Dysplasia in Inflammatory Bowel Disease: from Genetics to Treatment

  • Emil Salmo
  • Patrick O’Connolly
  • Najib Haboubi


  • Definition of dysplasia is standard.

  • Classifications are clear.

  • Genetic studies are variable and may be useful in differentiating between lesions and helpful in choosing treatment modalities.

  • Treatment varies according to condition of lesion.

  • Not all CRC in IBD follow the logic of the lowgrade dysplasia, high-grade dysplasia then carcinoma sequence.

  • Modified chromoendoscopy is more sensitive than routine endoscopy in identifying dysplastic epithelium.


Inflammatory Bowel Disease Ulcerative Colitis Chronic Ulcerative Colitis Dysplastic Lesion Random Biopsy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  • Emil Salmo
    • 1
  • Patrick O’Connolly
    • 2
  • Najib Haboubi
    • 1
  1. 1.Department of Surgical PathologyTrafford Healthcare TrustManchesterUK
  2. 2.Department of Surgical Pathology and Gastrointestinal SurgeryHope HospitalManchesterUK

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