Skip to main content
SpringerLink
Log in

Contrast Enhancement of the Growing Skeleton: Rationale and Optimization in Pediatric MRI

  • Chapter
Musculoskeletal Diseases

  • 1162 Accesses

Conclusions

Optimization of gadolinium-enhanced musculoskeletal MRI warrants special attention to the timing of data acquisition with respect to contrast administration as well as to selecting the appropriate sequences and postprocessing techniques for a given child, for a given anatomical region and for a given clinical problem. Recent advances in contrast-enhancement provide new information, both qualitative and quantitative, on the endochondral growth process and on the mechanisms of neovascularization and revascularization. All of these elements are important in dictating appropriate management.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Babyn PS, Kim HK, Gahunia HK, Lemaire C, Salter RB, Fornasier V, Pritzker KP (1998) MRI of the cartilaginous epiphysis of the femoral head in the piglet hip ischemic damage. J Magn Reson Imaging 8:717–723

    PubMed  CAS  Google Scholar 

  2. Babyn PS, Kim HK, Lemaire C, Gahunia HK, Cross A, DeNanassy J, Pritzker KP (1996) High-resolution magnetic resonance imaging of normal porcine cartilage epiphyseal maturation. J Magn Reson Imaging 6:172–179

    PubMed  CAS  Google Scholar 

  3. Babyn PS, Ranson M, Mc Carville ME (1998) Normal bone marrow: signal characteristics and fatty conversion. Magn Reson Imaging Clin N Am 6:473–495

    PubMed  CAS  Google Scholar 

  4. Barnewolt CE, Chung T (1998) Techniques, coils, pulse sequences and contrast enhancement in pediatric musculoskeletal MR imaging, Magn Reson Imaging Clin N Am 6:441–453

    PubMed  CAS  Google Scholar 

  5. Barnewolt CE, Shapiro F, Jaramillo D (1997) Normal Gadolinium-enhanced MR images of the developing appendicular skeleton: part I Cartilaginous epiphysis and physis. Am J Roentgenol 169:183–189

    CAS  Google Scholar 

  6. Dwek JR, Shapiro F, Laor T, Barnewolt CR, Jaramillo D (1997) Normal Gadolinium-enhanced MR images of the developing appendicular skeleton: Part 2. Epiphyseal and metaphyseal marrow. Am J Roentgenol 169:191–196

    CAS  Google Scholar 

  7. Erlemann R, Reiser MF, Peters PE et al (1989) Musculoskeletal neoplasms: static and dynamic Gd-DTPA-enhanced MR imaging. Radiology 171:767–773

    PubMed  CAS  Google Scholar 

  8. Herve-Somma CM, Sebag GH, Prieur AM, Bonnerot V, Lallemand DP (1992) Juvenile rheumatoid arthritis of the knee: MR evaluation with Gd-Dota. Radiology 182:93–98

    PubMed  CAS  Google Scholar 

  9. Jaramillo D, Shapiro F (1998) Musculoskeletal trauma in children. Magn Reson Imaging Clin N Am 6:521–536

    PubMed  CAS  Google Scholar 

  10. Jaramillo D, Shapiro F (1998) Growth cartilage: normal appearance, variants and abnormalities, Magn Reson Imaging Clin N Am 6:455–471

    PubMed  CAS  Google Scholar 

  11. Jaramillo D, Villegas-Medina O, Laor T, Shapiro F, Millis MB (1998) Gadolinium-enhanced MR imaging of pediatric patients after reduction dysplastic hips: assessment of femoral head position, factors impeding and femoral head ischemia, Am J Roentgenol. 170:1633–1637

    CAS  Google Scholar 

  12. Lamer S, Sebag GH (2000) MRI and ultrasound in children with juvenile chronic arthritis. Eur J Radiol 33:85–93

    Article  PubMed  CAS  Google Scholar 

  13. Lamer S, Dorgeret S, Khairouni S, Brillet PY, Bacheville E, Bloch J, Penneçot GF, Hassan M, Sebag G (2002) Femoral head vascularisation in Legg-Calvé-Perthes disease: comparison of dynamic gadolinium-enhanced subtraction MRI with bone scintigraphy. Pediatr Radiol 32:580–585

    Article  PubMed  Google Scholar 

  14. Polisson RP, Schoenberg OI, Fischman A et al (1995) Use of magnetic resonance imaging and positron emission tomography in the assessement of synovial volume and glucose metabolism in patients with rheumatoid arthritis. Arthritis Rheum 38:819

    PubMed  CAS  Google Scholar 

  15. Sebag GH, Pinzuti V, Argyropoulou M, Elmaleh M (1997) Doppler ultrasonography in the study of the vascularization of the femoral head in the newborns. J Radiol 78:289–292

    PubMed  CAS  Google Scholar 

  16. Sebag GH, Dubois J, Tabet M, Bonato A, Lallemand D (1993) Pediatric spinal bone marrow: assessment of normal age-related change MRI appearance. Pediatr Radiol 23:515–518

    Article  PubMed  CAS  Google Scholar 

  17. Sebag GH, Ducou le Pointe H, Klein I, Maiza D, Mazda K, Bensahel H, Hassan M (1997) Dynamic Gadolinium-enhanced subtraction MR imaging a simple technique in the early diagnosis of Legg-Calve-Perthes disease: preliminary results. Pediatr Radiol 27:216–220

    Article  PubMed  CAS  Google Scholar 

  18. Vanel D, Vertraete KL, Shapeero LG (1997). Primary tumors of the musculoskeletal system. Radiol Clin North Am 35:213–237

    PubMed  CAS  Google Scholar 

  19. Verstraete KL, Dierick A, De Deene Y et al (1994) Firstpass images of musculoskeletal lesions: a new and useful diagnostic application of dynamic contrast-enhanced MRI. Magn Reson Imaging 12:687–690

    PubMed  CAS  Google Scholar 

  20. Verstraete KL, Van der Woude HJ, Hogendoorn PR et al (1996) Dynamic contrast-enhanced MR imaging of musculoskeletal tumors: basic principles and clinical applications. J Magn Reson Imaging 6:311–321

    PubMed  CAS  Google Scholar 

  21. Sebag GH (1998) Disorders of the hip. Magn Imaging Clin N Am 6:627–631

    CAS  Google Scholar 

  22. Tsao AK, Dias LS, Conway JJ et al (1997). The prognostic value and significance of bone scintigraphy in LCP. J Pediatr Orthop 17:230–239

    PubMed  CAS  Google Scholar 

  23. Sebag GH, Laor T, Quignodon JF (2004) Imaging in children. In: Maddison PJ, Isenberg DA, Woo P, Glass DN (eds) Oxford textbook of rheumatology, third edition. Oxford University Press, New York, pp 534–52

    Google Scholar 

  24. Winalski CS, Aliabadi P, Wright JR et al (1993) Enhancement of joint fluid with intravenously administered gadopentetate demeglumine: technique, rationale and implications. Radiology 187:179

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pediatric Radiology, Faculté de Médecine Lariboisière-Saint-Louis, Université Paris VII - Hôpital R. Debré-Assistance Publique-Hôpitaux de Paris, Paris, France

    G. Sebag

Authors
  1. G. Sebag
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Radiology, University Hospital Balgrist, Zurich, Switzerland

    J. Hodler

  2. Kantonsspital, Institut für Radiologie, Winterthur, Switzerland

    Ch. L. Zollikofer

  3. Universitätsspital Nuklearmedizin, Zurich, Switzerland

    G. K. von Schulthess

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Italia

About this chapter

Cite this chapter

Sebag, G. (2005). Contrast Enhancement of the Growing Skeleton: Rationale and Optimization in Pediatric MRI. In: Hodler, J., Zollikofer, C.L., von Schulthess, G.K. (eds) Musculoskeletal Diseases. Springer, Milano. https://doi.org/10.1007/88-470-0339-3_25

Download citation

  • DOI: https://doi.org/10.1007/88-470-0339-3_25

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0318-7

  • Online ISBN: 978-88-470-0339-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation