Abstract
The oxygenation of blood is impaired during anaesthesia, even in the patient with perfectly healthy lungs. Standard treatment of the patient includes a moderate increase in the oxygen supply, so that the oxygen concentration is around 30–40%. The mechanisms behind the impairment of gas exchange were poorly understood until the last 15 years and have since been mainly attributed to the collapse of lung tissue, i.e. atelectasis. In the following, the formation of atelectasis during anaesthesia and measures to prevent it or decrease its extent will be described.
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References
Damgaard Pedersen K, Qvist T (1980) Pediatric pulmonary CT-scanning. Anaesthesiainduced changes. Pediatr Radiol 9(3):145–148
Brismar B, Hedenstierna G, Lundquist H et al (1985) Pulmonary densities during anesthesia with muscular relaxation: a proposal of atelectasis. Anesthesiology 62(4):422–428
Lundquist H, Hedenstierna G, Strandberg Å et al (1995). CT-assessment of dependent lung densities in man during general anaesthesia. Acta Radiol 36:626–632
Hedenstierna G (2000) Anesthesia and gas exchange. In: Roca J, Rodriguez-Roisin R, Wagner PD (eds) Pulmonary and peripheral gas exchange in health and disease. Taylor & Francis, Oxford, pp 177–198
Strandberg A, Tokics L, Brismar B et al (1986) Atelectasis during anaesthesia and in the postoperative period. Acta Anaesthesiol Scand 30(2):154–158
Reber A, Engberg G, Sporre B et al (1996) Volumetric analysis of aeration in the lungs during general anaesthesia. Br J Anaesth 76(6):760–766
Hedenstierna G, Tokics L, Lundquist H et al (1994) Phrenic nerve stimulation during halothane anesthesia. Effects of atelectasis. Anesthesiology 80(4):751–760
Tokics L, Strandberg A, Brismar B et al (1987) Computerized tomography of the chest and gas exchange measurements during ketamine anaesthesia. Acta Anaesthesiol Scand 31(8):684–692
Rothen HU, Sporre B, Engberg G et al (1993) Re-expansion of atelectasis during general anaesthesia: a computed tomography study. Br J Anaesth 71(6):788–795
Rothen HU, Sporre B, Engberg G et al (1995) Influence of gas composition on recurrence of atelectasis after a reexpansion maneuver during general anesthesia. Anesthesiology 82(4):832–842
Rothen HU, Sporre B, Engberg G et al (1995) Prevention of atelectasis during general anaesthesia. Lancet 345:1387–1391
Hewlett AM, Hulands GH, Nunn JF et al (1974). Functional residual capacity during anaesthesia III: Artificial ventilation. Br J Anaesth 46(7):495–503
West JB, Dollery CT, Naimark A (1964) Distribution of blood flow in isolated lung: relations to vascular and alveolar pressure. J Appl Physiol 19:13–24
West JB (1977). State of the art: ventilation-perfusion relationships. AmRev Respir Dis 116(5):919–943
Nunn JF (1993) Applied respiratory physiology. Butterworths, Oxford, pp 43–44
Leith DE (1976) Barotrauma in human research. Crit Care Med 4(3):159–161
Dreyfuss D, Saumon G (1992). Barotrauma is volutrauma, but which volume is the one responsible? Intensive Care Med 18(3):139–141
Reber A, Engberg G, Wegenius G et al (1996) Lung aeration. The effect of preoxygenation and hyperoxygenation during total intravenous anaesthesia. Anaesthesia 51:733–737
Edmark L, Kostova-Aherdan K, Enlund M et al (2003) Optimal oxygen concentration during induction of general anesthesia. Anesthesiology 98:28–33
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Hedenstierna, G. (2006). Physiopathology of atelectasis during anaesthesia. In: Gullo, A. (eds) Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.. Springer, Milano. https://doi.org/10.1007/88-470-0407-1_30
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DOI: https://doi.org/10.1007/88-470-0407-1_30
Publisher Name: Springer, Milano
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