Abstract
Attention-deficit hyperactivity disorder (ADHD) is one of the most common neuropsychiatric disorders with childhood onset, having a chronic course associated with high dysfunction and morbidity throughout life. Despite significant advances in our understanding of the neurobiological underpinnings of the disorder, diagnosis of ADHD remains strictly clinical and is based on behavioral symptoms of inattention, impulsivity, and hyperactivity. In this chapter, we review the diagnostic process and current controversies in the diagnosis of ADHD, discuss the clinical presentation of the disorder across the lifespan, and examine the patterns of comorbidity and the longitudinal predictors of outcomes. We conclude by pointing out some of the challenges that need to be addressed in future classifications systems to improve the characterization and validity of the diagnosis of ADHD.
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Abbreviations
- ADHD:
-
Attention-deficit hyperactivity disorder
- APA:
-
American Psychiatric Association
- CD:
-
Conduct disorder
- DSM:
-
Diagnostic and Statistical Manual (of Mental Disorders)
- ICD:
-
International Classification of Diseases
- ODD:
-
Oppositional defiant disorder
References
American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders (4th edn, Text Revision) (DSM-IV-TR). American Psychiatric Association, Washington, DC
Asherson P, Chen W, Craddock B, Taylor E (2007) Adult attention-deficit hyperactivity disorder: recognition and treatment in general adult psychiatry. Br J Psychiatry 190:4–5
Bagwell CL, Molina BSG, Pelham WE, Hoza B (2001) Attention-deficit hyperactivity disorder and problems in peer relations: Predictions from childhood to adolescence. J Am Acad Child Adolesc Psychiatry 40:1285–1292
Barkley RA, Cox D (2007) A review of driving risks and impairments associated with attention-deficit/hyperactivity disorder and the effects of stimulant medication on driving performance. J Safety Res 38:113–128
Barkley RA, Fischer M (2010) The unique contribution of emotional impulsiveness to impairment in major life activities in hyperactive children as adults. J Am Acad Child Adolesc Psychiatry 49:503–513
Barkley RA, Murphy KR (2010a) Deficient emotional self-regulation in adults with attention-deficit/hyperactivity disorder (ADHD): the relative contributions of emotional impulsiveness and ADHD symptoms to adaptive impairments in major life activities. Journal of ADHD and Related Disorders 1:5–28
Barkley RA, Murphy KR (2010b) Impairment in occupational functioning and adult ADHD: the predictive utility of executive function (EF) ratings versus EF tests. Arch Clin Neuropsychol 25:157–173
Barkley RA, Fischer M, Smallish L, Fletcher K (2002) The persistence of attention-deficit/hyperactivity disorder into young adulthood as a function of reporting source and definition of disorder. J Abnorm Psychol 111:279–289
Barkley RA, Fischer M, Smallish L, Fletcher K (2003) Does the treatment of attention-deficit/hyperactivity disorder with stimulants contribute to drug use/abuse? A 13-year prospective study. Pediatrics 111:97–109
Biederman J, Faraone S, Milberger S, Guite J, Mick E, Chen L, Mennin D, Marrs A, Oullette C, Moore P, Spencer T, Norman D, Wilens T, Kraus I, Perrin J (1996) A prospective 4-year follow-up study of attention-deficit hyperactivity and related disorders. Arch Gen Psychiatry 53:437–446
Biederman J, Wilens TE, Mick E, Faraone SV, Spencer T (1998) Does attention-deficit hyperactivity disorder impact the developmental course of drug and alcohol abuse and dependence? Biol Psychiatry 44:269–273
Biederman J, Petty CR, Dolan C, Hughes S, Mick E, Monuteaux MC, Faraone SV (2008) The long-term longitudinal course of oppositional defiant disorder and conduct disorder in ADHD boys: findings from a controlled 10-year prospective longitudinal follow-up study. Psychol Med 38:1027–1036
Biederman J, Petty CR, Evans M, Small J, Faraone SV (2010) How persistent is ADHD? A controlled 10-year follow-up study of boys with ADHD. Psychiatry Res 177:299–304
