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References
Runge VM, Knopp MV (1999) Off-label use and reimbursement of contrast media in MR. JMRI 10:489–495
Knopp MV, Lodemann KP, Kage U et al (2001) Administration of MR contrast agents outside of approved indications (off-label use). Radiologe 41:296–302
Knopp MV, von Tengg-Kobligk H, Floemer F et al (1999) Contrast agents for MRA: future directions. JMRI 10:314–316
de Haën C, Cabrini M, Akhnana L et al (1999) Gadobenate dimeglumine 0.5M solution for injection (MultiHance“): pharmaceutical formulation and physicochemical properties of a new magnetic resonance imaging contrast medium. J Comput Assist Tomogr 23(Suppl. 1):S161–S168
Grossman RI, Rubin DL, Hunter G et al (2000) Magnetic resonance imaging in patients with central nervous system pathology. A comparison of Opti-MARK (Gd-DTPA-BMEA) and Magnevist (Gd-DTPA). Invest Radiol 35:412–419
Benner T, Reimer P, Erb G et al (2000) Cerebral MR perfusion imaging: first clinical application of a 1M gadolinium chelate (gadovist 1.0) in a double-blinded randomized dose-finding study. J Magn Reson Imaging 12:371–380
Tombach B, Bremer C, Reimer P et al (2001) Renal tolerance of a neutral gadolinium chelate (gadobutrol) in patients with chronic renal failure: results of a randomized study. Radiology 218:651–657
Prince MR, Erel HE, Lent RW et al (2003) Gadodiamide administration causes spurious hypocalcemia. Radiology 227:630–646
Doorenbos CJ, Ozyilmaz A, van Wijnen M (2003) Severe pseudohypocalcemia after gadolinium-enhanced magnetic resonance angiography. N Engl J Med. 349:817–818
Kang HP, Scott MG, Joe BN et al (2004) Model for Predicting the Impact of Gadolinium on Plasma Calcium Measured by the o-Cresolphthalein Method. Clin Chem. 50:141–146
Normann PT, Froysa A, Svaland M (1995) Interference of gadodiamide injection (OMNISCAN) on the colorimetric determination of serum calcium, Scand J. Clin Lab Invest; 55:421–426
Lin J, Idee JM, Port M et al (1999) Interference of magnetic resonance imaging contrast agents with the serum calcium measurement technique using colorimetric reagents. J Pharm Biomed Anal. 21:931–43
Goyan M, Ruehm SG, Debatin JF (2000) MR Angiography: the role of contrast agents. Eur J Radiol 34:247–256
Hany TF, Schmidt M, Hilfiker PR, et al (1998) Optimization of contrast dosage for gadolinium-enhanced 3D MRA of the pulmonary and renal arteries. Magn Reson Imaging 16:901–906
Dong Q, Schoenberg SO, Carlos RC et al (1999) Diagnosis of renal vascular disease with MR angiography. Radiographics 19:1535–1554
Leung DA, Hagspiel KD, Angle JF et al (2002) MR angiography of the renal arteries. Radiol Clin North Am 40:847–865
Gibby WA, Gibby KA, Gibby WA (2004) Comparison of Gd DTPA-BMA (Omniscan) versus Gd HPDO3A (ProHance) retention in human bone tissue by Inductively Coupled Plasma Atomic Emission Spectroscopy. Invest Radiol 39:138–142
Tweedle M (1992) Physicochemical properties of gadoteridol and other magnetic resonance contrast agents. Invest Radiol 27(Suppl 1):2–6
Leung DA, Hagspiel KD, Angle JF et al (2002) MR angiography of the renal arteries. Radiol Clin North Am 40:847–865
Balzer JO, Loewe C, Davis K et al (2003) Safety of contrast-enhanced MR angiography employing gadobutrol 1.0 M as contrast material. Eur Radiol 13:2067–2074
Goyen M, Herborn CU, Vogt FM, et al (2003) Using a 1 M Gd-chelate (gadobutrol) for total-body three-dimensional MR angiography: preliminary experience. J Magn Reson Imaging 17:565–571
Goyen M, Lauenstein T, Herborn C et al (2001) 0.5 M Gd chelate (Magnevist) versus 1.0 M Gd chelate (Gadovist): dose-independent effect on image quality of pelvic three-dimensional MR-angiography. J Magn Reson Imaging 14:602–607
Herborn C, Lauenstein T, Ruehm S et al (2003) Intraindividual comparison of gadopentetate dimeglumine, gadobenate dimeglumine and gadobutrol for pelvic 3D magnetic resonance angiography. Invest Radiol 38:27–33
Hentsch A, Aschauer MA, Balzer JO, et al (2003) Gadobutrol-enhanced moving-table magnetic resonance angiography in patients with peripheral vascular disease: a prospective, multi-centre blinded comparison with digital subtraction angiography. Eur Radiol 13:2103–2114
Herborn CU, Ajaj W, Goyen M et al (2004) Peripheral vasculature: whole-body MR angiography with midfemoral venous compression-initial experience. Radiology 230:872–878
