Skip to main content

Cerebrovascular Disease in HIV-Infected Patients

  • Chapter

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   159.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Malouf R, Jacquette G, Dobkin J, Brust JCM (1990) Neurologic disease in human immunodeficiency virusinfected drug abusers. Arch Neurol 47:1002–1007

    PubMed  CAS  Google Scholar 

  2. Mréjen S, Moulignier A (2000) Atteintes neurologiques et infection par le VIH. Flammarion Médecine-Sciences, Paris

    Google Scholar 

  3. Moulignier A, Moulonguet A (2003) Complications neurologiques in VIH 2004. In: VIH 2004. Katalama C, Girard P-M, Pialoux G (eds) Doin, Reuil Malmaison, pp 95–123

    Google Scholar 

  4. Sacktor N (2002) The epidemiology of human immunodeficiency virus-associated neurological disease in the era of highly active antiretroviral therapy. J Neurovirol 8[Suppl 2]:115–121

    PubMed  CAS  Google Scholar 

  5. Gray F, Chrétien F, Vallat-Decouvelaere AV, F Scaravilli (2003) The changing pattern in HIV neuropathology in the HAART era. J Neuropathol Exp Neurol 62:429–440

    PubMed  Google Scholar 

  6. Jellinger KA, Setinek U, Drlicek M, Böhm G, Steurer A, Lintner F (2000) Neuropathology and general autopsy findings in AIDS during the last 15 years. Acta Neuropathol 100:213–220

    Article  PubMed  CAS  Google Scholar 

  7. Snider WD, Simpson DM, Nielsen S, Gold JWM, Metroka CE, Posner JB (1983) Neurological complications of acquired immune deficiency syndrome: analysis of 50 patients. Ann Neurol 14:403–418

    Article  PubMed  CAS  Google Scholar 

  8. Rabinstein AA (2003) Stroke in HIV-infected patients: a clinical perspective. Cerebrovasc Dis 15:37–44

    Article  PubMed  Google Scholar 

  9. Pinto AN (1996) AIDS and cerebrovascular disease. Stroke 27:538–543

    PubMed  CAS  Google Scholar 

  10. Cole JW, Pinto AN, Hebel JR et al (2004) Acquired immunodeficiency syndrome and the risk of stroke. Stroke 35:51–56

    PubMed  Google Scholar 

  11. Levy RM, Bredesen DE (1988) Central nervous system dysfunction in acquired immunodeficiency syndrome. J Acquir Immune Defic Syndr 1:41–64

    PubMed  CAS  Google Scholar 

  12. Evers S, Nabavi D, Rahmann A, Heese C, Reichelt D, Husstedt W (2003) Ischaemic cerebrovascular events in HIV Infection. A cohort study. Cerebrovasc Dis 15:199–205

    Article  PubMed  Google Scholar 

  13. Hoffmann M, Berger JR, Nath A, Rayens (2000) Cerebrovascular disease in young, HIV-infected black Africans in the KwaZulu natal province of South Africa. J Neurovirol 6:229–236

    Article  PubMed  CAS  Google Scholar 

  14. d’Arminio A, Sabin CA, Phillips AN et al (2004) Writing Committee of the DAD Study Group. Cardio-and cerebrovascular events in HIV-infected persons. AIDS 18:1811–1817

    PubMed  CAS  Google Scholar 

  15. Bozzette SA, Ake CF, Tam HK, Chang SW, Louis TA (2003) Cardiovascular and cerebrovascular events in patients treated for human immunodeficiency virus infection. N Engl J Med 348:702–710

    PubMed  CAS  Google Scholar 

  16. Holmberg SD, Moorman AC, Williamson JM et al (2002) Protease inhibitors and cardiovascular outcomes in patients with HIV-1. Lancet 306:1747–1748

    Google Scholar 

  17. Levy RM, Bredesen DE, Rosenblum ML (1985) Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature. J Neurosurg 62:475–495

    PubMed  CAS  Google Scholar 

  18. Koppel BS, Wormser GP, Tuchman AJ, Maayan S, Hewlett D Jr, Daras M (1985) Central nervous system involvement in patients with acquired immunodeficiency syndrome (AIDS). Acta Neurol Scand 71:337–353

    PubMed  CAS  Google Scholar 

  19. Berger JR, Moskowitz L, Fischl M, Kelley RE (1987) Neurological disease as the presenting manifestation of acquired immunodeficiency syndrome. South Med J 80:683–686