Bussing R, Zima BT, Perwien AR (2000) Self-esteem in special education children with ADHD: relationship to disorder characteristics and medication use. J Am Acad Child Adolesc Psychiatry 39:1260–1269
Bussing R, Mason DM, Bell L, Porter P, Garvan C (2010) Adolescent outcomes of childhood attention-deficit/hyperactivity disorder in a diverse community sample. J Am Acad Child Adolesc Psychiatry 49:595–605
Byrne JM, Bawden HN, DeWolfe NA, Beattie TL (1998) Clinical assessment of psychopharmacological treatment of preschoolers with ADHD. J Clin Exp Neuropsychol 20:613–627
Chi TC, Hinshaw SP (2002) Mother-child relationships of children with ADHD: the role of maternal depressive symptoms and depression-related distortions. J Abnorm Child Psychol 30:387–400
Connor DF (2002) Preschool attention deficit hyperactivity disorder: a review of prevalence, diagnosis, neurobiology, and stimulant treatment. J Dev Behav Pediatr 23:S1–S9
Daley D, Birchwood J (2010) ADHD and academic performance: why does ADHD impact on academic performance and what can be done to support ADHD children in the classroom? Child Care Health Dev 36:455–464
Daviss WB (2008) A review of co-morbid depression in pediatric ADHD: etiologies, phenomenology, and treatment. J Child Adolesc Psychopharmacol 18:565–571
DuPaul GJ, Stoner GD (2003) ADHD in the schools: assessment and intervention strategies, 2nd edn. Guilford Press, New York
DuPaul GJ, McGoey KE, Eckert TL, VanBrakle J (2001) Preschool children with attention-deficit/hyperactivity disorder: impairments in behavioral, social, and school functioning. J Am Acad Child Adolesc Psychiatry 40:508–515
Eakin L, Minde K, Hechtman L, Ochs E, Krane E, Bouffard R, Greenfield B, Looper K (2004) The marital and family functioning of adults with ADHD and their spouses. J Atten Disord 8:1–10
Edwards G, Barkley RA, Laneri M, Fletcher K, Metevia L (2001) Parent-adolescent conflict in teenagers with ADHD and ODD. J Abnorm Child Psychol 29:557–572
Fabiano GA, Pelham WE, Coles EK, Gnagy EM, Chronis-Tuscano A, O'Connor BC (2009) A meta-analysis of behavioral treatments for attention-deficit/hyperactivity disorder. Clin Psychol Rev 29:129–140
Faraone SV, Biederman J, Mick E (2006) The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies. Psychol Med 36:159–165
Fergusson DM, Horwood LJ, Ridder EM (2007) Conduct and attentional problems in childhood and adolescence and later substance use, abuse and dependence: Results of a 25-year longitudinal study. Drug Alcohol Depend 88:S14–S26
Fischer M, Barkley RA (2003) Young adult follow-up of hyperactive children: self-reported psychiatric disorders, comorbidity, and the role of childhood conduct problems and teen CD (vol 30, pg 463, 2002). J Abnorm Child Psychol 31:563–563
Fischer M, Barkley RA, Smallish L, Fletcher K (2007) Hyperactive children as young adults: driving abilities, safe driving behavior, and adverse driving outcomes. Accid Anal Prev 39:94–105
Frazier TW, Youngstrom EA (2006) Evidence-based assessment of attention-deficit/hyperactivity disorder: using multiple sources of information. J Am Acad Child Adolesc Psychiatry 45:614–620
Galera C, Melchior M, Chastang JF, Bouvard MP, Fombonne E (2009) Childhood and adolescent hyperactivity-inattention symptoms and academic achievement 8 years later: the GAZEL Youth study. Psychol Med 39:1895–1906
Gaub M, Carlson CL (1997) Behavioral characteristics of DSM-IV ADHD subtypes in a school-based population. J Abnorm Child Psychol 25:103–111
Goldman LS, Genel M, Bezman RJ, Slanetz PJ, Amer Med A (1998) Diagnosis and treatment of attention-deficit/hyperactivity disorder in children and adolescents. JAMA 279:1100–1107
Graetz BW, Sawyer MG, Baghurst P (2005) Gender differences among children with DSM-IV ADHD in Australia. J Am Acad Child Adolesc Psychiatry 44:159–168
Greenhill LL, Posner K, Vaughan BS, Kratochvil CJ (2008) Attention deficit hyperactivity disorder in preschool children. Child Adolesc Psychiatr Clin N Am 17:347
Hinshaw SP (2003) Impulsivity, emotion regulation, and developmental psychopathology: specificity versus generality of linkages. Roots of Mental Illness in Children 1008:149–159
Huizink AC, van Lier PAC, Crijnen AAM (2009) Attention deficit hyperactivity disorder symptoms mediate early-onset smoking. Eur Addict Res 15:1–9
Kessler RC, Adler L, Barkley R, Biederman J, Conners CK, Demler O, Faraone SV, Greenhill LL, Howes MJ, Secnik K, Spencer T, Ustun TB, Walters EE, Zaslavsky AM (2006) The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication. Am J Psychiatry 163:716–723
Kieling C, Goncalves RRF, Tannock R, Castellanos FX (2008) Neurobiology of attention deficit hyperactivity disorder. Child Adolesc Psychiatr Clin N Am 17:285
Kieling C, Kieling RR, Rohde LA, Frick PJ, Moffitt T, Nigg JT, Tannock R, Castellanos FX (2010) The age at onset of attention deficit hyperactivity disorder. Am J Psychiatry 167:14–16
Kieling RR, Szobot CM, Matte B, Coelho R, Kieling C, Pechansky F, Rohde LA (2011) Mental disorders and delivery motorcycle drivers (motoboys): a dangerous association. Eur Psychiatry (Paris) 26:23–27
Kofler MJ, Rapport MD, Bolden J, Sarver DE, Raiker JS (2010) ADHD and working memory: the impact of central executive deficits and exceeding storage/rehearsal capacity on observed inattentive behavior. J Abnorm Child Psychol 38:149–161
Kutcher S, Aman M, Brooks SJ, Buitelaar J, van Daalen E, Fegert J, Findling RL, Fisman S, Greenhill LL, Huss M, Kusumakar V, Pine D, Taylor E, Tyano S (2004) International consensus statement on attention-deficit/hyperactivity disorder (ADHD) and disruptive behaviour disorders (DBDs): clinical implications and treatment practice suggestions. Eur Neuropsychopharmacol 14:11–28
Lahey BB, Pelham WE, Loney J, Lee SS, Willcutt E (2005) Instability of the DSM-IV subtypes of ADHD from preschool through elementary school. Arch Gen Psychiatry 62:896–902
Langley K, Fowler T, Ford T, Thapar AK, van den Bree M, Harold G, Owen MJ, O'Donovan MC, Thapar A (2010) Adolescent clinical outcomes for young people with attention-deficit hyperactivity disorder. Br J Psychiatry 196:235–240
Loe IM, Feldman HM (2007) Academic and educational outcomes of children with ADHD. J Pediatr Psychology 32:643–654
Mannuzza S, Klein RG, Truong NL, Moulton JL, Roizen ER, Howell KH (2008) Age of methylphenidate treatment initiation in children with ADHD and later substance abuse: prospective follow-up into adulthood. Am J Psychiatry 165:604–609
Marks DJ, Mlodnicka A, Bernstein M, Chacko A, Rose S, Halperin JM (2009) Profiles of service utilization and the resultant economic impact in preschoolers with attention deficit/hyperactivity disorder. J Pediatr Psychology 34:681–689
McGoey KE, Eckert TL, DuPaul GJ (2002) Early intervention for preschool-age children with ADHD: a literature review. J Emot Behav Disord 10:14–28
Molina BSG, Pelham WE (2003) Childhood predictors of adolescent substance use in a longitudinal study of children with ADHD. J Abnorm Psychol 112:497–507
Newcorn JH, Halperin JM, Jensen PS, Abikoff HB, Arnold LE, Cantwell DP, Conners CK, Elliott GR, Epstein JN, Greenhill LL, Hechtman L, Hinshaw SP, Hoza B, Kraemer HC, Pelham WE, Severe JB, Swanson JM, Wells KC, Wigal T, Vitiello B (2001) Symptom profiles in children with ADHD: effects of comorbidity and gender. J Am Acad Child Adolesc Psychiatry 40:137–146
Nijmeijer JS, Minderaa RB, Buitelaar JK, Mulligan A, Hartman CA, Hoekstra PJ (2008) Attention-deficit/hyperactivity disorder and social dysfunctioning. Clin Psychol Rev 28:692–708
Parens E, Johnston J (2009) Facts, values, and attention-deficit hyperactivity disorder (ADHD): an update on the controversies. Child Adolesc Psychiatry Ment Health 3:1
Pliszka S, Bernet W, Bukstein O, Walter HJ, Arnold V, Beitchman J, Benson RS, Chrisman A, Farchione T, Hamilton J, Keable H, Kinlan J, McClellan J, Rue D, Schoettle U, Shaw JA, Stock S, Ptakowski KK, Medicus J (2007) Practice parameter for the assessment and treatment of children and adolescents with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 46:894–921
Polanczyk G, Rohde LA (2007) Epidemiology of attention-deficit/hyperactivity disorder across the lifespan. Curr Opin Psychiatry 20:386–392
Polanczyk G, de Lima MS, Horta BL, Biederman J, Rohde LA (2007) The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry 164:942–948
Posner K, Melvin GA, Murray DW, Gugga SS, Fisher P, Skrobala A, Cunningham C, Vitiello B, Abikoff HB, Ghuman JK, Kollins S, Wigal SB, Wigal T, McCracken JT, McGough JJ, Kastelic E, Boorady R, Davies M, Chuang SZ, Swanson JM, Riddle MA, Greenhill LL (2007) Clinical presentation of attention-deficit/hyperactivity disorder in preschool children: The preschoolers with attention-deficit/hyperactivity treatment study (PATS). J Child Adolesc Psychopharmacol 17:547–562
Ramtekkar UP, Reiersen AM, Todorov AA, Todd RD (2010) Sex and age differences in attention-deficit/hyperactivity disorder symptoms and diagnoses: implications for DSM-V and ICD-11. J Am Acad Child Adolesc Psychiatry 49:217–228
Rohde LA (2008) Is there a need to reformulate attention deficit hyperactivity disorder criteria in future nosologic classifications? Child Adolesc Psychiatr Clin N Am 17:405
Rohde LA, Halpern R (2004) Recent advances on attention deficit/hyperactivity disorder. J Pediatr (Rio J) 80:S61–S70
Sayal K, Goodman R (2009) Do parental reports of child hyperkinetic disorder symptoms at school predict teacher ratings? Eur Child Adolesc Psychiatry 18:336–344
Sayal K, Taylor E (2005) Parent ratings of school behaviour in children at risk of attention deficit/hyperactivity disorder. Acta Psychiatr Scand 111:460–465
Simon V, Czobor P, Balint S, Meszaros A, Bitter I (2009) Prevalence and correlates of adult attention-deficit hyperactivity disorder: meta-analysis. Br J Psychiatry 194:204–211
Smidts DP, Oosterlaan J (2007) How common are symptoms of ADHD in typically developing preschoolers? a study on prevalence rates and prenatal/demographic risk factors. Cortex 43:710–717
Sowerby P, Tripp G (2009) Evidence-based assessment of attention-deficit/hyperactivity disorder (ADHD). In: Matson JL, Andrasik F, Matson ML (eds) Assessing childhood psychopathology and developmental disabilities. Springer, New York, pp 209–239
Spira EG, Fischel JE (2005) The impact of preschool inattention, hyperactivity, and impulsivity on social and academic development: a review. J Child Psychol Psychiatry 46:755–773
Stein MA (2008) Impairment associated with adult ADHD. CNS Spectr 13:9–11
Szobot CM, Bukstein O (2008) Attention deficit hyperactivity disorder and substance use disorders. Child Adolesc Psychiatr Clin N Am 17:309
Weiss MD, Weiss JR (2004) A guide to the treatment of adults with ADHD. J Clin Psychiatry 65:27–37
Whitinger NS, Langley K, Fowler TA, Thomas HV, Thapar A (2007) Clinical precursors of adolescent conduct disorder in children with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 46:179–187
WHO (1993) The ICD-10 classification of mental and behavioural disorders: diagnostic criteria for research. WHO, Geneva
Wilens TE, Biederman J, Brown S, Tanguay S, Monuteaux MC, Blake C, Spencer TJ (2002) Psychiatric comorbidity and functioning in clinically referred preschool children and school-age youths with ADHD. J Am Acad Child Adolesc Psychiatry 41:262–268
Willcutt EG, Nigg JT, Pennington B, Solanto MV, Rohde LA, Tannock R, Loo SK, Carlson CL, McBurnett K, Lahey BB. Validity of DSM-IV attention–deficit/hyperactivity disorder symptom dimensions and subtypes. Under review edn
Wilson JJ, Levin FR (2001) Attention deficit hyperactivity disorder (ADHD) and substance use disorders. Curr Psychiatry Rep 3:497–506
Yochman A, Ornoy A, Parush S (2006) Co-occurrence of developmental delays among preschool children with attention-deficit-hyperactivity disorder. Dev Med Child Neurol 48:483–488
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Kieling, R., Rohde, L.A. (2010). ADHD in Children and Adults: Diagnosis and Prognosis. In: Stanford, C., Tannock, R. (eds) Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder and Its Treatment. Current Topics in Behavioral Neurosciences, vol 9. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7854_2010_115
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DOI: https://doi.org/10.1007/7854_2010_115
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