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Industrial Approaches Toward API Synthesis Under Continuous-Flow Conditions

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Flow Chemistry for the Synthesis of Heterocycles

Part of the book series: Topics in Heterocyclic Chemistry ((TOPICS,volume 56))

Abstract

The use of continuous-flow chemistry has spread to the wider chemical community and found application for the production of active pharmaceutical ingredients (APIs) as a tool for optimization, process development, and production. Herein are summarized some of the advances made by industry in the field of continuous-manufacturing during the last years.

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Author information

Authors and Affiliations

  1. Biocatalysis and Organic Synthesis Group, Chemistry Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

    Rodrigo O. M. A. de Souza

Authors
  1. Rodrigo O. M. A. de Souza
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Corresponding author

Correspondence to Rodrigo O. M. A. de Souza .

Editor information

Editors and Affiliations

  1. Department of Chemistry, University of Leuven (KU Leuven), Leuven, Belgium

    Upendra K. Sharma

  2. Department of Chemistry, University of Leuven (KU Leuven), Leuven, Belgium

    Erik V. Van der Eycken

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de Souza, R.O.M.A. (2018). Industrial Approaches Toward API Synthesis Under Continuous-Flow Conditions. In: Sharma, U., Van der Eycken, E. (eds) Flow Chemistry for the Synthesis of Heterocycles. Topics in Heterocyclic Chemistry, vol 56. Springer, Cham. https://doi.org/10.1007/7081_2018_25

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