    PubMed  CAS  Google Scholar 

  20. McArthur JC (1987) Neurological manifestations of AIDS. Medicine 66:407–437

    PubMed  CAS  Google Scholar 

  21. Engstrom JW, Lowenstein DH, Bredesen DE (1989) Cerebral infarctions and transient neurologic deficits associated with acquired immunodeficiency syndrome. Am J Med 86:528–532

    Article  PubMed  CAS  Google Scholar 

  22. Moskowitz LB, Hensley GT, Chan JC, Gregorios J, Conley FK (1984) The neuropathology of acquired immunodeficiency syndrome. Arch Pathol Lab Med 108:867–872

    PubMed  CAS  Google Scholar 

  23. Anders KH, Guerra WF, Tomiyasu U, Vinters HV (1986) The neuropathology of AIDS: UCLA experience and review. Am J Pathol 124:537–558

    PubMed  CAS  Google Scholar 

  24. Rosemberg S, Lopes MBS, Tsanadis AM (1986) Neuropathology of acquired immunodeficiency syndrome: analysis of 22 Brazilian cases. J Neurol Sci 76:187–198

    Article  PubMed  CAS  Google Scholar 

  25. Mizusawa H, Hirano A, Llena SF, Shintaku M (1988) Cerebrovascular lesions of AIDS. Acta Neuropathol 76:451–457

    PubMed  CAS  Google Scholar 

  26. Esiri MM, Scaravilli F, Millard PR, Harcourt-Webster JN (1989) Neuropathology of HIV infection in hemophiliacs: comparative necropsy study. Br Med J 299:1312–1315

    Article  CAS  Google Scholar 

  27. Berger JR, Harris JO, Gragorios J, Norenberg M (1990) Cerebrovascular disease in AIDS: a case control study. AIDS 4:239–244

    PubMed  CAS  Google Scholar 

  28. Kieburtz KD, Eskin TA, Ketonen L, Tuite MJ (1993) Opportunistic cerebral vasculopathy and stroke in patients with AIDS. Arch Neurol 50:430–432

    PubMed  CAS  Google Scholar 

  29. Connor MD, Lammie GA, Bell JE, Warlow CP, Simmonds P, Brettle RD (2000) Cerebral infarction in adult AIDS patients: observations from the Edinburgh HIV Autopsy Cohort. Stroke 31:2117–2126

    PubMed  CAS  Google Scholar 

  30. Gillams AR, Allen E, Hrieb K, Venna N, Craven D, Carter AP (1997) Cerebral infarction in patients with AIDS. Am J Neuroradiol 18:1581–1585

    PubMed  CAS  Google Scholar 

  31. Grindal AB, Cohen RJ, Saul RF et al (1978) Cerebral infarction in young adults. Stroke 9:39–42

    PubMed  CAS  Google Scholar 

  32. Kristensen B, Malm J, Carlberg B et al (1997) Epidemiology and etiology of ischemic stroke in young adults aged 18 to 44 years in northern Sweden. Stroke 28:1702–1709

    PubMed  CAS  Google Scholar 

  33. Berger K, Schulte H, Stögbauer F, Assmann G (1998) Incidence and risk factors for stroke in an occupational cohort: the PROCAM study. Stroke 29:1562–1566

    PubMed  CAS  Google Scholar 

  34. Qureshi AI, Janssen RS, Karon JM et al (1997) Human immunodeficiency virus infection and stroke in young patients. Arch Neurol 54:1150–1153

    PubMed  CAS  Google Scholar 

  35. Bajwa ZH, Libman R, Lipton RB et al (1991) Cerebrovascular disease in patients with HIV. Neurology 41[Suppl 1]:S295

    Google Scholar 

  36. Baily GG, Mandal BK (1995) Recurrent transient neurological deficits in advanced HIV infection. AIDS 9:709–712

    PubMed  CAS  Google Scholar 

  37. Brew BJ, Miller J (1996) Human immunodeficiency virus type 1-related transient neurological deficits. Am J Med 10:257–261

    Google Scholar 

  38. Rinaldi R, Manfredi R, Azzimondi G et al (1997) Recurrent ‘migrainelike’ episodes in patients with HIV disease. Headache 37:443–448

    Article  PubMed  CAS  Google Scholar 

  39. Klein JL, Price DA, Fisher M, Coker RJ (1996) Cytomegalovirus infection: a possible cause of recurrent transient neurological dysfunction in advanced HIV infection. AIDS 10:345–346

    PubMed  CAS  Google Scholar 

  40. Card T, Wathen CG, Luzzi GA (1998) Primary HIV-1 infection presenting with transient neurological deficit. J Neurol Neurosurg Psychiatry 6:281–282

