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Musculoskeletal Diseases pp 54–61Cite as

Soft-Tissue Tumors and Tumor-Like Masses: A Systematic Approach to Diagnosis

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Summary

In summary, MR is the preferred modality for the evaluation of a soft-tissue mass following radiography. The radiologic appearance of certain soft-tissue tumors or tumorlike processes may be sufficiently unique to allow a strong presumptive radiologic diagnosis. It must be emphasized that MR imaging cannot reliably distinguish between benign and malignant lesions. When radiologic evaluation is nonspecific, one is ill advised to suggest that a lesion is benign or malignant solely on its MR appearance. When a specific diagnosis is not possible, knowledge of tumor prevalence by location and patient age, with appropriate clinical history and radiologic features, can be used to establish a suitably ordered differential diagnosis.

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References

  1. Hajdu SI (1981) Soft tissue sarcomas: classification and natural history. CA Cancer J Clin 31:271–280

    Article  PubMed  CAS  Google Scholar 

  2. du Boulay CEH (1985) Immunohistochemistry of soft tissue tumors: a review. J Pathol 146:77–94

    PubMed  Google Scholar 

  3. Weiss SW, Goldblum JR (2001) Enzinger and Weiss’s Soft Tissue Tumors, 4th ed. St. Louis: Mosby, pp 1–44

    Google Scholar 

  4. Mettlin C, Priore R, Rao U, Gamble D, Lane W, Murphy GP (1982) Results of the national soft-tissue sarcoma registry. Analysis of survival and prognostic factors. J Surg Oncology 19:224–227

    CAS  Google Scholar 

  5. Osment LS (1968) Cutaneous lipomas and lipomatosis. Surg Gynecol Obstet 127:129–132

    PubMed  CAS  Google Scholar 

  6. Leffert RD (1972) Lipomas of the upper extremity. J Bone Joint Surg Am 54-A:1262–1266

    Google Scholar 

  7. Rydholm A, Berg NO (1983) Size, site and clinical incidence of lipoma. Factors in the differential diagnosis of lipoma and sarcoma. Acta Orthop Scand 54:929–934

    PubMed  CAS  Google Scholar 

  8. Disler DG, Alexander AA, Mankin HJ, O’Connell JX, Rosenberg AE, Rosenthal DI (1993) Multicentric fibromatosis with metaphyseal dysplasia. Radiology 187:489–492

    PubMed  CAS  Google Scholar 

  9. Rock MG, Pritchard DJ, Reiman HM, Soule EH, Brewster RC (1984) Extra-abdominal desmoid tumors. J Bone Joint Surg Am 66-A:1369–1374

    Google Scholar 

  10. Sundaram M, Duffrin H, McGuire MH, Vas W (1988) Synchronous multicentric desmoid tumors (aggressive fibromatosis) of the extremities. Skeletal Radiol 17:16–19

    PubMed  CAS  Google Scholar 

  11. Moser RP, Parrish WM (2001) Radiologic evaluation of soft tissue tumors. In: Weiss SW, Goldblum JR. Enzinger and Weiss’s Soft Tissue Tumors, 4th ed. St. Louis: Mosby, pp 45–102

    Google Scholar 

  12. Rubin DA, Kneeland JB (1994) MR imaging of the musculoskeletal system: technical considerations for enhancing image quality and diagnostic yield. AJR 163:1155–1163

    PubMed  CAS  Google Scholar 

  13. Mirowitz SA (1993) Fast scanning and fat-supression MR imaging of musculoskeletal disorders. AJR 161: 1147–1157

    PubMed  CAS  Google Scholar 

  14. Shuman WP, Baron RL, Peters MJ, Tazioli PK (1989) Comparison of STIR and spin-echo MR imaging at 1.5T in 90 lesions of the chest, liver and pelvis. AJR 152:853–859

    PubMed  CAS  Google Scholar 

  15. Dwyer AJ, Frank JA, Sank VJ, Reinig JW, Hickey AM, Doppman JL (1988) Short-Ti inversion-recovery pulse sequence: analysis and initial experience in cancer imaging. Radiology 168:827–836

    PubMed  CAS  Google Scholar 

  16. Beltran J, Chandnani V, McGhee RA, Kursungoglu-Brahme S (1991) Gadopentetate dimeglumine-enhanced MR imaging of the musculoskeletal system. AJR 156:457–466

    PubMed  CAS  Google Scholar 

  17. Verstraete KL, De Deene Y, Roels H, Dierick A, Uyttendaele D, Kunnen M (1994) Benign and malignant musculoskeletal lesions: dynamic contrast-enhanced MR imaging-parametric “first pass” images depict tissue vascularization and perfusion. Radiology 192:835–843

    PubMed  CAS  Google Scholar 

  18. van Rijswijk CSP, Geirnaerdt MJA, Hogendoorn PCW, et al (2004) Soft tissue tumors: value of static and dynamic gadopentetate dimeglumine-enhanced MR imaging in prediction of malignancy. Radiology 233:493–502

    PubMed  Google Scholar 

  19. Harkens KL, Moore TE, Yuh WTC, et al (1993) Gadolinium-enhanced MRI of soft-tissue masses. Australas Radiol 37:30–34

    PubMed  CAS  Google Scholar 

  20. Seeger LL, Widoff BE, Bassett LW, Rosen G, Eckardt JJ (1991) Preoperative evaluation of osteosarcoma: value of gadopentitate dimeglumine-enhanced MR imaging. AJR 157:347–351

    PubMed  CAS  Google Scholar 

  21. Kransdorf MJ, Murphey MD (1997) The use of gadolinium in the MR evaluation of soft tissue tumors. Semin Ultrasound CT MR 18:251–268

    PubMed  CAS  Google Scholar 

  22. Kransdorf MJ, Jelinek JS, Moser, et al (1989)Soft-tissue masses: diagnosis using MR imaging. AJR 153: 541–547

    PubMed  CAS  Google Scholar 

  23. Berquist TH, Ehman RL, King BF, Hodgman CG, Ilstrup DM (1990) Value of MR imaging in differentiating benign from malignant soft tissue masses: study of 95 lesions. AJR 155:1251–1255

    PubMed  CAS  Google Scholar 

  24. Crim JR, Seeger LL, Yao L, Chandnani V, Eckardt JJ (1992) Diagnosis of soft-tissue masses with MR imaging: can benign masses be differentiated from malignant ones? Radiology 185:581–586

    PubMed  CAS  Google Scholar 

  25. Myhre-Jensen O (1981) A consecutive 7-year series of 1331 benign soft tissue tumors. Clinicopathologic data. Comparison with sarcomas. Acta Orthop Scand 52:287–293

    PubMed  CAS  Google Scholar 

  26. Rydholm A (1983) Management of patients with soft-tissue tumors. Strategy developed at a regional oncology center. Acta Orthop Scand Suppl 203:13–77

    PubMed  CAS  Google Scholar 

  27. Peabody TD, Simon MA (1993) Principles of staging of soft-tissue sarcomas. Clin Orthop 289:19–31

    PubMed  Google Scholar 

  28. Beltran J, Simon DC, Katz W, Weis LD (1987) Increased MR signal intensity in skeletal muscle adjacent to malignant tumors: pathologic correlation and clinical relevance. Radiology 162:251–255

    PubMed  CAS  Google Scholar 

  29. Hanna SL, Fletcher BD, Parham DM, Bugg MF (1991) Muscle edema in musculoskeletal tumors: MR imaging characteristics and clinical significance. J Magn Reson Imaging 1:441–449

    PubMed  CAS  Google Scholar 

  30. DeSchepper A, Ramon F, Degryse H (1992) Statistical analysis of MRI parameters predicting malignancy in 141 soft tissue masses. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr: 156:587–591

    CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Radiology, Mayo Clinic, Jacksonville, FL, USA

    M.J. Kransdorf

  2. Department of Radiologic Pathology, Armed Forces Institute of Pathology, Walter Reed Army Medical Center, Washington, DC, USA

    M.J. Kransdorf & M.D. Murphey

  3. Department of Radiology and Nuclear Medicine, Uniformed Services, University of the Heath Sciences, Bethesda, MD, USA

    M.D. Murphey

  4. Department of Radiology, University of Maryland School of Medicine, Baltimore, MD, USA

    M.D. Murphey

Authors
  1. M.J. Kransdorf
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  2. M.D. Murphey
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Editor information

Editors and Affiliations

  1. Department of Radiology, University Hospital Balgrist, Zurich, Switzerland

    J. Hodler

  2. Kantonsspital, Institut für Radiologie, Winterthur, Switzerland

    Ch. L. Zollikofer

  3. Universitätsspital Nuklearmedizin, Zurich, Switzerland

    G. K. von Schulthess

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© 2005 Springer-Verlag Italia

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Kransdorf, M., Murphey, M. (2005). Soft-Tissue Tumors and Tumor-Like Masses: A Systematic Approach to Diagnosis. In: Hodler, J., Zollikofer, C.L., von Schulthess, G.K. (eds) Musculoskeletal Diseases. Springer, Milano. https://doi.org/10.1007/88-470-0339-3_9

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  • DOI: https://doi.org/10.1007/88-470-0339-3_9

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0318-7

  • Online ISBN: 978-88-470-0339-2

  • eBook Packages: MedicineMedicine (R0)

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