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Uterine Cancer pp 247-257 | Cite as

Management of Uterine Sarcomas

  • Leslie R. BoydEmail author
Part of the Current Clinical Oncology book series (CCO)

Abstract

Uterine sarcomas, including the subtypes leiomyosarcoma, endometrial stromal sarcoma, and adenosarcoma, are a heterogenous group of tumors which vary widely in their biology and prognosis. Surgery is the mainstay of treatment. The roles of chemotherapy, radiation therapy and hormonal therapy are poorly defined, in large part due to the rarity of these tumors. Prior clinical trials grouped uterine sarcomas together, which helped trial accrual but hampered applicability of trial results. Today’s trials are specific to each histology, and are often supplemented by molecular studies to improve interpretation of results. Continued investigations should point the way for future therapies directed towards these tumors.

Keywords

Adenosarcoma Endometrial stromal sarcoma Gemcitabine Docetaxel Hormonal therapy Leiomyosarcoma Undifferentiated endometrial sarcoma Uterine sarcomas 

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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Division of Gynecologic Oncology, Department of Obstetrics and GynecologyNYU School of MedicineNew YorkUSA

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