Skip to main content
SpringerLink
Log in

Pharmacology and selection of inotropic therapy

  • Conference paper
Book cover Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E.

  • 984 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Priebe HJ (2004) Vasoactive drugs. (IARS Review Course Lectures) Anesth Analg 64–70

    Google Scholar 

  2. Holubarsch C, Pieske B, Kretschmann B et al (1995) The functional role of angiotensin and endothelin in failing and nonfailing human myocardium. In: Dhalla NS, Beanish RE, Takeda N, Nagano M (eds) The failing heart. Lippincott-Raven, Philadelphia, pp 295–304

    Google Scholar 

  3. Holubarsch C, Ruf T, Goldstein DJ et al (1996) Existence of the Frank-Starling mechanism in the failing human heart: investigations on the organ, tissue, and sarcomere levels. Circulation 94:683–689

    PubMed  CAS  Google Scholar 

  4. Kass DA (1992) Clinical evaluation of left heart function by conductance catheter technique. Eur Heart J 13:E57–E64

    Google Scholar 

  5. Feldman MA (1993) Classification of positive inotropic agents. J Am Coll Cardiol 22:1223–1227

    Article  PubMed  CAS  Google Scholar 

  6. Lehtonen AL, Antilla S, Pentikäinen JP (2004) Pharmacokinetics and pharmacodynamicsm of intravenous inotropic agents. Clin Pharmacokinet 43:187–203

    Article  PubMed  CAS  Google Scholar 

  7. Haikala H, Nissinen E, Etemadzadeh E et al (1995) Troponin C mediated calcium sensitization induced by levosimendan does not impair relaxation. J Cardiovasc Pharmacol 25:794–801

    Article  PubMed  CAS  Google Scholar 

  8. Haikala H, Linden J (1995) Mechanisms of action of calcium-sensitizing drugs. J Cardiovasc Pharmacol 26(Suppl 1): S10–S19

    PubMed  CAS  Google Scholar 

  9. Lehonen LA (2001) Levosimendan: a parenteral calcium sensitising drug with additional vasodilatatory properties. Expert Opin Investig Drugs 10:955–970

    Article  Google Scholar 

  10. Krum H, Liew D (2003). New and emerging drug therapies for the management of acute heart failure. Intern Med J 33:515–520

    Article  PubMed  CAS  Google Scholar 

  11. Follath F, Cleland JG, Just H et al (2002) Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial. Lancet 360:196–202

    Article  PubMed  CAS  Google Scholar 

  12. Lochner A, Colesky F, Genade S (2000) Effect of a calcium-sensitizing agent, levosimendan, on the postcardioplegic inotropic response of the myocardium. Cardiovasc Drugs Ther 14:271–281

    Article  PubMed  CAS  Google Scholar 

  13. Greenberg BH (2002) Endothelin and endothelin receptor antagonists in heart failure. Congest Heart Fail 8:257–261

    PubMed  CAS  Google Scholar 

  14. Lee CR, Watkins ML, Patterson JH et al (2003) Vasopressin: a new target for the treatment of heart. Am Heart J 146:9–18

    Article  PubMed  CAS  Google Scholar 

  15. Schrier RW, Abraham W (1999) Hormones and hemodynamics in heart failure. N Engl J Med 341:577–585

    Article  PubMed  CAS  Google Scholar 

  16. Lindner KH, Strohmenger HU, Ensinger H et al (1992) Stress hormone response during and after cardiopulmonary resuscitation. Anesthesiology 77:662–668

    Article  PubMed  CAS  Google Scholar 

  17. Lindner KH, Haak T, Keller A et al (1996) Release of endogenous vasopressors during and after cardiopulmonary resuscitation. Heart 75:145–150

    PubMed  CAS  Google Scholar 

  18. Paradis NA, Rose MI, Garg U (1993) The effect of global ischemia and reperfusion on the plasma levels of vasoactive peptides: the neuroendocrine response to cardiac arrest and resuscitation. Resuscitation 26:261–269

    Article  PubMed  CAS  Google Scholar 

  19. Stiell IG, Hébert PC, Wells GA et al (2001) Vasopressin versus epinephrine for in hospital cardiac arrest: a randomised controlled trial. Lancet 358:105–109

    Article  PubMed  CAS  Google Scholar 

  20. Landry DW, Oliver JA (2001) The pathogenesis of vasodilatory shock. N Engl J Med 345:588–595

    Article  PubMed  CAS  Google Scholar 

  21. Landry DW, Levin HR, Gallant EM et al (1997) Vasopressin deficiency contributes to the vasodilation of septic shock. Circulation 95:1122–1125

    PubMed  CAS  Google Scholar 

  22. Patel BM, Chittock DR, Russell JA et al (2002) Beneficial effects of short-termvasopressin infusion during severe septic shock. Anesthesiology 96:576–582

    Article  PubMed  CAS  Google Scholar 

  23. Guzman JA, Rosado AE, Kruse JA (2003) Vasopressin vs. norepinephrine in endotoxic shock: systemic, renal, and splanchnic hemodynamic and oxygen transport effects. J Appl Physiol 95:803–809

    PubMed  CAS  Google Scholar 

  24. Feneck RO, Sherry KM, Withington PS et al (2001) Comparison of the hemodynamic effects of milrinone with dobutamine in patients after cardiac surgery. J Cardiothorac Vasc Anesth 15:306–315

    Article  PubMed  CAS  Google Scholar 

  25. Marik PE (2002) Low-dose dopamine: a systematic review. Intensive Care Med 28:877–883

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Anaesthesia and Critical Medicine, Heart Institute, Incor, Hospital das Clícascas, School of Medicine, SõPaulo University, SõPaulo, Brazil

    J. O. C. Auler (Director of Anaesthesia and Surgical ICU)

Authors
  1. J. O. C. Auler
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Perioperative Medicine, Intensive Care and Emergency, Trieste University School of Medicine, Trieste, Italy

    Antonino Gullo M.D. (Head) (Head)

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Italia

About this paper

Cite this paper

Auler, J.O.C. (2005). Pharmacology and selection of inotropic therapy. In: Gullo, A. (eds) Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E.. Springer, Milano. https://doi.org/10.1007/88-470-0351-2_41

Download citation

  • DOI: https://doi.org/10.1007/88-470-0351-2_41

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0288-3

  • Online ISBN: 978-88-470-0351-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation