Abstract
Among the many challenges to health, infectious diseases stand out for their ability to have a profound impact on humans and animals. The recent years have witnessed an increasing number of novel infectious diseases. The numerous examples of infections which originated from animals suggest that the zoonotic pool is an important and potentially rich source of emerging diseases. Since emergence and re-emergence of pathogens, and particularly zoonotic agents, occur at unpredictable rates in animal and human populations, infectious diseases will constitute a significant challenge for the public health and animal health communities in the twenty-first century. The African continent suffers from one of the highest burdens of infectious diseases of humans and animals in the world but has the least capacity for their detection, identification and monitoring. Lessons learnt from recent zoonotic epidemics in Africa and elsewhere clearly indicate the need for coordinated research, interdisciplinary centres, response systems and infrastructures, integrated surveillance systems and workforce development strategies. More and stronger partnerships across national and international sectors (human health, animal health, environment) and disciplines (natural and social sciences) involving public, academic and private organisations and institutions will be required to meet the present and future challenges of infectious diseases. In order to strengthen the efficiency of early warning systems, monitoring trends and disease prediction and timely outbreak interventions for the benefit of the national and international community, it is essential that each nation improves its own capacity in disease recognition and laboratory competence. The SACIDS, a One Health African initiative linking southern African academic and research institutions in smart partnership with centres of science excellence in industrialised countries as well as international research centres, strives to strengthen Africa’s capacity to detect, identify and monitor infectious diseases of humans and animals, to better manage health and socio–economic risks posed by them, and to improve research capacity in investigating the biologic, socio–economic, ecologic and anthropogenic factors responsible for emergence and re-emergence of infectious diseases.
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References
Ishii A, Thomas Y, Moonga L, Nakamura I, Ohnuma A, Hang’ombe BM, Takada A, Mweene A, Sawa H (2011) Novel arena virus, Zambia. Emerging infectious diseases, 17:1921–1924
Brett NA, Weyer J, Paweska J, Nkosi D, Leman P, Tint KS, Blumberg L (2011) Outbreak of Rift Valley fever virus affecting veterinarians and farmers in South Africa, 2008, S Afr Med J 101:263–266
Briese T, Paweska JT, McMullan LK, Hutchison SK, Street C, Palacios G, Khristova ML, Weyer J, Swanepoel R, Egholm M, Nichol ST, Lipkin WI (2009) Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern Africa. PLoS Pathog 5:e1000455
Buchmeier MJ, de la Torre J.-C, Peters CJ (2007) Arenaviridae: the viruses and their replication. In: Knipe DM, Howley PM (eds) Fields Virology, 5th ed. Philadelphia: Lippencott Williams & Wilkins, Hagerstown pp1791–1827
Brownlie J, Peckham C, Waage J, Woolhouse M, Lyall C, Meagher L. Tait J, Baylis M, Nicoll A (2006) Foresight. Infectious diseases: preparing for the future. Future Threats. Office of Science and Innovation, London p 1–83. http://www.bis.gov.uk/assets/bispartners/foresight/docs/infectious-diseases/t1.pdf. Accessed January 2012
Brownlie J, Morgan D, Otim-Nape W, Rweyemamu M, Serwadda D, Waage J (2005) Infectious diseases in Africa: using science to fight the evolving threat report of a pan-African workshop in Entebbe, Uganda, August 2005. Office of Science and Innovation, London. http://www.bis.gov.uk/assets/bispartners/foresight/docs/infectious-diseases/a4.pdf (Accessed May 2012)
Charrel RN, de Lamballerie X, Emonet S (2008) Phylogeny of the genus Arenavirus. Curr Opin Microbiol 11:362–368
European Commission (2010) Outcome and impact assessment of the global response to the avian influenza crisis 2005–2010. Publications Office of the European Union, Luxembourg