Fink C, Bock M, Kiessling F et al (2004) Time-resolved contrast-enhanced three-dimensional pulmonary MR-angiography: 1.0 M gadobutrol vs. 0.5 M gadopentetate dimeglumine. J Magn Reson Imaging 19:202–208
von Tengg-Kobligk H, Floemer F, Knopp MV (2003) [Multiphasic MR angiography as an intra-individual comparison between the contrast agents Gd-DTPA, Gd-BOPTA, and Gd-BT-DO3A] Radiologe 43:171–178. In German
Cavagna F, Maggioni F, Castelli P et al (1997) Gadolinium chelates with weak binding to serum proteins. A new class of high-efficiency, general purpose contrast agents for magnetic resonance imaging. Invest Radiol 32:780–796
Knopp M, Schoenberg S, Rehm C et al (2002) Assessment of Gadobenate Dimeglumine (Gd-BOPTA) for MR Angiography: Phase I Studies. Invest Radiol 37:706–715
Völk M, Strotzer M, Lenhart M et al (2001) Renal time-resolved MR angiography: quantitative comparison of gadobenate dimeglumine and gadopentetate dimeglumine with different doses. Radiology 220:484–488
Wikström J, Wasser MN, Pattynama PM, et al (2003) Gadobenate dimeglumine-enhanced magnetic resonance angiography of the pelvic arteries. Invest Radiol 38:504–515
Kroencke TJ, Wasser MN, Pattynama PM et al (2002) Gadobenate dimeglumine-enhanced MR angiography of the abdominal aorta and renal arteries. AJR Am J Roentgenol 179:1573–158
Prokop M, Schneider G, Vanzulli A et al (2005) Contrast-enhanced MR angiography of the renal arteries: blinded multicenter crossover comparison gadobenate dimeglumine and gadopentetate dimeglumine. Radiology (in press)
Pediconi F, Fraioli F, Catalano C et al (2003) Gadobenate dimeglumine (Gd-DTPA) vs gadopentetate dimeglumine (Gd-BOPTA) for contrast-enhanced magnetic resonance angiography (MRA): improvement in intravascular signal intensity and contrast to noise ratio. Radiol Med 106:87–93
Anzalone N, Scomazzoni F, Castellano R et al (2005) Carotid artery stenosis: intra-individual correlations of unenhanced 3D-TOF-MR Angiography, contrast-enhanced MR Angiography, and digital subtraction angiography versus rotational angiography for detection and grading. Radiology (in press)
Knopp MV, Giesel FL, von Tengg-Kobligk H et al (2003) Contrast-enhanced MR Angiography of the Run-off Vasculature: Intraindividual comparison of gadobenate dimeglumine with gadopentetate dimeglumine. J Magn Reson Imaging 17:694–702
Wyttenbach R, Gianella S, Alerci M et al (2003) Prospective Blinded Evaluation of Gd-DOTA-versus Gd-BOPTA-enhanced Peripheral MR Angiography, as Compared with Digital Subtraction Angiography. Radiology 227:261–269
Herborn CU, Goyen M, Lauenstein TC, et al (2003) Comprehensive time-resolved MRI of peripheral vascular malformations Am J Roentgenol 181:729–735
Winterer JT, Scheffler K, Paul G et al (2000) Optimization of contrast-enhanced MR angiography of the hands with a timing bolus and elliptically reordered 3D pulse sequence J Comput Assisted Tomogr 24:903–908
Ruehm SG, Goyen M, Barkhausen J et al (2001) Rapid magnetic resonance angiography for detection of atherosclerosis. Lancet 357:1086–1091
Goyen M, Herborn CU, Lauenstein TC et al (2002) Optimization of contrast dosage for gadobenate dimeglumine-enhanced high-resolution whole-body 3D magnetic resonance angiography Invest Radiol 37:263–268
Goyen M, Quick HH, Debatin JF et al (2002) Whole-body three-dimensional MR angiography with a rolling table platform: initial clinical experience. Radiology 224:270–277
Goyen M, Herborn CU, Kröger K et al (2003) Detection of atherosclerosis: systemic imaging for systemic disease with whole-body three-dimensional MR angiography — initial experience. Radiology 227:277–282
Kirchin MA, Pirovano G, Venetianer C et al (2001) Safety assessment of gadobenate dimeglumine (Multihance,): extended clinical experience from phase I studies to post-marketing surveillance. J Magn Reson Imaging 14:281–294
Huppertz A, Balzer T, Blakeborough A et al (2004) European EOB Study Group. Improved detection of focal liver lesions at MR imaging: multicenter comparison of gadoxetic acid-enhanced MR images with intraoperative findings. Radiology 230:266–275
Lauffer R, Parmelee D, Dunham S et al (1998) MS-325: albumin-targeted contrast agent for MR angiography. Radiology 207:529–538
Grist T, Korosec F, Peters D et al (1998) Steady-state and dynamic MR angiography with MS-325: initial experience in humans. Radiology 207:539–544
Perreault P, Edelman MA, Baum RA et al (2003) MR angiography with gadofosveset trisodium for peripheral vascular disease: phase II trial. Radiology 229:811–820
Caravan P, Cloutier NJ, Greenfield MT et al (2002) The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates. J Am Chem Soc. 124:3152–3162
Bluemke D, Stillman A, Bis K et al (2001) Carotid MR angiography: phase II study of safety and efficacy of MS-325. Radiology 219:114–122
Stuber M, Botnar RM, Danias PG et al (1999) Contrast agent-enhanced, free-breathing, three-dimensional coronary magnetic resonance angiography. J Magn Reson Imaging 10:790–799
Kraitchman DL, Chin BB, Heldman AW et al (2002) MRI detection of myocardial perfusion defects due to coronary artery stenosis with MS-325. J Magn Reson Imaging 15:149–158
Cavagna FM, Anelli PL, Lorusso V et al (2001) B-22956, a new intravascular contrast agent for MR coronary angiography. Proc of the Int. Soc. for Magnetic Resonance in Medicine, p 519 (Abstract)
La Noce A, Stoelben S, Scheffler K et al (2002) B22956/1, a new intravascular contrast agent for MRI: first administration to humans-preliminary results. Acad Radiol 9[Suppl]:S404–406
Cavagna FM, La Noce A, Maggioni F, et al (2002) MR Coronary Angiography with the New Intravascular Contrast Agent B-22956/1: First Human Experience. Proc of the Int. Soc. for Magnetic Resonance in Medicine, p 114 (Abstract)
Huber M, Paetsch I, Schnackenburg B, et al (2003) Performance of a new gadolinium-based intravascular contrast agent in free-breathing inversion-recovery 3D coronary MRA. Magn Reson Med 49:115–121
Paetsch I, Huber M, Bornstedt A et al(2004) Improved 3D free-breathing coronary MRA using gadocoletic acid (B-22956) for intravascular contrast enhancement. J Magn Reson Imaging 20:288–293
Gaillard S, Kubiak C, Stolz C et al (2002) Safety and pharmacokinetics of p792, a new blood-pool agent: results of clinical testing in nonpatient volunteers. Invest Radiol 37:161–166
Taupitz M, Schnorr J, Wagner S et al (2001) Coronary magnetic resonance angiography: experimental evaluation of the new rapid clearance blood pool contrast medium P792. Magn Reson Med 46:932–938
Dong Q, Hurst D, Weinmann H et al (1998) Magnetic resonance angiography with gadomer-17. An animal study original investigation. Invest Radiol 33:699–708
Herborn CU, Barkhausen J, Paetsch I et al (2003) Coronary arteries: contrast-enhanced MR imaging with SH L 643A-experience in 12 volunteers. Radiology 229:217–223
Port M, Corot C, Raynal I et al (2001) Physicochemical and biological evaluation of P792, a rapid-clearance blood-pool agent for magnetic resonance imaging. Invest Radiol 36:445–454
Reimer P, Bremer C, Allkemper T et al (2004) Myocardial perfusion and MR angiography of chest with SH U 555 C: results of placebo-controlled clinical phase I study. Radiology 231:474–481
Weishaupt D, Ruhm S, Binkert C et al (2000) Equilibrium-phase MR angiography of the aortoiliac and renal arteries using a blood pool contrast agent. Am J Roentgenol 175:189–195
Taylor A, Panting J, Keegan J et al (1999) Safety and preliminary findings with the intravascular contrast agent NC100150 injection for MR coronary angiography. J Magn Reson Imaging 9:220–227
Bachmann R, Conrad R, Kreft B et al (2002) Evaluation of a new ultrasmall superparamagnetic iron oxide contrast agent Clariscan, (NC100150) for MRI of renal perfusion: experimental study in an animal model. J Magn Reson Imaging 16:190–195
Reimer P, Allkemper T, Matuszewski L et al (1999) Contrast-enhanced 3D-MRA of the upper abdomen with a bolus-injectable SPIO (SH U 555 A). J Magn Reson Imaging 10:65–71
Mayo-Smith W, Saini S, Slater G et al (1996) MR contrast material for vascular enhancement: value of superparamagnetic iron oxide. Am J Roentgenol 166:73–77
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Knopp, M.V., Kirchin, M.A. (2005). Contrast Agents for MR Angiography: Current Status and Future Perspectives. In: Schneider, G., Prince, M.R., Meaney, J.F.M., Ho, V.B. (eds) Magnetic Resonance Angiography. Springer, Milano. https://doi.org/10.1007/88-470-0352-0_5
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