar
  20. 20.
    Riegler G, Carratù R, Tartaglione MT et al (1988) Prevalence and relative risk of malignancy in relatives of inflammatory bowel disease patients an control subjects. J Clin Gastroenterol 27(3):211–214CrossRefGoogle Scholar
  21. 21.
    Riegler G, Caserta L, Castiglione F et al (2006) Increased risk of breast cancer in first-degree relatives of Crohn’s disease patients: an IG-IBD study. Dig Liv Dis 38(1):18–23CrossRefGoogle Scholar
  22. 22.
    Persson PG, Karlen P, Bernell O et al (1994) Crohn’s disease and cancer: a population-based cohort study. Gastroenterology 107:1675–1679PubMedGoogle Scholar
  23. 23.
    Fireman Z, Grossman A, Lilos P et al (1989) Intestinal cancer in patients with Cron’s disease: a population study in cental Israel. Scand J Gastroenterol 24:346–350PubMedGoogle Scholar
  24. 24.
    Jess T, Winther K, Munkholm P et al (2000) Is there an increased risk of intestinal and extra intestinal cancer in patients with Crohn’s disease? A population based cohort followed from 1962 to 1997. Gastroenterology 118(Suppl 2):1472Google Scholar
  25. 25.
    Gillen CD, Walmsley RS, Prior R et al (1994) Ulcerative colitis and Crohn’s disease: a comparison of the colorectal cancer risk in extensive colitis. Gut 35:651–5PubMedGoogle Scholar
  26. 26.
    Vogelstein B, Fearon ER, Hamilton SR et al (1988) Genetic alteration during colorectal tumour development. N Engl J Med 319:525PubMedCrossRefGoogle Scholar
  27. 27.
    Itzkowitz SH, Greenwald B, Meltzer SJ (1995) Colon carcinogenesis in inflammatory bowel disease. Inflamm Bowel Dis 1:142CrossRefGoogle Scholar
  28. 28.
    Burner GC, Rabinovitch PS, Haggit RC et al (1992) Neoplastic progression in ulcerative colitis: histology, DNA content, and loss of a p53 allele. Gastroenterology 103:1602Google Scholar
  29. 29.
    Riddell RH, Golman H, Ramsohoff DF et al (1983) Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical application. Hum Pathol 14:931–968PubMedCrossRefGoogle Scholar
  30. 30.
    Willenbucher RF (1996) Inflammatory bowel disease. Semin Gastrointest Dis 7:94–104PubMedGoogle Scholar
  31. 31.
    Lennard-Jones JE, Nelville DM, Morson BC et al (1990) Precancer and cancer in extensive ulcerative colitis: findings among 401 patients over 22 years. Gut 31:800–806PubMedGoogle Scholar
  32. 32.
    Goldman H (1996) Significance and detection of dysplasia in chronic colitis. Cancer 78:2261–2263PubMedCrossRefGoogle Scholar
  33. 33.
    Blackstone MO, Riddell RH, Roger BHG et al (1982) Dysplasia-associated lesion or mass (DALM) detected by colonscopy in long-standing ulcerative colitis: an indication for colectomy. Gastroenterology 80:366–374Google Scholar
  34. 34.
    Torres C, Antonioli D, Odze RD et al (1998) Polypoid dysplasia and adenomas in inflammatory bowel disease. Am J Surg Pathol 22:275–284PubMedCrossRefGoogle Scholar
  35. 35.
    Odze RD (1999) Adenomas and adenomas-like DALMs in chronic ulcerative colitis: a clinical, pathological and molecular review. Am J Gastroenterol 94:1746–1750PubMedCrossRefGoogle Scholar
  36. 36.
    Suzuki K, Muto T, Shinozaki M et al (1998) Differential diagnoses of dysplasia associated lesion or mass and coincidental adenoma in ulcerative colitis. Dis Colon Rectum 41:322PubMedCrossRefGoogle Scholar
  37. 37.
    Engelsgjerd M, Farraye FA, Odze RD (1999) Polypectomy may be adequate treatment for adenoma-like dysplastic lesions in chronic ulcerative colitis. Gastroenterology 117:1288PubMedCrossRefGoogle Scholar
  38. 38.
    Rubin PH, Friedman S, Harpaz N et al (1999) Colonoscopy polypectomy in chronic colitis: conservative management after endoscopic resection of dysplastic polyps. Gastroenterology 117:1295PubMedCrossRefGoogle Scholar
  39. 39.