FAO/OIE/WHO (2008) Contributing to one world, one health: a strategic framework for reducing the risks of infectious diseases at the animal-human-ecosystems Interface. OIE/WHO/UNICEF/World Bank and UN system influenza coordination, international ministerial conference on avian and pandemic influenza. Sharm El-Sheikh, October 14, 2008. http://un-influenza.org/files/OWOH_14Oct08.pdf Accessed January, 2012
Grobbelaar AA, Weyer J, Leman PA, Kemp A, Paweska JT, Swanepoel R (2011) Molecular epidemiology of Rift Valley fever virus. Emerg Infect Dis 17:2270–2276
Hang’ombe BM, Nakamura I, Samui KL, Kaile D, Mweene AS, Kilonzo BS, Sawa H, Sugimoto C, Wren BW (2012) Evidence of Yersinia pestis DNA from fleas in an endemic plague area of Zambia. BMC research notes. 5:72
Hinnebusch JB, Gage KL, Schwan TG (1998) Estimation of vector infectivity rates for plague by means of a standard curve-based competitive polymerase chain reaction method to quantify Yersinia pestis in fleas. 1998. Am J Trop Med Hyg, 58:562–569
Ishii A, Thomas Y, Moonga L, Nakamura I, Ohnuma A, Hang’omebe A, Takada A, Mweene B, Sawa H (2011) Novel arenavirus, Zambia. Emerg Infect Dis 17:1921–1924
Jansen van Vuren P, WeyerJ, Kemp A, le Roux C, Leman P, Grobbelaar A, Lekhuleni P, Dermaux-Msimang V, Archer B, Thomas J, Blumberg L, Paweska J (2012) Viral haemorrhagic fever outbreaks, South Africa, 2011. National Health Laboratory Service, National Institute for Communicable Diseases 1 April, 2012, Commun Dis Surveill Bull 10(1):1–5
Jonas O (2012) Economics of one health. Presentation to the one health summit 2012. Davos, 19–23 February, 2012
Jones KE, Patel N, Levy MA, Storeygard AD, Balk JL, Gittleman, Daszak P (2008) Global trends in emerging infectious diseases. Nature 451:990–993
Kasanga CJ, Sallu R, Kivaria F, Mkama M, Masambu J, Yongolo M et al (2012) Foot-and-mouth disease virus serotypes detected in Tanzania from 2003 to 2010: Conjectured status and future prospects’, Onderstepoort J Vet Res 79(2), Art. #462, 4 pages. http://www.dx.doi.org/10.4102/ojvr.v79i2.462
King DA, Peckham C, Waage JK, Brownlie J, Woolhouse M (2006) Infectious diseases—Preparing for the future, 8th Sept 2006. Science 303:1392–1393
King L (2008) The convergence of human and animal health one world–one health. UMN Workshop; Minneapolis, 14 May 2008
Knowles NJ, Samuel AR (2003) Molecular epidemiology of foot-and-mouth disease virus. Virus Res 91:65–80
Kock RA, Kock MD, Cleaveland S, Thomson G (2010) Health and disease in wild rangelands. In: Wild Rangelands Conserving wildlife while maintaining livestock in semi-arid ecosystems. Du Toit JT, Kock RA, Deutsch JC (eds). Wiley Blackwell Oxford pp 98–128
Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJL (2006) Global and Regional Burden of Disease and Risk Factors, 2001: systematic analysis of population health data. The Lancet 367:1747–1757
Marcotty T, Matthys F, Godfroid J, Rigouts L, Ameni G, van Pittius NG, Kazwala R, Muma J, van Helden P, Walravens K, de Klerk LM, Geoghegan C, Mbotha D, Otte M, Amenu K, bu Samra N, Botha C, Ekron M, Jenkins A, Jori F, Kriek N, McCrindle C, Michel A, Morar D, Roger F, Thys E, van den Bossche P (2009) Zoonotic tuberculosis and brucellosis in Africa: neglected zoonoses or minor public-health issues? The outcomes of amulti-disciplinary workshop. Ann Trop Med Parasitol 103:401–411
Muyembe-Tamfum JJ, Mulangu S, Masumu J, Kayembe JM, Paweska JT (2012) Ebola virus outbreaks in Africa: past and present. Onderstepoort J vet Res 79(2), Art. #451, 8 pages. http://dx.doi.org/10.4102/ojvr.v79i2.451
Parkes MW, Bienen L, Breilh J, Hsu L-N, McDonald M, Patz JA, Rosenthal JP, Sahani M, Sleigh A, Waltner-Toews D, Yassi A (2005) All hands on deck: transdisciplinary approaches to emerging infectious disease. EcoHealth 2:258–272
Paweska JT, Sewlall NH, Ksiazek TG, Blumberg LH, Hale MJ, Lipkin WI, Weyer J, Nichol PE, Rollin LK, McMullan CD, Paddock T, Briese J, Mnyaluza T -H., Dinh V, Mukonka P, Ching A, Duse G, Richards G, de Jong C, Cohen B, Ikalafeng C, Mugero C, Asomugha MM, Malotle DM, Nteo E, Misiani R, Swanepoel SR, Zaki, Members of the outbreak control, and investigation teams (2009) Nosocomial outbreak of novel arenavirus infection, Southern Africa. Emerg Infect Dis 15:1598–1602