    Google Scholar 

  41. Atalaia A, Ferro J, Antunes F (1992) Stroke in an HIVinfected patient J Neurol 239:356–357

    Article  PubMed  CAS  Google Scholar 

  42. Bradley TP, Vas G (1997) HIV type-1-related transient neurologic deficits. Am J Med 103:250

    PubMed  CAS  Google Scholar 

  43. Zunker P, Nabavi DG, Allardt A, Husstedt W, Schuierer G (1996) HIV-associated stroke: report of two unusual cases. Stroke 27:1694–1696

    PubMed  CAS  Google Scholar 

  44. Vittecoq D, Escaut L, Monsuez JJ (1998) Vascular complications associated with use of HIV protease inhibitors. Lancet 351:1959

    Article  PubMed  CAS  Google Scholar 

  45. Casado-Naranjo I, Toledo-Santos JA, Antolin-Rodriguez MA (1992) Ischemic stroke as the sole manifestation of HIV infection. Stroke 23:117–118

    PubMed  CAS  Google Scholar 

  46. Mochan A, Modi M, Modi G (2003) Stroke in black South African HIV-positive patients. A prospective analysis. Stroke 34:10–15

    Article  PubMed  Google Scholar 

  47. Roldan EO, Moskowitz L, Hensley GT (1987) Pathology of the heart in acquired immunodeficiency syndrome. Arch Pathol Lab Med 111:943–946

    PubMed  CAS  Google Scholar 

  48. Lai WW, Colan SD, Easley KA et al (2001) Dilation of the aortic root in children infected with human immunodeficiency virus type 1: The Prospective P2C2 HIV Multicenter Study. Am Heart J 141:661–670

    Article  PubMed  CAS  Google Scholar 

  49. Anders KH, Latta H, Chang BS, Tomiyasu U, Quddusi AS, Vinters HV (1989) Lymphomatoid granulomatosis and malignant lymphoma of the central nervous system in the acquired immunodeficiency syndrome. Hum Pathol 20:326–334

    Article  PubMed  CAS  Google Scholar 

  50. Geier SA, Perro C, Klauss V et al (1993) HIV-related ocular microangiopathic syndrome and cognitive functioning. J Acquir Immune Defic Syndr 6:252–258

    PubMed  CAS  Google Scholar 

  51. Scaravilli F, Daniel SE, Harcourt-Webster N, Guiloff RJ (1989) Chronic basal meningitis and vasculitis in acquired immunodeficiency syndrome. A possible role for human immunodeficiency virus. Arch Pathol Lab Med 113:192–195

    PubMed  CAS  Google Scholar 

  52. Yankner BA, Skolnik PR, Shoukimas GM, Gabuzda DH, Sobel RA, Ho DD (1986) Cerebral granulomatous angiitis associated with isolation of human Tlymphotropic virus type III from the central nervous system. Ann Neurol 20:362–364

    Article  PubMed  CAS  Google Scholar 

  53. Nogueras C, Sala M, Sasal M et al (2002) Recurrent stroke as a manifestation of primary angiitis of the central nervous system in a patient infected with human immunodeficiency virus. Arch Neurol 59:468–473

    Article  PubMed  Google Scholar 

  54. Evidente V, Yagnik P (1995) Stroke and stroke-like syndromes in the acquired immunodeficiency syndrome. Neurology 45[Suppl 4]:A444

    Google Scholar 

  55. Brannagan TH (1997) Retroviral-associated vasculitis of the nervous system. Neurol Clin 15:927–944

    PubMed  Google Scholar 

  56. van der Ven AJ, van Oostenbrugge RJ, Kubat B, Tervaert JW (2002) Cerebral vasculitis after initiation of antiretroviral therapy. AIDS 16:2362–2364

    PubMed  Google Scholar 

  57. Dehais C, Moulignier A, Deschamps R, Mikol J, Thiébaut J-B, Gout O (2004) Immune reconstitution vasculitis in an HIV-infected patient (abstract). Program of the Journées de Neurologie de Langue Française, Strasbourg 2004

    Google Scholar 

  58. Moulignier A, Laloum L, Chauveau E, Gout O, Rozenbaum W (2003) HIV-1-related ischaemic trochlear nerve palsy. J Neurol 250:108–109

    Article  PubMed  Google Scholar 

  59. Brilla R, Nabavi DG, Schulte-Atedorneburg G et al (1999) Cerebral vasculopathy in HIV infection revealed by transcranial Doppler: a pilot study. Stroke 30:811–813

    PubMed  CAS  Google Scholar 

  60. Tran Dinh YR, Mamo H, Cervoni J, Caulin C, Saimot AC (1990) Disturbances in the cerebral perfusion of human immune deficiency virus-1 seropositive asymptomatic subjects: a quantitative tomography study of 18 cases. J Nucl Med 31:1601–1607

