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Visceral Pain

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Behavioral Neurobiology of Chronic Pain

Part of the book series: Current Topics in Behavioral Neurosciences ((CTBN,volume 20))

Abstract

Modeling visceral pain requires an appreciation of the underlying neurobiology of visceral sensation, including characteristics of visceral pain that distinguish it from pain arising from other tissues, the unique sensory innervation of visceral organs, the functional basis of visceral pain, and the concept of viscero-somatic and viscero-visceral convergence. Further, stimuli that are noxious when applied to the viscera are different than stimuli noxious to skin, muscle, and joints, thus informing model development and assessment. Visceral pain remains an important and understudied area of pain research and basic science knowledge and mechanisms acquired using animal models can translate into approaches that can be applied to the study and development of future therapeutics.

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Authors and Affiliations

  1. Center for Pain Research, Department of Anesthesiology, School of Medicine, University of Pittsburgh, W1444 BST-Starzl, 200 Lothrop St., Pittsburgh, PA, 15213, USA

    Erica S. Schwartz & G. F. Gebhart

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  1. Erica S. Schwartz
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  2. G. F. Gebhart
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Correspondence to G. F. Gebhart .

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Editors and Affiliations

  1. University of Kentucky Medical Center, Lexington, Kentucky, USA

    Bradley K. Taylor

  2. Centre for Pain Research, National University of Ireland, Galway, Ireland

    David P. Finn

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Schwartz, E.S., Gebhart, G.F. (2014). Visceral Pain. In: Taylor, B., Finn, D. (eds) Behavioral Neurobiology of Chronic Pain. Current Topics in Behavioral Neurosciences, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7854_2014_315

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