    Morin PJ, Sparks AB, Korinek V et al (1997) Activation of B-catenin-Tcf signaling in colon cancer by mutations in B-catenin or APC. Science 275:1787PubMedCrossRefGoogle Scholar
  40. 40.
    Munemitsu S, Albert I, Souza B et al (1995) Regulation of intracellular beta-catenin levels by adenomatous polyposis coli (APC) tumour suppressor protein. Proc Natl Acad Sci USA 92:3046PubMedCrossRefGoogle Scholar
  41. 41.
    Vietri MT, Riegler G, Pappalardo D et al (2006) The Arg72Pro p53 polymorphism influences the clinical outcome of ulcerative colitis. Lab Invest (In press)Google Scholar
  42. 42.
    Ramsohoff DF, Riddell RH, Levin B (1985) Ulcerative colitis and colonic cancer: problems in assessing the diagnostic usefulness of mucosal dysplasia. Dis Colon Rectum 28:383CrossRefGoogle Scholar
  43. 43.
    Taylor BA, Pemberton JH, Carpenter HA et al (1992) Dysplasia in chronic ulcerative colitis: implications for colonoscopic surveillance. Dis Colon Rectum 35:950PubMedCrossRefGoogle Scholar
  44. 44.
    Warren R, Barwick KW (1983) Crohn’s colitis with adenocarcinoma and dysplasia: report of a case and review of 100 small and large bowel resection for Crohn’s disease to detect incidence of dysplasia. Am J Surg Pathol 7:151PubMedCrossRefGoogle Scholar
  45. 45.
    Provenzale D, Wong JB, Onken JE, Lipscomb J (1998) Performing a cost effectiveness analysis: surveillance of patients with ulcerative colitis. Am J Gastroenterol 93:872PubMedCrossRefGoogle Scholar
  46. 46.
    Fonkalsrud EW, Phillips JD (1990) Reconstruction of malfunctioning ileoanal pouch procedures as an alternative to permanent ileostomy. Am J Surg 160:245–251PubMedGoogle Scholar
  47. 47.
    Ruseler-Van Embden JGH, Schouten WR (1994) Pouchitis: result of microbial imbalance? Gut 35:658–664PubMedGoogle Scholar
  48. 48.
    Chaussade S, Denizot Y, Valleur P (1991) Presence of Paf-acether in stool of patients with pouch ileoanal anastomosis and pouchitis. Gastroenterology 100:1509–1514PubMedGoogle Scholar
  49. 49.
    Levin KE, Pemberton JH, Phillips SF (1992) Role of oxygen free radicals in the etiology of pouchitis. Dis Colon Rectum 35:452–456PubMedCrossRefGoogle Scholar
  50. 50.
    Kroesen AJ, John M, Schofelder G (1997) Expression of inducible nitric oxide syntase (iNOS) in pouchitis after ileoanal pouch surgery for ulcerative colitis. Langenbecks Archiv fur Chirurgie 114:451–454Google Scholar
  51. 51.
    Clausen MR, Tvede M, Mortensen PB (1992) Short-chain fatty acids in pouch contents from patients with and without pouchitis after ileal pouch-anal anastomosis. Gastroenterology 103:1144–1153PubMedGoogle Scholar
  52. 52.
    Penna C, Dozois RR, Tremaine W (1996) Pouchitis after ileal pouch anal anastomosis for chronic ulcerative colitis occur with increased frequency in patients with associated primary sclerosing cholangitis. Gut 38:234–239PubMedGoogle Scholar
  53. 53.
    Teixeira WGJ, Silva JH, Texeira MG (1999) Pouchitis: extracolonic manifestation of ulcerative colitis? Rev Hosp Clin Fac Med S Paulo 54:155–158PubMedGoogle Scholar
  54. 54.
    Moody GA, Javanthi V, Probert CS et al (1996) Long-term therapy with sulphasalazine protects against colorectal cancer in ulcerative colitis: a retrospective study of colorectal cancer risk and compliance with treatment in Leicestershire. Eur J Gastroenterol Hepatol 8:1179–1183PubMedGoogle Scholar
  55. 55.
    Eaden J, Abrams K, Ekbom A et al (2000) Colorectal cancer prevention in ulcerative colitis: a case-control study. Aliment Pharmacol Ther 14:145–153PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  • Gabriele Riegler
    • 1
  • Ilaria Esposito
    • 1
  1. 1.Unit of Gastroenterology and Digestive Endoscopy2nd University of NaplesNaplesItaly

Personalised recommendations