    PubMed  CAS  Google Scholar 

  61. Rhew DC, Bernal M, Aguilar D, Lloeje U, Goetz MB (2003) Association between protease inhibitor use and increased cardiovascular risk in patients infected with human immunodeficiency virus: a systematic review. Clin Infect Dis 31:959–972

    Google Scholar 

  62. Maggi P, Serio G, Epifani G et al (2000) Premature lesions of the carotid vessels in HIV-1-infected patients treated with protease inhibitors. AIDS 14:123–128

    Google Scholar 

  63. Depayron M, Chessex S, Sudre P et al (2001) Premature atherosclerosis in HIV-infected individuals. Focus on protease inhibitor therapy. AIDS 15:329–334

    Google Scholar 

  64. Hollander M, Hak AE, Koudstaal PJ et al (2003) Comparison between measures of atherosclerosis and risk of stroke: the Rotterdam Study. Stroke 34:2367–2372

    Article  PubMed  CAS  Google Scholar 

  65. Brey RL, Chapman J, Levine SR et al (2003) Stroke and the antiphospholipid syndrome: consensus meeting, Taormina 2002. Lupus 12:508–513

    Article  PubMed  CAS  Google Scholar 

  66. Hassell KL, Kressin DC, Neumann A, Ellison R, Marlar RA (1994) Correlation of antiphospholipid antibodies and protein S deficiency with thrombosis in HIV-infected men. Blood Coagul Fibrinolysis 5:455–462

    PubMed  CAS  Google Scholar 

  67. Martin CM, Matlow AG, Chew E, Sutton D, Pruzanski W (1989) Hyperviscosity syndrome in a patient with acquired immunodeficiency syndrome. Arch Intern Med 149:1435–1436

    Article  PubMed  CAS  Google Scholar 

  68. Bruno A (2003) Cerebrovascular complications of alcohol and sympathomimetic drug abuse. Curr Neurol Neurosci Rep 3:40–45

    PubMed  Google Scholar 

  69. Hanyu S, Ikeguchi K, Imai H, Imai N, Yoshida M (1995) Cerebral infarction associated with 3,4-methylenedioxymethamphetamine (’ecstasy’) abuse. Eur Neurol 35:173

    PubMed  CAS  Google Scholar 

  70. Strobel M, Lamaury I, Brouzes F et al (1995) Accidents vasculaires cérébraux et sida. Rev Med Interne 16:743–746

    PubMed  CAS  Google Scholar 

  71. Moulignier A, Baudrimont M, Martin-Negrier ML, Mikol J, Lapresle C, Dupont B (1996) Fatal brain stem encephalitis due to herpes simplex virus type 1 in AIDS. J Neurol 243:491–493

    Article  PubMed  CAS  Google Scholar 

  72. Brust JC (2002) Neurologic complications of substance abuse. J Acquir Immune Defic Syndr 31[Suppl 2]:S29–S34

    PubMed  CAS  Google Scholar 

  73. Nolte KB, Brass LM, Fletterick CF (1996) Intracranial hemorrhage associated with cocaine abuse: a prospective autopsy study. Neurology 46:1291–1296

    PubMed  CAS  Google Scholar 

  74. Buttner A, Mall G, Penning R, Sachs H, Weis S (2003) The neuropathology of cocaine abuse. Leg Med 5[Suppl 1]:S240–242

    CAS  Google Scholar 

  75. Cohen JE, Eger K, Montero A, Israel Z (1998) Rapid spontaneous resolution of acute subdural hematoma and HIV related cerebral atrophy: case report. Surg Neurol 50:241–244

    PubMed  CAS  Google Scholar 

  76. Jordan BD, Navia BA, Petito C, Cho ES, Price RW (1985) Neurological syndromes complicating AIDS. Front Radiat Ther Oncol 19:82–87

    PubMed  CAS  Google Scholar 

  77. Meyohas MC, Roullet E, Rouzioux C et al (1989) Cerebral venous thrombosis and dual primary infection with human immunodeficiency virus and cytomegalovirus. J Neurol Neurosurg Psychiatry 52:1010–1011

    Article  PubMed  CAS  Google Scholar 

  78. Doberson MJ, Kleinschmidt-DeMasters BK (1994) Superior sagittal sinus thrombosis in a patient with acquired immunodeficiency syndrome. Arch Pathol Lab Med 118:844–846

