Skip to main content

Overview: Transporters as Targets for Drug Discovery

  • Chapter
  • First Online:
Transporters as Targets for Drugs

Part of the book series: Topics in Medicinal Chemistry ((TMC,volume 4))

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Linton KJ (2007) Physiology 22:122

    Article  CAS  Google Scholar 

  2. Davidson AL, Maloney PC (2007) Trends Microbiol 15:448

    Article  CAS  Google Scholar 

  3. Juliano RL, Ling V (1976) Biochim Biophys Acta 455:152

    Article  CAS  Google Scholar 

  4. Szákacs G, Váradi A, Özvegy-Laczka C, Sarkadi B (2008) Drug Discov Today 13:379

    Article  Google Scholar 

  5. Yu DK (1999) J Clin Pharmacol 39:1203

    Article  CAS  Google Scholar 

  6. Keppler D, König J, Büchler M (1997) Adv Enzym Regul 37:321

    Article  CAS  Google Scholar 

  7. Childs S, Yeh RL, Georges E, Ling V (1995) Cancer Res 55:2029

    CAS  Google Scholar 

  8. Doyle L, Yang W, Abruzzo L, Krogmann T, Gao Y, Rishi AK, Ross DD (1998) Proc Natl Acad Sci USA 95:15665

    Article  CAS  Google Scholar 

  9. Miyake K, Mickley L, Litman T, Zhan Z, Robey R, Cristensen B, Brangi M, Greenberger L, Dean M, Fojo T, Bates SE (1999) Cancer Res 59:8

    CAS  Google Scholar 

  10. Rizwan AN, Burckhardt G (2007) Pharmaceut Res 24:450

    Article  CAS  Google Scholar 

  11. Choi M-K, Song I-S (2008) Drug Metab Pharmacokin 23:243

    Article  Google Scholar 

  12. Law CJ, Maloney PC, Wang D-N (2008) Annu Rev Microbiol 62:289

    Article  CAS  Google Scholar 

  13. www.Thomson-pharma.com

    Google Scholar 

  14. Haunso A, Buchanan D (2007) J Biomol Screen 12:378

    Article  CAS  Google Scholar 

  15. Mason JN, Farmar H, Tomlinson ID, Schwartz JW, Savchenko V, DeFelice LJ, Rosenthal SJ, Blakely RD (2005) J Neurosci Methods 143:3

    Article  CAS  Google Scholar 

  16. Jørgensen S, Østergaard N, Peters D, Dyhring T (2008) 169:168

    Google Scholar 

  17. Allan L, Leith JL, Papakosta M, Morrow JA, Irving NG, McFerran BW, Clark AG (2006) Comb Chem High Throughput Screen 9:9

    Article  CAS  Google Scholar 

  18. Benjamin ER, Skelton J, Hanway D, Olanrewaju S, Pruthi F, Ilyin VI, Lavery D, Victory SF, Valenzano KJ (2005) J Biomol Screen 10:365

    Article  CAS  Google Scholar 

  19. Jensen AA, Brauner-Osborne H (2004) Biochem Pharmacol 67:2115

    Article  CAS  Google Scholar 

  20. Abramson J, Smirnova I, Kasho V, Verner G, Kaback HR, Iwata S (2003) 301:610

    Google Scholar 

  21. Yin Y, He X, Szewczyk P, Nguyen T, Chang G (2006) Science 312:714

    Article  Google Scholar 

  22. Huang Y, Lemieux MJ, Song J, Auer M, Wang D-N (2003) Science 301:616

    Article  CAS  Google Scholar 

  23. Kadaba NS, Kaiser JT, Johnson E, Lee A, Rees DC (2008) Science 321:250

    Article  CAS  Google Scholar 

  24. Locher KP, Lee AT, Rees DC (2002) Science 296:1091

    Article  CAS  Google Scholar 

  25. Hvorup RN, Goetz BA, Niederer M, Hollenstein K, Perozo E, Locher KP (2007) Science 317:1387

    Article  CAS  Google Scholar 

  26. Pinkett HW, Lee AT, Lum P, Locher KP, Rees DC (2007) Science 315:373

    Article  CAS  Google Scholar 

  27. Hollenstein K, Frei DC, Locher KP (2007) Nature 446:213

    Article  CAS  Google Scholar 

  28. Oldham ML, Khare D, Quiocho FA, Davidson AL, Chen J (2007) Nature 450:515

    Article  CAS  Google Scholar 

  29. Dawson RJP, Locher KP (2006) Nature 443:180

    Article  CAS  Google Scholar 

  30. Ward A, Reyes CL, Yu J, Roth CB, Chang G (2007) Proc Natl Acad Sci USA 104:19005

    Article  CAS  Google Scholar 

  31. Yamashita A, Singh SK, Kuwate T, Jin Y, Gouaux E (2005) Nature 437:215

    Article  CAS  Google Scholar 

  32. Yernool D, Boudker O, Jin Y, Gouaux E (2004) Nature 431:811

    Article  CAS  Google Scholar 

  33. Singh SK, Yamashita A, Gouaux E (2007) Nature 448:952

    Article  CAS  Google Scholar 

  34. Henry LK, Field JR, Adkins EM, Parnas ML, Vaughan RA, Zou M-F, Newman AH, Blakely RD (2006) J Biol Chem 281:2012

    Article  CAS  Google Scholar 

  35. Paczkowski FA, Sharpe IA, Dutertre S, Lewis RJ (2007) J Biol Chem 282:17837

    Article  CAS  Google Scholar 

  36. Zhou Z, Zhen J, Karpowich NK, Goetz RM, Law CJ, Reith MEA, Wang D-N (2007) Science 317:1390

    Article  CAS  Google Scholar 

  37. Butler SG, Meegan MJ (2008) Curr Med Chem 15:1737

    Article  CAS  Google Scholar 

  38. Chen Z, Skolnick P (2007) Expert Opin Investig Drugs 16:1365

    Article  Google Scholar 

  39. Frampton JE, Plosker GL (2007) CNS Drugs 21:581

    Article  CAS  Google Scholar 

  40. Smith T, Nicholson RA (2007) Vasc Health Risk Manag 3:833

    CAS  Google Scholar 

  41. Üçeleyer N, Offenbächer M, Petzke F, Häuser W, Sommer C (2008) Neuropsych Dis Treat 4:525

    Google Scholar 

  42. Agur W, Abrams P (2007) Expert Rev Obstet Gynecol 2:133

    Article  CAS  Google Scholar 

  43. Hartford JA, Kornstein SB, Liebowitz MC, Pigott TD, Russell JE, Detke MEFG, Walker DE, Ball SEF, Dunayevich EE, Dinkel JE, Erickson JE (2007) Int Clin Psychopharmacol 22:167

    Article  Google Scholar 

  44. Ritz MC, Lamb RJ, Goldberg SR, Kuhar MJ (1987) Science 237:1219

    Article  CAS  Google Scholar 

  45. Rocha BA, Fumagalli F, Gainetdinov RR, Jones SR, Ator R, Giros B, Miller GW, Caron MG (1998) Nat Neurosci 1:132

    Article  CAS  Google Scholar 

  46. Sora I, Wichems C, Takahashi N, Li XF, Zeng Z, Revay R, Lesch KP, Murphy DL, Uhl GR (1998) Proc Natl Acad Sci USA 95:7699

    Article  CAS  Google Scholar 

  47. Guastella J, Brecha N, Weigmann C, Lester HA, Davidson N (1992) Proc Natl Acad Sci USA 89:7189

    Article  CAS  Google Scholar 

  48. Liu QR, López-Corcuera B, Mandiyan S, Nelson H, Nelson N (1993) J Biol Chem 268:22802

    CAS  Google Scholar 

  49. Smith KE, Borden LA, Hartig PR, Branchek T, Weinshank RL (1992) Neuron 8:927

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Matilda Bingham .

Editor information

Susan Napier Matilda Bingham

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Bingham, M., Napier, S. (2009). Overview: Transporters as Targets for Drug Discovery. In: Napier, S., Bingham, M. (eds) Transporters as Targets for Drugs. Topics in Medicinal Chemistry, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7355_2009_029

Download citation

Publish with us

Policies and ethics