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Sex, Drugs, and Violence: Neuromodulation of Attachment and Conflict in Voles

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Neuroscience of Aggression

Part of the book series: Current Topics in Behavioral Neurosciences ((CTBN,volume 17))

Abstract

Prairie voles (Microtus ochrogaster) are a rodent species that display socially monogamous pair-bonds, a behavior illustrated by several types of social interactions such as mating-induced partner preference, selective aggression toward conspecific strangers, and bi-parental care. Therefore, this species has provided an excellent opportunity for the study of pair-bonding and its underlying neurochemical mechanisms. This chapter discusses the utility of this unique rodent in the study of attachment and conflict, and reviews recent findings illustrating the neuromodulatory mechanisms underlying mating-induced partner preference and aggression. Finally, implications of research using this animal model in human mental health are also discussed.

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Acknowledgments

The work reviewed in this chapter was supported by National Institutes of Health grants MHF31-79600 to KLG, MHR01-58616, DAR01-19627, & DAK02-23048 to ZXW, and NIH Program Training Grant T32 NS-07437.

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The author declares no competing financial interests.

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  1. Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA, 02115, USA

    Kyle L. Gobrogge

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  1. Moses Hunt Professor of Psychology, Psychiatry, Pharmacol & Neurosci, Tufts University, Medford, Massachusetts, USA

    Klaus A. Miczek

  2. Dept of Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany

    Andreas Meyer-Lindenberg

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Gobrogge, K.L. (2013). Sex, Drugs, and Violence: Neuromodulation of Attachment and Conflict in Voles. In: Miczek, K., Meyer-Lindenberg, A. (eds) Neuroscience of Aggression. Current Topics in Behavioral Neurosciences, vol 17. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7854_2013_264

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