    PubMed  CAS  Google Scholar 

  79. Iranzo A, Domingo P, Cadafalch J, Sambeat MA (1998) Intracranial venous and dural sinus thrombosis due to protein S deficiency in a patient with AIDS. J Neurol Neurosurg Psychiatry 64:688

    PubMed  CAS  Google Scholar 

  80. Berger JR, Harris JO, Gregorios J, Norenberg M (1990) Cerebrovascular disease in AIDS: a case control study. AIDS 4:239–244

    PubMed  CAS  Google Scholar 

  81. Afsari K, Frank J, Vaksman Y, Nguyen TV (2003) Intracranial venous sinus thrombosis complicating AIDS-associated nephropathy. AIDS Read 13:143–148

    PubMed  Google Scholar 

  82. Spiegel M, Schmidauer C, Kampfl A, Sarcletti M, Poewe W (2001) Cerebral ergotism under treatment with ergotamine and ritonavir. Neurology 57:743–744

    PubMed  CAS  Google Scholar 

  83. Martinez E, Collazos J, Mayo J (1998) Shock and cerebral infarct after rifampicin re-exposure in a patient infected with human immunodeficiency virus. Clin Infect Dis 27:1329–1330

    Article  PubMed  CAS  Google Scholar 

  84. Fénelon G, Gray F, Scaravilli F et al (1991) Ischemic myelopathy secondary to disseminated intravascular coagulation in AIDS. J Neurol 238:51–54

    PubMed  Google Scholar 

  85. Gray F, Belec L, Lescs MC (1994) Varicella-zoster virus infection of the central nervous system in the acquired immune deficiency syndrome. Brain 117:987–999

    PubMed  Google Scholar 

  86. Kenyon LC, Dulaney E, Montone KT, Goldberg HI, Liu GT, Lavi R (1996) Varicella-zoster ventriculoencephalitis and spinal cord infarction in a patient with AIDS. Acta Neuropathol 92:202–205

    Article  PubMed  CAS  Google Scholar 

  87. Park YD, Belman AL, Kim TS et al (1990) Stroke in pediatric acquired immunodeficiency syndrome. Ann Neurol 28:303–311

    Article  PubMed  CAS  Google Scholar 

  88. Patsalides AD, Wood LV, Atac GK, Sandifer E, Butman JA, Patronas NJ (2002) Cerebrovascular disease in HIV-infected pediatric patients: neuroimaging findings. Am J Roentgenol 179:999–1003

    Google Scholar 

  89. Visudtibhan A, Visudhiphan P, Chiemchanya S (1999) Stroke and seizures as the presenting signs of pediatric HIV infection. Pediatr Neurol 20:53–56

    Article  PubMed  CAS  Google Scholar 

  90. Husson RN, Saini R, Lewis LL, Butler KM, Patronas N, Pizzo PA (1992) Cerebral artery aneurysms in children infected with human immunodeficiency virus. J Pediatr 121:927–930

    PubMed  CAS  Google Scholar 

  91. Kure K, Llena JF, Lyman WD et al (1991) Human immunodeficiency virus-1 infection of the nervous system: an autopsy study of 268 adult, pediatric, and fetal brains. Hum Pathol 22:700–710

    Article  PubMed  CAS  Google Scholar 

  92. Lang C, Jacobi G, Kreuz W et al (1992) Rapid development of giant aneurysm at the base of the brain in an 8-year-old boy with perinatal HIV infection. Acta Histochem Suppl 42:83–90

    PubMed  CAS  Google Scholar 

  93. Bonnet D, Aggoun Y, Szezepanski I, Bellal N, Blanche S (2004) Arterial stiffness and endothelial dysfunction in HIV-infected children. AIDS 18:1037–1041

    PubMed  Google Scholar 

  94. Mazzoni P, Chiriboga CA, Millar WS, Rogers A (2000) Intracerebral aneurysms in human immunodeficiency virus infection: case report and literature review. Pediatr Neurol 23:252–255

    Article  PubMed  CAS  Google Scholar 

  95. Vilaseca MA, Sierra C, Colome C et al (2001) Hyperhomocysteinaemia and folate deficiency in human immunodeficiency virus-infected children. Eur J Clin Invest 31:992–998

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Italia

About this chapter

Cite this chapter

Moulignier, A. (2005). Cerebrovascular Disease in HIV-Infected Patients. In: Barbaro, G., Boccara, F. (eds) Cardiovascular Disease in AIDS. Springer, Milano. https://doi.org/10.1007/88-470-0358-X_7

Download citation

  • DOI: https://doi.org/10.1007/88-470-0358-X_7

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0309-5

  • Online ISBN: 978-88-470-0358-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics