Abstract
Traumatic brain injury is relatively common in military and law enforcement activities, despite ongoing improvements in head protection gear and in medical aid procedures and evacuation equipment in battlefield and conflict scenarios. In this chapter, we provide the relevant anatomical and physiological background which is relevant for understanding the occurrence and consequences of a traumatic brain injury and its subcategories. Next, we review the biomechanics of traumatic brain injury, and describe biomechanical injury criteria and thresholds. Finally, we introduce the concepts of modelling brain injuries by means of finite element techniques which consider the biomechanical properties of the head and neck tissues. The possible applications of such computational modelling and simulations, particularly for developing and testing military head-protection equipment, are discussed as well.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Notes
- 1.
Abbreviated Injury Scale (AIS) is a standard system for classifying injuries according to type and severity following vehicle accidents. AIS score is time-independent and is given to each body area and each injury independently. AIS reflects the injury itself, and does not account for its consequences or complications. AIS scores refer to the following injury severities: 0Â =Â non-injured, 1Â =Â minor, 2Â =Â moderate, 3Â =Â serious, 4Â =Â sever, 5Â =Â critical, 6Â =Â untreatable, [55].
References
Maas, A.I.R., Stocchetti, N., Bullock, R.: Moderate and severe traumatic brain injury in adults. Lancet Neurol 7, 728–741 (2008)
Brooks, A.J., Clasper, J., Midwinter, M.J., Hodgetts, T.J., Mahoney, P.F.: Ryan’s Ballistic Trauma—A Practical Guide, 3rd edn, Chaps. 5, 6, 10. Springer, Berlin (2011)
Owens, B.D., Kragh, J.F., Wenke, J.C., Macaitis, J., Wade, C.E., Holcomb, J.B.: Combat wounds in operation Iraqi Freedom and Operation Enduring Freedom. J. Trauma Inj. Infect. Crit. Care 64(2), 295–299 (2008)
Okie, S.: Traumatic brain injury in the war zone. New Engl. J. Med. 352(20), 2043–2047 (2005)
Wallace, D., Rayner, S.: Combat helmets and blast traumatic brain injury. J. Mil. Veterans’ Health 20(1), 10–17 (2012)
Lenhart, M.K., Savitsky, E., Eastridge, B.: Chapter 8—Traumatic brain injury. In: Combat Casualty Care—Lessons Learned from OEF and OIF, Office of the Surgeon General Department of the Army, United States of America (2012), pp. 347–362
Kobayashi, M., Mellen, P.F.: Rubber bullet injury—Case report with autopsy observation and literature review. Am. J. Forensic Med. Pathol. 30(3), 262–267 (2009)
Meyer, K.S., Marion, D.W., Coronel, H., Jaffee, M.S.: Combat-related traumatic brain injury and its implications to military healthcare. Psychiatr. Clin. North Am. 33(4), 783–796 (2010)
Warden, D.: Military TBI during the Iraq and Afghanistan wars. J. Head Trauma Rehab. 21(5), 398–402 (2006)
Rodriguez, C., Weisbrod, A.B., Bell, R., Neal, C., Armonda, R., Dorlac, W., Schreiber, M., Dunne, J.R.: Long-term outcomes of combat casualties sustaining penetrating traumatic brain injury. J. Trauma Acute Care Surg. 73(6), 1525–1530 (2012)
Langlois, J.A., Rutland-Brown, W., Thomas, K.E.: Traumatic brain injury in the United States; emergency department visits, hospitalizations, and deaths. National Center for Injury Prevention and Control (U.S.), Division of Injury and Disability Outcomes and Programs, Atlanta (2004)
Rothman, M.S., Arciniegas, D.B., Filley, C.M., Wierman, M.E.: The neuroendocrine effects of traumatic brain injury. J. Neuropsychiatry Clin. Neurosci. 19(4), 363–372 (2007)
Humphreys, I., Wood, R.L., Phillips, C.J., Macey, S.: The costs of traumatic brain injury: a literature review. Clinico Econ. Outcomes Res. 5(26), 281–287 (2013)
Jacobs, H.E.: The Los Angeles Head Injury Survey: procedures and initial findings. Arch. Phys. Med. Rehabil. 69(6), 425–431 (1988)
Fleminger, S., Oliver, D.L., Williams, W.H., Evans, J.: The neuropsychiatry of depression after brain injury. Neuropsychol. Rehab. Int. J. 13(1–2), 65–87 (2003)
Wood, R.L., Yurdakul, L.K.: Change in relationship status following traumatic brain injury. Brain Inj. 11(7), 491–501 (1997)
Saatman, K.E., Duhaime, A.C., Bullock, R., Maas, A.I., Valadka, A., Manley, G.T., Workshop Scientific Team and Advisory Panel Members: Classification of traumatic brain injury for targeted therapies. J. Neurotrauma 25(7), 719–738 (2008)
Department of Defence and Department of Veterans Affairs, Traumatic Brain Injury Task Force (2008). (Online) Available: http://www.cdc.gov/nchs/data/icd/Sep08TBI.pdf
Graham, D.I., Hume Adams, J., Nicoll, J.A.R., Maxwell, W.L., Gennarelli, T.A.: The nature, distribution and causes of traumatic brain injury. Brain Pathol. 5, 397–406 (1995)
Smith, D.H., Meaney, D.F., Shull, W.H.: Diffuse axonal injury in head trauma. J. Head Trauma Rehab. 18(4), 307–316 (2003)
Johnson, V.E., Stewart, W., Smith, D.H.: Axonal pathology in traumatic brain injury. Exp. Neurol. 246, 35–43 (2013)
Greve, M.W., Zink, B.J.: Pathophysiology of traumatic brain injury. Mt Sinai J. Med. 76, 97–104 (2009)
Park, E., Bell, J.D., Baker, A.J.: Traumatic brain injury: can the consequences be stopped? Can. Med. Assoc. J. (CMAJ) 178(9), 1163–1170 (2008)
Wolf, J.A., Stys, P.K., Lusardi, T., Meaney, D., Smith, D.H.: Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels. J. Neurosci. 21(6), 1923–1930 (2001)
Werner, C., Engelhard, K.: Pathophysiology of traumatic brain injury. Br. J. Anaesth. 99(1), 4–9 (2007)
Leestma, J.E.: Chapter 5—Forensic aspects of intracranial equilibria, Chap. 6—Physical injury to the nervous system. In: Forensic Neuropathology, 2nd edn. Taylor & Francis Group, LLC (2009) pp. 386–391, 425–550
Tandon, P.N., Ramamurthi, R.: Chapter 38—Traumatic intracerebral haematomas. In: Ramamurthi and Tandon’s Textbook of Neurosurgery, 3rd edn. Jaypee Brothers Medical Publishers (2012), pp. 446–447
McCord, J.M.: Iron, free radicals, and oxidative injury. J. Nutr. 134(11), 3171S–3172S (2004)
Meldrum, B.S.: Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J. Nutr. 130, 1007S–1015S (2000)
Hlatky, R., Valadka, A.B., Robertson, C.S.: Intracranial hypertension and cerebral ischemia after severe traumatic brain injury. Neurosurg. Focus J. Neurosurg. 14(4) (2003)
Botteri, M., Bandera, E., Minelli, C., Latronico, N.: Cerebral blood flow thresholds for cerebral ischemia in traumatic brain injury. A systematic review. Crit. Care Med. 36(11), 3089–3092 (2008)
Fitzpatrick, J.J., Wallace, M.: Encyclopedia of Nursing Research, 2nd edn. Springer, Berlin (2006), pp. 64–66
Raichle, M.E.: The pathophysiology of brain ischemia. Ann. Neurol. 13(1), 2–10 (1983)
Coles, J.P.: Regional ischemia after head injury. Curr. Opin. Crit. Care 10, 120–125 (2004)
Morganti-Kossmann, M.C., Rancan, M., Stahel, P.F., Kossmann, T.: Inflammatory response in acute traumatic brain injury: a double-edged sword. Curr. Opin. Crit. Care 8(2), 101–105 (2002)
Agur, A.M.R., Dalley, A.F.: Chapter 7—Head–Face and scalp. In: Grant’s Atlas of Anatomy, 13th edn. Lippincott Williams & Wilkins (2013), p. 642
Martini, F.H., Nath, J.L., Bartholomew, E.F.: Chapter 7—The Axis Skeleton, Chapter 13—The spinal cord, spinal nerves, and spinal reflexes, Chapter 14—The brain and cranial nerves. In: Fundamentals of Anatomy & Physiology, 9th edn. Pearson/Benjamin Cummings (2012), pp. 207–213, 226, 430–447, 462–463
Chen, Y., Ostoja-Starzewski, M.: MRI-based finite element modeling of head trauma: spherically focusing shear waves. Acta Mech. 213(1–2), 155–167 (2010)
Jaslow, C.R.: Mechanical properties of cranial sutures. J. Biomech. 23(4), 313–321 (1990)
Van De Graaff K.M.: Chapter 11—Nervous tissue and the central nervous system, Chapter 12—Peripheral nervous system. In: Human Anatomy, 6th edn. The McGraw-Hill (2001), pp. 378–388, 413–426
Poca, M.A., Sahuquillo, J., Mataró, M., Benejam, B., Arikan, F., Báguena, M.: Ventricular enlargement after moderate or severe head injury: a frequent and neglected problem. J. Neurotrauma 22(11), 1303–1310 (2005)
Kammersgaard, L.P., Linnemann, M., Tibæk, M.: Hydrocephalus following severe traumatic brain injury in adults. Incidence, timing, and clinical predictors during rehabilitation. NeuroRehabilitation 33(3), 473–480 (2013)
Zhang, L., Yang, K.H., King, A.I.: A proposed injury threshold for mild traumatic brain injury. J. Biomech. Eng. 126(2), 226–236 (2004)
Meaney, D.F., Smith, D.H.: Biomechanics of concussion. Clin. Sports Med. 30(1), 19-vii (2011)
Zhang, L., Yang, K.H., King, A.I.: Comparison of brain responses between frontal and lateral impacts by finite element modeling. J. Neurotrauma 18(1), 21–30 (2001)
Hardy, W.N., Mason, M.J., Foster, C.D., Chirag, S.S., Kopacz, J.M., Yang, K.H., King, A.I.: A study of the response of the human cadaver head to impact. Stapp Car Crash J. 51, 17–80 (2007)
Clark, J.M., Post, A., Hoshizaki, T.B., Gilchrist, M.D.: Determining the relationship between linear and rotational acceleration and MPS for different magnitudes of classified brain injury risk in ice hockey. In: International Research Council on the Biomechanics of Injury (IRCOBI), Lyon (France) (2015)
Ueno, K., Melvin, J.W.: Finite element model study of head impact based on hybrid III head acceleration: the effects of rotational and translational acceleration. J. Biomech. Eng. 117(3), 319–328 (1995)
Post, A., Hoshizaki, T.B.: Rotational acceleration, brain tissue strain, and the relationship to concussion. J. Biomech. Eng. 137(3), 030801-1–030801-8 (2015)
Rowson, S., Brolinson, G., Goforth, M., Dietter, D., Duma, S.: Linear and angular head acceleration measurements in collegiate football. J. Biomech. Eng. 131(6), 061016-1–061016-7 (2009)
Hardy, W.N.: A study of the response of the human cadaver head to impact. Ph.D. dissertation, Wayne State University, Detroit, Michigan (2007)
Brands, D.W.A.: Predicting brain mechanics during closed head impact: numerical and constitutive aspects. Ph.D. dissertation, Technische Universiteit Eindhoven, Eindhoven (2002)
Nusholtz, G.S., Lux, P., Kaiker, P.S., Janicki, M.A.: Head impact response—Skull deformation and angular accelerations. In: Proceedings of 28th Stapp Car Crash Conference. Society of Automotive Engineers, Warrendale, PA (1984)
Bilston, L.E.: Chapter 1—Introduction. In: Neural Tissue Biomechanics. Springer, Berlin (2013), p. 70
Schmitt, K., Niederer, P.F., Muser, M.H., Walz, F.: Trauma Biomechanics: Introduction to Accidental Injury. Springer, Berlin (2004)
Hertz, E.: A note on the head injury criterion (HIC) as a predictor of the risk of skull fracture. In: Association for the Advancement of Automotive Medicine Annual Conference, San Antonio, Texas (1993)
Newman, J.A.: Head injury criteria in automotive crash testing. In: Proceedings of the 27th Stapp Car Crash Conference, SAE Paper 801317 (1980)
Willinger, R., Baumgartner, D.: Human head tolerance limits to specific injury mechanisms. Int. J. Crashworthiness 8(6), 605–617 (2003)
Willinger, R., Baumgartner, D.: Numerical and physical modelling of the human head under impact: towards new injury criteria? Int. J. Veh. Des. 32(1–2), 94–115 (2003)
Kleiven, S.: Predictors for traumatic brain injuries evaluated through accident reconstructions. Stapp Car Crash J. 51, 81–114 (2007)
Monson, K.L., Goldsmith, W., Barbaro, N.M., Manley, G.T.: Axial mechanical properties of fresh human cerebral blood vessels. J. Biomech. Eng. 125(2), 288–294 (2003)
Lee, M.C., Haut, R.C.: Insensitivity of tensile failure properties of human bridging veins to strain rate: implications in biomechanics of subdural hematoma. J. Biomech. 22(6–7), 537–542 (1989)
Willinger, R., Kang, H.S., Diaw, B.: Three-dimensional human head finite-element model validation against two experimental impacts. Ann. Biomed. Eng. 27(3), 403–410 (1999)
Kleiven, S., von Holst, H.: Consequences of head size following trauma to the human head. J. Biomech. 35(2), 153–160 (2002)
Horgan, T.J., Gilchrist, M.D.: Influence of FE model variability in predicting brain motion and intracranial pressure changes in head impact simulations. Int. J. Crashworthiness 9(4), 401–418 (2004)
Chen, Y.: Biomechanical analysis of traumatic brain injury by MRI-based finite element modeling. Ph.D. dissertation, University of Illinois, Urbana-Champaign (2011)
Horgan, T.J., Gilchrist, M.D.: The creation of three-dimensional finite element models for simulating head impact biomechanics. Int. J. Crashworthiness 8(4), 353–366 (2003)
van Hoof, J., Worswick, M.J.: Combining head models with composite helmet models to simulate ballistic impacts, Report number 515882, Defence R&D Canada, Defence Research Establishment Valcartier (2000)
Tse, K.M., Tan, L.B., Lee, S.J., Lim, S.P., Lee, H.P.: Development and validation of two subject-specific finite element models of human head against three cadaveric experiments. Int. J. Numer. Meth. Biomed. Eng. 30(3), 397–415 (2014)
Ji, S., Zhao, W., Ford, J.C., Beckwith, J.G., Bolander, R.P., Greenwald, R.M., Flashman, L.A., Paulsen, K.D., McAlliste, T.W.: Group-wise evaluation and comparison of white matter fiber strain and maximum principal strain in sports-related concussion. J. Neurotrauma 32(7), 441–454 (2015)
Shugar, T.A., Katona, M.G.: Development of Finite Element Head Injury Model. J. Eng. Mech. Div. 101(3), 223–239 (1975)
Ward, C., Thompson, R.: The development of a detailed finite element brain model. In: 19th Stapp Car Crash Conference, SAE Paper No. 751163, San Diego, California (1975)
Ruan, J.S.: Impact biomechanics of head injury by mathematical modeling. Ph.D. dissertation, Wayne State University, Detroit, MI (1994)
Turquier, F., Kang, H., Trosseille, X., Willinger, R., Lavaste, F., Tarriere, C., Domont, A.: Validation study of a 3D finite element head model against experimental data. In: Proceedings of the 40th Stapp Car Crash conference, SAE Technical Paper 962431, Albuquerque, New Mexico (1996)
Mendis, K.K., Stalnaker, R.L., Advani, S.H.: A constitutive relationship for large deformation finite element modeling of brain tissue. J. Biomech. Eng. 117(4), 279–285 (1995)
Gefen, A., Margulies, S.S.: Are in vivo and in situ brain tissues mechanically similar? J. Biomech. 37(9), 1339–1352 (2004)
Yang, K.H., Hu, J., White, N.A., King, A.I., Chou, C.C., Prasad, P.: Development of numerical models for injury biomechanics research: a review of 50 years of publications in the Stapp car crash conference. Stapp Car Crash J. 50, 429–490 (2006)
Gefen, A., Gefen, N., Zhu, Q., Raghupathi, R., Margulies, S.: Age-dependent changes in material properties of the brain and braincase of the rat. J. Neurotrauma 20(11), 1163–1177 (2003)
Levchakov, A., Linder-Ganz, E., Raghupathi, R., Margulies, S.S., Gefen, A.: Computational studies of strain exposures in neonate and mature rat brains during closed head impact. J. Neurotrauma 23(10), 1570–1580 (2006)
Moore, D.F., Jérusalem, A., Nyein, M., Noels, L., Jaffee, M.S., Radovitzky, R.A.: Computational biology—Modeling of primary blast effects on the central nervous system. NeuroImage 47, T10–T20 (2009)
Power, E.D.: A nonlinear finite element model of the human eye to investigate ocular injuries from night vision goggles. M.S. thesis, Virginia Polytechnic Institute and State University, Blacksburg, Virginia (2001)
Sopher, R., Nixon, J., Gorecki, C., Gefen, A.: Exposure to internal muscle tissue loads under the ischial tuberosities during sitting is elevated at abnormally high or low body mass indices. J. Biomech. 43(2), 280–286 (2010)
Farvid, M.S., Ng, T.W.K., Chan, D.C., Barrett, P.H.R., Watts, G.F.: Association of adiponectin and resistin with adipose tissue compartments, insulin resistance and dyslipidaemia. Diabetes Obes. Metab. 7(4), 406–413 (2005)
Cortes, D.H., Jacobs, N.T., DeLucca, J.F., Elliott, D.M.: Elastic, permeability and swelling properties of human intervertebral disc tissues: a benchmark for tissue engineering. J. Biomech. 47(9), 2088–2094 (2014)
Little, J.P.: Finite element modelling of anular lesions in the lumbar intervertebral disc, Ph.D. dissertation, Queensland University of Technology, Brisbane, Queensland (2004)
Bao, C., Meng, Q.: Study on mechanical characteristics of lumbar spine for snatch action in weight lifting based on finite element method. Int. J. Sports Sci. Eng. 4(1), 048–052 (2010)
Greaves, C.Y., Gadala, M.S., Oxland, T.R.: A three-dimensional finite element model of the cervical spine with spinal cord: an investigation of three injury mechanisms. Ann. Biomed. Eng. 36(3), 396–405 (2008)
Soza, G., Grosso, R., Nimsky, C., Hastreiter, P., Fahlbusch, R., Greiner, G.: Determination of the elasticity parameters of brain tissue with combined simulation and registration. Int. J. Med. Robot. Comput. Assist. Surg. 1(3), 87–95 (2005)
Takhounts, E.G., Crandall, J., Kurosh, D.: On the importance of nonlinearity of brain tissue under large deformations. Stapp Car Crash J. 47, 79–92 (2003)
Sigal, I.A., Flanagan, J.G., Ethier, C.R.: Factors influencing optic nerve head biomechanics. Invest. Ophthalmol. Vis. Sci. 46(11), 4189–4199 (2005)
Nahum, A.M., Smith, R., Ward, C.C.: Intracranial pressure dynamics during head impact. In: 21st Stapp Car Crash Conference. Society of Automotive Engineers (SAE), SAE Paper No. 770922, pp. 339–366, San Diego, USA (1977)
Hardy, W.N., Foster, C.D., Mason, M.J., Yang, K.H., King, A.I., Tashman, S.: Investigation of head injury mechanisms using neutral density technology and high-speed biplanar X-ray. Stapp Car Crash J. 45, 337–368 (2001)
Kulkarni, S.G., Gao, X.L., Horner, S.E., Zheng, J.Q., David, N.V.: Ballistic helmets—Their design, materials, and performance against traumatic brain injury. Compos. Struct. 101, 313–331 (2013)
Yang, J., Dai, J.: Simulation-based assessment of rear effect to ballistic helmet impact. Comput. Aided Des. Appl. 7(1), 59–73 (2010)
Aare, M., Kleiven, S.: Evaluation of head response to ballistic helmet impacts using the finite element method. Int. J. Impact Eng. 34, 596–608 (2007)
Chang, F.K., Chang, K.Y.: A progressive damage model for laminated composites containing stress concentrations. J. Compos. Mater. 21(9), 834–855 (1987)
Abrate, S.: Matrix cracking in laminated composites: a review. Compos. Eng. 1(6), 337–353 (1991)
Harris, B.: Engineering composite materials. The Institute of Metals, London (1999)
Chang, F.K., Chen, M.H.: The in situ ply shear strength distributions in graphite/epoxy laminated composites. J. Compos. Mater. 21, 708–733 (1987)
David, N.V., Gao, X.L., Zheng, J.Q.: Ballistic resistant body armor: contemporary and prospective materials and related protection mechanisms. Appl. Mech. Rev. 62(5), 050802-1–050802-20 (2009)
Haque, B.Z.G., Gillespie, J.W.: A new penetration equation for ballistic limit analysis. J. Thermoplast. Compos. Mater. 28(7), 950–972 (2013)
Zhang, L., Makwana, R., Sharma, S.: Brain response to primary blast wave using validated finite element models of human head and advanced combat helmet. Front. Neurol. 4(88) (2013)
Tse, K.M., Tan, L.B., Yang, B., Tan, V.B.C., Lim, S.P., Lee, H.P.: Ballistic impacts of a Full-Metal Jacketed (FMJ) bullet on a validated Finite Element (FE) model of helmet-cushion-head. In: The 5th International Conference on Computational Methods (ICCM), Cambridge, England (2014)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Friedman, R., Epstein, Y., Gefen, A. (2016). Traumatic Brain Injury in the Military: Biomechanics and Finite Element Modelling. In: Gefen, A., Epstein, Y. (eds) The Mechanobiology and Mechanophysiology of Military-Related Injuries. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 19. Springer, Cham. https://doi.org/10.1007/8415_2016_189
Download citation
DOI: https://doi.org/10.1007/8415_2016_189
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-33010-5
Online ISBN: 978-3-319-33012-9
eBook Packages: EngineeringEngineering (R0)