Pepin M, Bouloy M, Bird B, Kemp A, Paweska J (2010) Rift Valley fever virus (Bunyaviridae: Phlebovirus): an update on pathogenesis, molecular epidemiology, vectors, diagnostics and prevention. Vet Res 41:61. doi:10.1051/vetres/2010033
Perry BD, Rich KM (2007) Poverty impacts of foot-and-mouth disease and the poverty reduction implications of its control, Veterinary Record 2007;160:238–241
Rushton J, Häsler B, de Haan N, Rushton R (2012). Economic benefits/drivers of a “one health” approach: why should anyone invest? Onderstepoort J vet Res 79(2), Art. #461, 5 pages. http://dx.doi.org/10.4102/ojvr.v79i2.461
Rweyemamu M, Otim-Nape W, Serwadda D (2006) Foresight. infectious diseases: preparing for the future, Africa Office of Science and Innovation, London p1–120. http://www.bis.gov.uk/assets/bispartners/foresight/docs/infectious-diseases/a1_id_africa.pdf. Accessed January 2012
Rweyemamu M, Roeder P, MacKay D, Sumption K, Brownlie J, Leforban Y (2008) Planning for the progressive control of foot-and-mouth disease worldwide. transboundary and emerging diseases.55:73–87
Rweyemamu MM, Paweska J, Kambarage D, Namuba F (2012) Towards One Africa, One Health: the SACIDS one health focus on infectious diseases. Onderstepoort J vet Res 79(2), Art. #449, 2 pages. http://dx.doi.org/10.4102/ojvr.v79i2.449
Stenseth NC, Atshabar BB, Begon M, Belmain SR, Bertherat E, Carniel E, Gage KL, Leirs H, Rahalison L (2008) Plague: past, present and future. PLoS Med 5:e3. doi:10.1371/journal.pmed.005003
Swanepoel R, Paweska JT (2011) Rift Valley fever. Oxford textbook of zoonoses: biology, clinical practise, and public health control 2nd edn. In: Palmer SR, Soulsby L, Torgerson PR, Brown DWG (eds), Oxford University Press, Oxford, pp 421–431
Saijo M, Niikura M, Ikegami T, Kurane I, Kurata T, Morikawa S (2006) Laboratory diagnostic systems for Ebola and Marburg hemorrhagic fevers developed with recombinant proteins. Clin Vaccine Immunol 13:444–51
Smith KR, Corvalan CF, Kjellstrom T (1999) How much ill health is attributable to environmental factors? Epidemiology 10:573–584
Vosloo W, Baston ADS, Sangare O, Hargreaves SK, Thomas GR (2002) Review of the status and control of foot and mouth disease in sub-saharan Africa. Rev. Sci. Tech. Off. Int. Epizoot. 21:437–449
Wenger E, McDermott R, Synder W (2002) Cultivating Communities of Practice: a guide to managing knowledge. Harvard Business School Press, Boston
WHO (1978a) Ebola haemorrhagic fever in Sudan. 1976. Bull World Health Organ 56:247–270
WHO (1978b) Ebola haemorrhagic fever in Zaire. 1976. Bull World Health Organ 56:271–293
WHO (2000) Human plague in 1998 and 1999. Weekly Epidemiol Rec 75:338–343
Woolhouse MEJ (2008) Epidemiology: Emerging diseases go global. Nature 451:898–899
World Bank (2010) People, pathogens, and our planet. Volume one: towards a one health approach for controlling zoonotic diseases. © World Bank
Zinsstag J, Schelling E, Roth F, Bonfoh B, de Savigny D (2007) And Tanner, M. Emerg Infect Dis 13:527–531
Zinsstag J, Schelling E, Waltner-Toews D, Tanner M (2011) From “one medicine” to “one health” and systemic approaches to health and well-being. Prev Vet Med 101:148–56
Acknowledgments
We acknowledge the financial support from the Wellcome Trust, Rockefeller Foundation, Google Foundation and the UK Foresight programme. As a Virtual Centre, SACIDS heavily depends on the commitment and support of the host institution (Sokoine University of Agriculture) and all the member institutions in the DRC, Mozambique, South Africa, Tanzania and Zambia as well as the mentoring support and commitment of our Smart Partners, especially the London School of Hygiene and Tropical Medicine, the Royal Veterinary College and the London International Development Centre as well as the International Livestock Research Institute (ILRI).
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Rweyemamu, M. et al. (2012). Development of a One Health National Capacity in Africa. In: Mackenzie, J., Jeggo, M., Daszak, P., Richt, J. (eds) One Health: The Human-Animal-Environment Interfaces in Emerging Infectious Diseases. Current Topics in Microbiology and Immunology, vol 366. Springer, Berlin, Heidelberg. https://doi.org/10.1007/82_2012_244
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DOI: https://doi.org/10.1007/82_2012_244
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